ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

Ursula Nestle, Dirk de Ruysscher, Umberto Ricardi, Xavier Geets, Jose Belderbos, Christoph Pöttgen, Rafal Dziadiuszko, Stephanie Peeters, Yolande Lievens, Coen Hurkmans, Ben Slotman, Sara Ramella, Corinne Faivre-Finn, Fiona McDonald, Farkhad Manapov, Paul Martin Putora, C. cile LePéchoux, Paul van Houtte

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies.
Original languageEnglish
Pages (from-to)1-5
JournalRadiotherapy and Oncology
Volume127
Issue number1
DOIs
Publication statusPublished - 2018

Cite this

Nestle, U., de Ruysscher, D., Ricardi, U., Geets, X., Belderbos, J., Pöttgen, C., ... van Houtte, P. (2018). ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer. Radiotherapy and Oncology, 127(1), 1-5. https://doi.org/10.1016/j.radonc.2018.02.023
Nestle, Ursula ; de Ruysscher, Dirk ; Ricardi, Umberto ; Geets, Xavier ; Belderbos, Jose ; Pöttgen, Christoph ; Dziadiuszko, Rafal ; Peeters, Stephanie ; Lievens, Yolande ; Hurkmans, Coen ; Slotman, Ben ; Ramella, Sara ; Faivre-Finn, Corinne ; McDonald, Fiona ; Manapov, Farkhad ; Putora, Paul Martin ; LePéchoux, C. cile ; van Houtte, Paul. / ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer. In: Radiotherapy and Oncology. 2018 ; Vol. 127, No. 1. pp. 1-5.
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abstract = "Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies.",
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Nestle, U, de Ruysscher, D, Ricardi, U, Geets, X, Belderbos, J, Pöttgen, C, Dziadiuszko, R, Peeters, S, Lievens, Y, Hurkmans, C, Slotman, B, Ramella, S, Faivre-Finn, C, McDonald, F, Manapov, F, Putora, PM, LePéchoux, CC & van Houtte, P 2018, 'ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer' Radiotherapy and Oncology, vol. 127, no. 1, pp. 1-5. https://doi.org/10.1016/j.radonc.2018.02.023

ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer. / Nestle, Ursula; de Ruysscher, Dirk; Ricardi, Umberto; Geets, Xavier; Belderbos, Jose; Pöttgen, Christoph; Dziadiuszko, Rafal; Peeters, Stephanie; Lievens, Yolande; Hurkmans, Coen; Slotman, Ben; Ramella, Sara; Faivre-Finn, Corinne; McDonald, Fiona; Manapov, Farkhad; Putora, Paul Martin; LePéchoux, C. cile; van Houtte, Paul.

In: Radiotherapy and Oncology, Vol. 127, No. 1, 2018, p. 1-5.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer

AU - Nestle, Ursula

AU - de Ruysscher, Dirk

AU - Ricardi, Umberto

AU - Geets, Xavier

AU - Belderbos, Jose

AU - Pöttgen, Christoph

AU - Dziadiuszko, Rafal

AU - Peeters, Stephanie

AU - Lievens, Yolande

AU - Hurkmans, Coen

AU - Slotman, Ben

AU - Ramella, Sara

AU - Faivre-Finn, Corinne

AU - McDonald, Fiona

AU - Manapov, Farkhad

AU - Putora, Paul Martin

AU - LePéchoux, C. cile

AU - van Houtte, Paul

PY - 2018

Y1 - 2018

N2 - Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies.

AB - Radiotherapy (RT) plays a major role in the curative treatment of locally advanced non-small cell lung cancer (NSCLC). Therefore, the ACROP committee was asked by the ESTRO to provide recommendations on target volume delineation for standard clinical scenarios in definitive (chemo)radiotherapy (RT) and adjuvant RT for locally advanced NSCLC. The guidelines given here are a result of the evaluation of a structured questionnaire followed by a consensus discussion, voting and writing procedure within the committee. Hence, we provide advice for methods and time-points of diagnostics and imaging before the start of treatment planning and for the mandatory and optional imaging to be used for planning itself. Concerning target volumes, recommendations are given for GTV delineation of primary tumour and lymph nodes followed by issues related to the delineation of CTVs for definitive and adjuvant radiotherapy. In the context of PTV delineation, recommendations about the management of geometric uncertainties and target motion are given. We further provide our opinions on normal tissue delineation and organisational and responsibility questions in the process of target volume delineation. This guideline intends to contribute to the standardisation and optimisation of the process of RT treatment planning for clinical practice and prospective studies.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/29605476

U2 - 10.1016/j.radonc.2018.02.023

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