Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz, Shachar Raz, Michal Stark, Yehuda G. Assaraf, Gerrit Jansen, Godefridus J. Peters, Edwin Sonneveld, Gertjan J. L. Kaspers, Jacqueline Cloos

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1645-1656
JournalInternational Journal of Cancer
Volume138
Issue number7
DOIs
Publication statusPublished - 1 Apr 2016

Cite this

@article{5fb043445445407c8ffb478bcb89469a,
title = "Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance",
keywords = "folylpolyglutamate synthetase, methotrexate, alternative splicing, drug resistance, acute lymphoblastic leukemia",
author = "Anna Wojtuszkiewicz and Shachar Raz and Michal Stark and Assaraf, {Yehuda G.} and Gerrit Jansen and Peters, {Godefridus J.} and Edwin Sonneveld and Kaspers, {Gertjan J. L.} and Jacqueline Cloos",
year = "2016",
month = "4",
day = "1",
doi = "10.1002/ijc.29919",
language = "English",
volume = "138",
pages = "1645--1656",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "Wiley-Liss Inc.",
number = "7",

}

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. / Wojtuszkiewicz, Anna; Raz, Shachar; Stark, Michal; Assaraf, Yehuda G.; Jansen, Gerrit; Peters, Godefridus J.; Sonneveld, Edwin; Kaspers, Gertjan J. L.; Cloos, Jacqueline.

In: International Journal of Cancer, Vol. 138, No. 7, 01.04.2016, p. 1645-1656.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

AU - Wojtuszkiewicz, Anna

AU - Raz, Shachar

AU - Stark, Michal

AU - Assaraf, Yehuda G.

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Sonneveld, Edwin

AU - Kaspers, Gertjan J. L.

AU - Cloos, Jacqueline

PY - 2016/4/1

Y1 - 2016/4/1

KW - folylpolyglutamate synthetase

KW - methotrexate

KW - alternative splicing

KW - drug resistance

KW - acute lymphoblastic leukemia

U2 - 10.1002/ijc.29919

DO - 10.1002/ijc.29919

M3 - Article

VL - 138

SP - 1645

EP - 1656

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 7

ER -