Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study

Sietske J. Tamminga, Pieter Coenen, Carmen Paalman, Angela G. E. M. de Boer, Neil K. Aaronson, Hester S. A. Oldenburg, Flora E. van Leeuwen, Allard J. van der Beek, Saskia F. A. Duijts, Michael Schaapveld

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Purpose: To identify which factors are associated with adverse work outcome 5–10 years after diagnosis. Methods: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5–10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20% less compared to prediagnosis. Logistic regression analyses were conducted. Results: Of 906 participants, 326 (36%) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95% CI, 1.00–1.07), time since diagnosis (OR, 1.19; 95% CI, 1.03–1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95% CI, 1.94–4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95% CI, 0.08–0.66), higher total work ability (OR, 0.61; 95% CI, 0.54–0.69), feeling supported at work (OR, 0.52; 95% CI, 0.33–0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95% CI, 0.54–0.79), being able to adjust working hours (OR, 0.55; 95% CI, 0.36–0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95% CI, 1.0–3.2). Conclusions: Predominantly, work-related factors are associated with adverse work outcomes 5–10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. Implications for Cancer Survivors: Work-related factors should be considered in future interventions to prevent adverse work outcome 5–10 years after diagnosis.
Original languageEnglish
Pages (from-to)108-116
JournalJournal of Cancer Survivorship
Volume13
Issue number1
DOIs
Publication statusPublished - 15 Feb 2019

Cite this

Tamminga, Sietske J. ; Coenen, Pieter ; Paalman, Carmen ; de Boer, Angela G. E. M. ; Aaronson, Neil K. ; Oldenburg, Hester S. A. ; van Leeuwen, Flora E. ; van der Beek, Allard J. ; Duijts, Saskia F. A. ; Schaapveld, Michael. / Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study. In: Journal of Cancer Survivorship. 2019 ; Vol. 13, No. 1. pp. 108-116.
@article{7a53794b6e304fbf91c008f27b07815e,
title = "Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study",
abstract = "Purpose: To identify which factors are associated with adverse work outcome 5–10 years after diagnosis. Methods: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5–10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20{\%} less compared to prediagnosis. Logistic regression analyses were conducted. Results: Of 906 participants, 326 (36{\%}) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95{\%} CI, 1.00–1.07), time since diagnosis (OR, 1.19; 95{\%} CI, 1.03–1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95{\%} CI, 1.94–4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95{\%} CI, 0.08–0.66), higher total work ability (OR, 0.61; 95{\%} CI, 0.54–0.69), feeling supported at work (OR, 0.52; 95{\%} CI, 0.33–0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95{\%} CI, 0.54–0.79), being able to adjust working hours (OR, 0.55; 95{\%} CI, 0.36–0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95{\%} CI, 1.0–3.2). Conclusions: Predominantly, work-related factors are associated with adverse work outcomes 5–10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. Implications for Cancer Survivors: Work-related factors should be considered in future interventions to prevent adverse work outcome 5–10 years after diagnosis.",
author = "Tamminga, {Sietske J.} and Pieter Coenen and Carmen Paalman and {de Boer}, {Angela G. E. M.} and Aaronson, {Neil K.} and Oldenburg, {Hester S. A.} and {van Leeuwen}, {Flora E.} and {van der Beek}, {Allard J.} and Duijts, {Saskia F. A.} and Michael Schaapveld",
year = "2019",
month = "2",
day = "15",
doi = "10.1007/s11764-018-0731-7",
language = "English",
volume = "13",
pages = "108--116",
journal = "Journal of Cancer Survivorship",
issn = "1932-2259",
publisher = "Springer New York",
number = "1",

}

Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study. / Tamminga, Sietske J.; Coenen, Pieter; Paalman, Carmen; de Boer, Angela G. E. M.; Aaronson, Neil K.; Oldenburg, Hester S. A.; van Leeuwen, Flora E.; van der Beek, Allard J.; Duijts, Saskia F. A.; Schaapveld, Michael.

In: Journal of Cancer Survivorship, Vol. 13, No. 1, 15.02.2019, p. 108-116.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study

AU - Tamminga, Sietske J.

AU - Coenen, Pieter

AU - Paalman, Carmen

AU - de Boer, Angela G. E. M.

AU - Aaronson, Neil K.

AU - Oldenburg, Hester S. A.

AU - van Leeuwen, Flora E.

AU - van der Beek, Allard J.

AU - Duijts, Saskia F. A.

AU - Schaapveld, Michael

PY - 2019/2/15

Y1 - 2019/2/15

N2 - Purpose: To identify which factors are associated with adverse work outcome 5–10 years after diagnosis. Methods: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5–10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20% less compared to prediagnosis. Logistic regression analyses were conducted. Results: Of 906 participants, 326 (36%) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95% CI, 1.00–1.07), time since diagnosis (OR, 1.19; 95% CI, 1.03–1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95% CI, 1.94–4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95% CI, 0.08–0.66), higher total work ability (OR, 0.61; 95% CI, 0.54–0.69), feeling supported at work (OR, 0.52; 95% CI, 0.33–0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95% CI, 0.54–0.79), being able to adjust working hours (OR, 0.55; 95% CI, 0.36–0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95% CI, 1.0–3.2). Conclusions: Predominantly, work-related factors are associated with adverse work outcomes 5–10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. Implications for Cancer Survivors: Work-related factors should be considered in future interventions to prevent adverse work outcome 5–10 years after diagnosis.

AB - Purpose: To identify which factors are associated with adverse work outcome 5–10 years after diagnosis. Methods: In this cross-sectional study, breast cancer survivors, treated between 2003 and 2008, completed a questionnaire 5–10 years after diagnosis. Adverse work outcome was defined as not having paid employment or working > 20% less compared to prediagnosis. Logistic regression analyses were conducted. Results: Of 906 participants, 326 (36%) had an adverse work outcome. In multivariable analyses, the probability of an adverse work outcome increased with age (OR, 1.03; 95% CI, 1.00–1.07), time since diagnosis (OR, 1.19; 95% CI, 1.03–1.37), and was higher among women who stated that work had become less important (OR, 2.99; 95% CI, 1.94–4.62). Factors associated with a lower probability of an adverse work outcome were having sufficient financial resources (OR, 0.23; 95% CI, 0.08–0.66), higher total work ability (OR, 0.61; 95% CI, 0.54–0.69), feeling supported at work (OR, 0.52; 95% CI, 0.33–0.80), and, prior to diagnosis, having more children to take care of (OR, 0.65; 95% CI, 0.54–0.79), being able to adjust working hours (OR, 0.55; 95% CI, 0.36–0.83) and not desiring to work less hours if that were to be financially feasible (OR, 1.8; 95% CI, 1.0–3.2). Conclusions: Predominantly, work-related factors are associated with adverse work outcomes 5–10 years after diagnosis, whereas clinical factors are not. Our results need validation in prospective cohort studies, after which supportive interventions could be developed. Implications for Cancer Survivors: Work-related factors should be considered in future interventions to prevent adverse work outcome 5–10 years after diagnosis.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060100066&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/30637577

U2 - 10.1007/s11764-018-0731-7

DO - 10.1007/s11764-018-0731-7

M3 - Article

VL - 13

SP - 108

EP - 116

JO - Journal of Cancer Survivorship

JF - Journal of Cancer Survivorship

SN - 1932-2259

IS - 1

ER -