Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz; Shachar Raz; Michal Stark; Yehuda G. Assaraf; Gerrit Jansen; Godefridus J. Peters; Edwin Sonneveld; Gertjan J. L. Kaspers; Jacqueline Cloos

doi:10.1002/ijc.29919

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz, Shachar Raz, Michal Stark, Yehuda G. Assaraf, Gerrit Jansen, Godefridus J. Peters, Edwin Sonneveld, Gertjan J. L. Kaspers, Jacqueline Cloos

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1645-1656
Journal	International Journal of Cancer
Volume	138
Issue number	7
DOIs	https://doi.org/10.1002/ijc.29919
Publication status	Published - 1 Apr 2016

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10.1002/ijc.29919

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Wojtuszkiewicz, A., Raz, S., Stark, M., Assaraf, Y. G., Jansen, G., Peters, G. J., Sonneveld, E., Kaspers, G. J. L., & Cloos, J. (2016). Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. International Journal of Cancer, 138(7), 1645-1656. https://doi.org/10.1002/ijc.29919

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title = "Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance",

keywords = "folylpolyglutamate synthetase, methotrexate, alternative splicing, drug resistance, acute lymphoblastic leukemia",

author = "Anna Wojtuszkiewicz and Shachar Raz and Michal Stark and Assaraf, {Yehuda G.} and Gerrit Jansen and Peters, {Godefridus J.} and Edwin Sonneveld and Kaspers, {Gertjan J. L.} and Jacqueline Cloos",

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Wojtuszkiewicz, A, Raz, S, Stark, M, Assaraf, YG, Jansen, G , Peters, GJ, Sonneveld, E, Kaspers, GJL & Cloos, J 2016, 'Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance', International Journal of Cancer, vol. 138, no. 7, pp. 1645-1656. https://doi.org/10.1002/ijc.29919

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance. / Wojtuszkiewicz, Anna; Raz, Shachar; Stark, Michal et al.
In: International Journal of Cancer, Vol. 138, No. 7, 01.04.2016, p. 1645-1656.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

AU - Wojtuszkiewicz, Anna

AU - Raz, Shachar

AU - Stark, Michal

AU - Assaraf, Yehuda G.

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Sonneveld, Edwin

AU - Kaspers, Gertjan J. L.

AU - Cloos, Jacqueline

PY - 2016/4/1

Y1 - 2016/4/1

KW - folylpolyglutamate synthetase

KW - methotrexate

KW - alternative splicing

KW - drug resistance

KW - acute lymphoblastic leukemia

U2 - 10.1002/ijc.29919

DO - 10.1002/ijc.29919

M3 - Article

C2 - 26547381

SN - 0020-7136

VL - 138

SP - 1645

EP - 1656

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 7

ER -