ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension

Ekkehard Grünig, Christina Eichstaedt, Joan-Albert Barberà, Nicola Benjamin, Isabel Blanco, Eduardo Bossone, Antonio Cittadini, Gerry Coghlan, Paul Corris, Michele D'Alto, Antonello D'Andrea, Marion Delcroix, Frances de Man, Sean Gaine, Stefano Ghio, Simon Gibbs, Lina Gumbiene, Luke S Howard, Martin Johnson, Elena Jurevičienė & 16 others David G Kiely, Gabor Kovacs, Alison MacKenzie, Alberto M Marra, Noel McCaffrey, Paul McCaughey, Robert Naeije, Horst Olschewski, Joanna Pepke-Zaba, Abílio Reis, Mário Santos, Stéphanie Saxer, Robert M Tulloh, Silvia Ulrich, Anton Vonk Noordegraaf, Andrew J Peacock

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.

Original languageEnglish
JournalThe European respiratory journal
Volume53
Issue number2
DOIs
Publication statusPublished - Feb 2019

Cite this

Grünig, E., Eichstaedt, C., Barberà, J-A., Benjamin, N., Blanco, I., Bossone, E., ... Peacock, A. J. (2019). ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. The European respiratory journal, 53(2). https://doi.org/10.1183/13993003.00332-2018
Grünig, Ekkehard ; Eichstaedt, Christina ; Barberà, Joan-Albert ; Benjamin, Nicola ; Blanco, Isabel ; Bossone, Eduardo ; Cittadini, Antonio ; Coghlan, Gerry ; Corris, Paul ; D'Alto, Michele ; D'Andrea, Antonello ; Delcroix, Marion ; de Man, Frances ; Gaine, Sean ; Ghio, Stefano ; Gibbs, Simon ; Gumbiene, Lina ; Howard, Luke S ; Johnson, Martin ; Jurevičienė, Elena ; Kiely, David G ; Kovacs, Gabor ; MacKenzie, Alison ; Marra, Alberto M ; McCaffrey, Noel ; McCaughey, Paul ; Naeije, Robert ; Olschewski, Horst ; Pepke-Zaba, Joanna ; Reis, Abílio ; Santos, Mário ; Saxer, Stéphanie ; Tulloh, Robert M ; Ulrich, Silvia ; Vonk Noordegraaf, Anton ; Peacock, Andrew J. / ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. In: The European respiratory journal. 2019 ; Vol. 53, No. 2.
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title = "ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension",
abstract = "Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.",
author = "Ekkehard Gr{\"u}nig and Christina Eichstaedt and Joan-Albert Barber{\`a} and Nicola Benjamin and Isabel Blanco and Eduardo Bossone and Antonio Cittadini and Gerry Coghlan and Paul Corris and Michele D'Alto and Antonello D'Andrea and Marion Delcroix and {de Man}, Frances and Sean Gaine and Stefano Ghio and Simon Gibbs and Lina Gumbiene and Howard, {Luke S} and Martin Johnson and Elena Jurevičienė and Kiely, {David G} and Gabor Kovacs and Alison MacKenzie and Marra, {Alberto M} and Noel McCaffrey and Paul McCaughey and Robert Naeije and Horst Olschewski and Joanna Pepke-Zaba and Ab{\'i}lio Reis and M{\'a}rio Santos and St{\'e}phanie Saxer and Tulloh, {Robert M} and Silvia Ulrich and {Vonk Noordegraaf}, Anton and Peacock, {Andrew J}",
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language = "English",
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Grünig, E, Eichstaedt, C, Barberà, J-A, Benjamin, N, Blanco, I, Bossone, E, Cittadini, A, Coghlan, G, Corris, P, D'Alto, M, D'Andrea, A, Delcroix, M, de Man, F, Gaine, S, Ghio, S, Gibbs, S, Gumbiene, L, Howard, LS, Johnson, M, Jurevičienė, E, Kiely, DG, Kovacs, G, MacKenzie, A, Marra, AM, McCaffrey, N, McCaughey, P, Naeije, R, Olschewski, H, Pepke-Zaba, J, Reis, A, Santos, M, Saxer, S, Tulloh, RM, Ulrich, S, Vonk Noordegraaf, A & Peacock, AJ 2019, 'ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension' The European respiratory journal, vol. 53, no. 2. https://doi.org/10.1183/13993003.00332-2018

ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. / Grünig, Ekkehard; Eichstaedt, Christina; Barberà, Joan-Albert; Benjamin, Nicola; Blanco, Isabel; Bossone, Eduardo; Cittadini, Antonio; Coghlan, Gerry; Corris, Paul; D'Alto, Michele; D'Andrea, Antonello; Delcroix, Marion; de Man, Frances; Gaine, Sean; Ghio, Stefano; Gibbs, Simon; Gumbiene, Lina; Howard, Luke S; Johnson, Martin; Jurevičienė, Elena; Kiely, David G; Kovacs, Gabor; MacKenzie, Alison; Marra, Alberto M; McCaffrey, Noel; McCaughey, Paul; Naeije, Robert; Olschewski, Horst; Pepke-Zaba, Joanna; Reis, Abílio; Santos, Mário; Saxer, Stéphanie; Tulloh, Robert M; Ulrich, Silvia; Vonk Noordegraaf, Anton; Peacock, Andrew J.

In: The European respiratory journal, Vol. 53, No. 2, 02.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension

AU - Grünig, Ekkehard

AU - Eichstaedt, Christina

AU - Barberà, Joan-Albert

AU - Benjamin, Nicola

AU - Blanco, Isabel

AU - Bossone, Eduardo

AU - Cittadini, Antonio

AU - Coghlan, Gerry

AU - Corris, Paul

AU - D'Alto, Michele

AU - D'Andrea, Antonello

AU - Delcroix, Marion

AU - de Man, Frances

AU - Gaine, Sean

AU - Ghio, Stefano

AU - Gibbs, Simon

AU - Gumbiene, Lina

AU - Howard, Luke S

AU - Johnson, Martin

AU - Jurevičienė, Elena

AU - Kiely, David G

AU - Kovacs, Gabor

AU - MacKenzie, Alison

AU - Marra, Alberto M

AU - McCaffrey, Noel

AU - McCaughey, Paul

AU - Naeije, Robert

AU - Olschewski, Horst

AU - Pepke-Zaba, Joanna

AU - Reis, Abílio

AU - Santos, Mário

AU - Saxer, Stéphanie

AU - Tulloh, Robert M

AU - Ulrich, Silvia

AU - Vonk Noordegraaf, Anton

AU - Peacock, Andrew J

N1 - Copyright ©ERS 2019.

PY - 2019/2

Y1 - 2019/2

N2 - Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.

AB - Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.

U2 - 10.1183/13993003.00332-2018

DO - 10.1183/13993003.00332-2018

M3 - Article

VL - 53

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 2

ER -