From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer

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Western and Eastern practices have traditionally differed in their approach to treating lateral lymph nodes in rectal cancer. While Western clinicians have primarily favored neoadjuvant (chemo)radiotherapy to sterilize lateral compartments, Eastern physicians have often opted for the surgical removed of lymphatic tissue with a lateral lymph node dissection without neoadjuvant treatment. The literature suggests similar oncological outcomes for these two separate techniques, while tangible differences exist. The combination of these paradigms may be beneficial in reducing overall morbidity while sustaining low recurrence rates. This article considers traditional Eastern and Western perspectives, discusses nodal features important for predicting malignancy and attempts to stimulate international, multidisciplinary consensus and collaboration.
Original languageEnglish
Pages (from-to)731-737
Number of pages7
JournalAnnals of Gastroenterological Surgery
Issue number6
Early online date9 Aug 2021
Publication statusPublished - Nov 2021

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