We describe a method to extract the haemodynamic response function (HRF) from functional magnetic resonance imaging (fMRI) time series based on Fourier-wavelet regularised deconvolution (ForWaRD), and introduce a simple model for the HRF. The HRF extraction algorithm extends the ForWaRD algorithm by introducing a more efficient computation in the case of very long wavelet filters. We compute shift-invariant discrete wavelet transforms (SIDWT) in the frequency domain, and apply ForWaRD using orthogonal spline wavelets. Extraction and modelling of subject-specific HRFs is demonstrated, as well as the use of these HRFs in a subsequent brain activation analysis. Temporal responses are predicted by using the extracted HRF coefficients. The resulting activation maps show the effectiveness of the proposed method.
|Publication status||Published - 1 Dec 2006|
|Event||14th European Signal Processing Conference, EUSIPCO 2006 - Florence, Italy|
Duration: 4 Sep 2006 → 8 Sep 2006
|Conference||14th European Signal Processing Conference, EUSIPCO 2006|
|Period||04/09/2006 → 08/09/2006|