Familial cortical tremor with epilepsy and cerebellar pathological findings

Anne Fleur van Rootselaar, Eleonora Aronica, Ernst N.H. Jansen Steur, Johanna M. Rozemuller-Kwakkel, Rob A.I. de Vos, Marina A.J. Tijssen

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The clinical and neuropathological findings in a patient with familial cortical tremor with epilepsy (FCTE) are described. Clinically, the patient showed cortical myoclonus, tremor, and generalized seizures. Pathological investigation showed cerebellar degeneration and somal sprouting and loss of dendritic tree in Purkinje cells. Striking similarities were found in diseases caused by channelopathies such as spinocerebellar ataxia subtype 6.

Original languageEnglish
Pages (from-to)213-217
Number of pages5
JournalMovement Disorders
Issue number2
Publication statusPublished - 19 Mar 2004

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