SYNOPSISGranisetron (BRL 43694), a selective 5‐HT3 receptor antagonist, was assessed as acute therapy for the first time in migraine patients. In an open pilot study 7 migraine attacks were treated in 6 patients. All but I patient experienced marked and rapid relief from the headache, and nausea and vomiting were rapidly resolved in the 6 cases where these symptoms accompanied the attack. No side effects were recorded. Development of granisetron for migraine was suspended during the study for extraneous reasons.
|Number of pages||2|
|Journal||Headache: The Journal of Head and Face Pain|
|Publication status||Published - 1 Jan 1991|