Abstract

BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.
Original languageDutch
JournalNederlands Tijdschrift voor Geneeskunde
Volume163
Publication statusPublished - 2019

Cite this

@article{f30c6417e69f4094a30fb5cd75ebeaa6,
title = "Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties",
abstract = "BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.",
author = "Ooijevaar, {Rogier E.} and {van Rossen}, {Tessel M.} and Vandenbroucke-Grauls, {Christina M. J. E.} and Budding, {Andries E.} and Kneepkens, {C. M. F.} and {de Meij}, {Tim G. J.}",
year = "2019",
language = "Dutch",
volume = "163",
journal = "Nederlands Tijdschrift voor Geneeskunde",
issn = "0028-2162",
publisher = "Bohn Stafleu van Loghum",

}

TY - JOUR

T1 - Fecestransplantatie voor kinderen met recidiverende C. difficile-infecties

AU - Ooijevaar, Rogier E.

AU - van Rossen, Tessel M.

AU - Vandenbroucke-Grauls, Christina M. J. E.

AU - Budding, Andries E.

AU - Kneepkens, C. M. F.

AU - de Meij, Tim G. J.

PY - 2019

Y1 - 2019

N2 - BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.

AB - BACKGROUND: Clostridioides difficile infection is a relatively rare cause of diarrhoea in children, but there are frequent recurrences when it occurs, despite targeted antibiotic treatment. CASE DESCRIPTIONS: A 2-year-old boy with concomitant motility disorder and a 14-year-old girl with Down syndrome experienced several infections with C. difficile, respectively after the use of antibiotics for otitis media and extended use of antibiotics in addition to chemotherapy. Both were treated successfully with faecal transplants. CONCLUSION: Clostridioides difficile infections occur in children, mainly after extended use of antibiotics or when the immune system is impaired. In case of recurring C. difficile infections, children can be treated safely and effectively with faecal transplants.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85070822189&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/31361420

M3 - Article

VL - 163

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

SN - 0028-2162

ER -