Fluorine-18 fluorodeoxyglucose positron emission tomography (PET) to detect vital retinoblastoma in the eye: Preliminary experience

A. C. Moll*, O. S. Hoekstra, S. M. Imhof, E. F. Comans, A. Y.N. Schouten-Van Meeteren, P. Van Der Valk, M. Boers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background/aims: To report our first experience with FDG-PET in the detection of vital retinoblastoma. Methods: Four newly diagnosed retinoblastoma patients, two treated retinoblastoma patients, and four control patients were enrolled in this pilot study. F18-FDG uptake was assessed in the light of clinical and histopathological features. Results: PET discriminated between new patients and controls, although tumor uptake varied widely. PET added no useful information with regard to possible vital tissue in tumor scars in the eye of the two treated retinoblastoma patients. Moreover, PET findings did not correlate with clinical or histopathological features. Conclusion: Based on this small pilot study, F18-PET shows little promise in the detection of retinoblastoma. More research on other radiofarmacons is recommended.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalOphthalmic Genetics
Volume25
Issue number1
DOIs
Publication statusPublished - Mar 2004

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