Enterovirus and parechovirus infections in children: Differences in clinical presentation, mechanisms for meningitis without pleocytosis and mechanisms involved in the neurological outcome

SCM de Crom, MT van Hinsbergh, IA van Beijsterveld, AM Tutu-van Furth

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Enterovirus (EV) and Parechovirus (HPeV) are a frequent cause of infection in children. This review gives an overview of possible causes for differences in clinical presentation. EV and HPeV can cause a meningitis with or without pleocytosis. Different possible mechanisms for meningitis without pleocytosis are given. Little is known about the prognosis and long-term effects of EV and HPeV meningitis in children. Only some studies with a small number of children with EV or HPeV meningitis are reported. The different possible mechanisms involved in the neurological outcome after EV or HPeV meningitis will be discussed.

Original languageEnglish
Pages (from-to)150-158
Number of pages9
JournalMinerva pediatrica
Volume71
Issue number2
DOIs
Publication statusPublished - 1 Apr 2019

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