Fatty Acid Oxidation in Macrophages and T Cells: Time for Reassessment?

Jan Van den Bossche, Gerritje J W van der Windt

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Previous immunometabolism research using the CPT1 inhibitor etomoxir suggests that long-chain fatty acid oxidation (LC-FAO) supports IL-4-driven alternative macrophage activation (M(IL-4)) and regulates memory and regulatory T cell formation. Divakaruni et al. (2018) and Raud et al. (2018) now report that LC-FAO is largely dispensable for these processes.

Original languageEnglish
Pages (from-to)538-540
Number of pages3
JournalCell Metabolism
Volume28
Issue number4
DOIs
Publication statusPublished - 2 Oct 2018

Cite this

Van den Bossche, Jan ; van der Windt, Gerritje J W. / Fatty Acid Oxidation in Macrophages and T Cells : Time for Reassessment?. In: Cell Metabolism. 2018 ; Vol. 28, No. 4. pp. 538-540.
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abstract = "Previous immunometabolism research using the CPT1 inhibitor etomoxir suggests that long-chain fatty acid oxidation (LC-FAO) supports IL-4-driven alternative macrophage activation (M(IL-4)) and regulates memory and regulatory T cell formation. Divakaruni et al. (2018) and Raud et al. (2018) now report that LC-FAO is largely dispensable for these processes.",
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Fatty Acid Oxidation in Macrophages and T Cells : Time for Reassessment? / Van den Bossche, Jan; van der Windt, Gerritje J W.

In: Cell Metabolism, Vol. 28, No. 4, 02.10.2018, p. 538-540.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Fatty Acid Oxidation in Macrophages and T Cells

T2 - Time for Reassessment?

AU - Van den Bossche, Jan

AU - van der Windt, Gerritje J W

N1 - Copyright © 2018 Elsevier Inc. All rights reserved.

PY - 2018/10/2

Y1 - 2018/10/2

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AB - Previous immunometabolism research using the CPT1 inhibitor etomoxir suggests that long-chain fatty acid oxidation (LC-FAO) supports IL-4-driven alternative macrophage activation (M(IL-4)) and regulates memory and regulatory T cell formation. Divakaruni et al. (2018) and Raud et al. (2018) now report that LC-FAO is largely dispensable for these processes.

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SN - 1550-4131

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