Extensive aortic root endocarditis with extension into the intervalvular fibrous body: an updated report of a mitral valve sparing approach

Anton Tomšič, Meindert Palmen, Mylene Loncq de Jong, Jesper Hjortnaes, Antoine G H Driessen, Jerry Braun, Nina Ajmone Marsan, Robert J M Klautz

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OBJECTIVES: Aortic root abscess can spread to include adjacent cardiac structures, including the central or intervalvular fibrous body and mitral valve. After radical debridement, complex surgical correction is needed. We describe the results of our mitral valve sparing approach.

METHODS: Between January 2004 and December 2020, 60 patients underwent operation for infective endocarditis of the aortic root with extension towards the mitral valve at 2 centers in the Netherlands. Early and late clinical and echocardiographic outcomes were studied.

RESULTS: Prosthetic valve endocarditis was present in 42 (70%) patients and emergent or salvage surgery was performed in 8 (13%) patients. After radical debridement of all infected tissue, mitral valve repair was feasible in 48 (80%) patients. Early mortality occurred in 11 (18%) patients while mechanical circulatory support was needed in 8 (13%) patients. At 10 years after surgery, the estimated reintervention free survival rate was 51.9% (95% confidence interval 37.0%-66.8%). Eight patients underwent reintervention; this was more common in patients who underwent aortic valve rather than root replacement and in patients in whom mitral valve repair was performed without ring annuloplasty. For 48 patients who underwent mitral valve repair, the estimated freedom from recurrent mitral regurgitation rate was 64.4% (95% CI 40.1%-88.7%) at 10 years after surgery.

CONCLUSIONS: Surgical intervention for extensive infective endocarditis of the aortic root is related to reasonable perioperative morbidity and mortality. Optimal surgical technique is crucial to lower the risk of late reintervention. Mitral valve repair is feasible in the majority of patients with satisfactory durability.

Original languageEnglish
JournalEuropean Journal of Cardio-thoracic Surgery
Publication statusE-pub ahead of print - 23 Mar 2023

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