FTO genotype is associated with phenotypic variability of body mass index

J. Yang; R.J. Loos; J.E. Powell; S.E. Medland; E.K. Speliotes; D.I. Chasman; L.M. Rose; G. Thorleifsson; V. Steinthorsdottir; R. Mägi; L. Waite; A.V. Smith; L.M. Yerges-Armstrong; K.L. Monda; D. Hadley; A. Mahajan; G. Li; K. Kapur; V. Vitart; J.E. Huffman; S.R. Wang; C. Palmer; T. Esko; K. Fischer; J.H. Zhao; A. Demirkan; A. Isaacs; M.F. Feitosa; J. Luan; N.L. Heard-Costa; C. White; A.U. Jackson; M Preuss; A. Ziegler; J. Eriksson; Z. Kutalik; F. Frau; I.M. Nolte; J.V. van Vliet-Ostaptchouk; J.J. Hottenga; K.B. Jacobs; N. Verweij; A. Goel; C. Medina-Gomez; K. Estrada; J.L. Bragg-Gresham; S. Sanna; C. Sidore; J. Tyrer; A. Teumer; I. Prokopenko; M. Mangino; C.M. Lindgren; T.L. Assimes; A.R. Shuldiner; J. Hui; J.P. Beilby; W.L. McArdle; P. Hall; T. Haritunians; L. Zgaga; I. Kolcic; O. Polasek; T. Zemunik; B.A. Oostra; M.J. Junttila; H. Grönberg; S Schreiber; A. Peters; A.A. Hicks; J. Stephens; N.S. Foad; J. Laitinen; A. Pouta; M. Kaakinen; G. Willemsen; J.M. Vink; S.H. Wild; G. Navis; F.W. Asselbergs; G. Homuth; U. John; C. Iribarren; T. Harris; L.J. Launer; V. Gudnason; J.R. O'Connell; E. Boerwinkle; G. Cadby; L.J. Palmer; A.L. James; A.W. Musk; E. Ingelsson; B.M. Psaty; J.S. Beckmann; G. Waeber; P. Vollenweider; C. Hayward; A.F. Wright; I. Rudan; L.C. Groop; A. Metspalu; K. Thee Khaw; C.M. van Duijn; I.B. Borecki; M.A. Province; N.J. Wareham; J.C. Tardif; H.V. Huikuri; L.A. Cupples; L.D. Atwood; C.S. Fox; M. Boehnke; F.S. Collins; K.L. Mohlke; J. Erdmann; H. Schunkert; C. Hengstenberg; K. Stark; M. Lorentzon; C. Ohlsson; D. Cusi; J.A. Staessen; M.M. van der Klauw; P.P. Pramstaller; S. Kathiresan; D.J. Jolley; S. Ripatti; M.-R. Jarvelin; E.J.C. de Geus; D.I. Boomsma; B.W.J.H. Penninx; J.F. Wilson; H. Campbell; S.J. Chanock; P. van der Harst; A. Hamsten; H. Watkins; A. Hofman; J.C. Witteman; M.C. Zillikens; A.G. Uitterlinden; F. Rivadeneira; L.A. Kiemeney; S.H. Vermeulen; G.R. Abecasis; D. Schlessinger; S. Schipf; M. Stumvoll; A. Tönjes; T.D. Spector; K.E. North; G. Lettre; M.I. McCarthy; S.I. Berndt; A.C. Heath; P.A.F. Madden; DR Nyholt; G.W. Montgomery; N.G. Martin; B. McKnight; D.P. Strachan; W.G. Hill; H. Snieder; P.M. Ridker; U. Thorsteinsdottir; K. Stefansson; T.M. Frayling; J.N. Hirschhorn; M.E. Goddard; P.M. Visscher

doi:10.1038/nature11401

FTO genotype is associated with phenotypic variability of body mass index

J. Yang, R.J. Loos, J.E. Powell, S.E. Medland, E.K. Speliotes, D.I. Chasman, L.M. Rose, G. Thorleifsson, V. Steinthorsdottir, R. Mägi, L. Waite, A.V. Smith, L.M. Yerges-Armstrong, K.L. Monda, D. Hadley, A. Mahajan, G. Li, K. Kapur, V. Vitart, J.E. HuffmanS.R. Wang, C. Palmer, T. Esko, K. Fischer, J.H. Zhao, A. Demirkan, A. Isaacs, M.F. Feitosa, J. Luan, N.L. Heard-Costa, C. White, A.U. Jackson, M Preuss, A. Ziegler, J. Eriksson, Z. Kutalik, F. Frau, I.M. Nolte, J.V. van Vliet-Ostaptchouk, J.J. Hottenga, K.B. Jacobs, N. Verweij, A. Goel, C. Medina-Gomez, K. Estrada, J.L. Bragg-Gresham, S. Sanna, C. Sidore, J. Tyrer, A. Teumer, I. Prokopenko, M. Mangino, C.M. Lindgren, T.L. Assimes, A.R. Shuldiner, J. Hui, J.P. Beilby, W.L. McArdle, P. Hall, T. Haritunians, L. Zgaga, I. Kolcic, O. Polasek, T. Zemunik, B.A. Oostra, M.J. Junttila, H. Grönberg, S Schreiber, A. Peters, A.A. Hicks, J. Stephens, N.S. Foad, J. Laitinen, A. Pouta, M. Kaakinen, G. Willemsen, J.M. Vink, S.H. Wild, G. Navis, F.W. Asselbergs, G. Homuth, U. John, C. Iribarren, T. Harris, L.J. Launer, V. Gudnason, J.R. O'Connell, E. Boerwinkle, G. Cadby, L.J. Palmer, A.L. James, A.W. Musk, E. Ingelsson, B.M. Psaty, J.S. Beckmann, G. Waeber, P. Vollenweider, C. Hayward, A.F. Wright, I. Rudan, L.C. Groop, A. Metspalu, K. Thee Khaw, C.M. van Duijn, I.B. Borecki, M.A. Province, N.J. Wareham, J.C. Tardif, H.V. Huikuri, L.A. Cupples, L.D. Atwood, C.S. Fox, M. Boehnke, F.S. Collins, K.L. Mohlke, J. Erdmann, H. Schunkert, C. Hengstenberg, K. Stark, M. Lorentzon, C. Ohlsson, D. Cusi, J.A. Staessen, M.M. van der Klauw, P.P. Pramstaller, S. Kathiresan, D.J. Jolley, S. Ripatti, M.-R. Jarvelin, E.J.C. de Geus, D.I. Boomsma, B.W.J.H. Penninx, J.F. Wilson, H. Campbell, S.J. Chanock, P. van der Harst, A. Hamsten, H. Watkins, A. Hofman, J.C. Witteman, M.C. Zillikens, A.G. Uitterlinden, F. Rivadeneira, L.A. Kiemeney, S.H. Vermeulen, G.R. Abecasis, D. Schlessinger, S. Schipf, M. Stumvoll, A. Tönjes, T.D. Spector, K.E. North, G. Lettre, M.I. McCarthy, S.I. Berndt, A.C. Heath, P.A.F. Madden, DR Nyholt, G.W. Montgomery, N.G. Martin, B. McKnight, D.P. Strachan, W.G. Hill, H. Snieder, P.M. Ridker, U. Thorsteinsdottir, K. Stefansson, T.M. Frayling, J.N. Hirschhorn, M.E. Goddard, P.M. Visscher

Psychiatry

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	267-272
Journal	Nature
Volume	490
Issue number	7419
DOIs	https://doi.org/10.1038/nature11401
Publication status	Published - 2012

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10.1038/nature11401

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Yang, J., Loos, R. J., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., ... Visscher, P. M. (2012). FTO genotype is associated with phenotypic variability of body mass index. Nature, 490(7419), 267-272. https://doi.org/10.1038/nature11401

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title = "FTO genotype is associated with phenotypic variability of body mass index",

author = "J. Yang and R.J. Loos and J.E. Powell and S.E. Medland and E.K. Speliotes and D.I. Chasman and L.M. Rose and G. Thorleifsson and V. Steinthorsdottir and R. M{\"a}gi and L. Waite and A.V. Smith and L.M. Yerges-Armstrong and K.L. Monda and D. Hadley and A. Mahajan and G. Li and K. Kapur and V. Vitart and J.E. Huffman and S.R. Wang and C. Palmer and T. Esko and K. Fischer and J.H. Zhao and A. Demirkan and A. Isaacs and M.F. Feitosa and J. Luan and N.L. Heard-Costa and C. White and A.U. Jackson and M Preuss and A. Ziegler and J. Eriksson and Z. Kutalik and F. Frau and I.M. Nolte and {van Vliet-Ostaptchouk}, J.V. and J.J. Hottenga and K.B. Jacobs and N. Verweij and A. Goel and C. Medina-Gomez and K. Estrada and J.L. Bragg-Gresham and S. Sanna and C. Sidore and J. Tyrer and A. Teumer and I. Prokopenko and M. Mangino and C.M. Lindgren and T.L. Assimes and A.R. Shuldiner and J. Hui and J.P. Beilby and W.L. McArdle and P. Hall and T. Haritunians and L. Zgaga and I. Kolcic and O. Polasek and T. Zemunik and B.A. Oostra and M.J. Junttila and H. Gr{\"o}nberg and S Schreiber and A. Peters and A.A. Hicks and J. Stephens and N.S. Foad and J. Laitinen and A. Pouta and M. Kaakinen and G. Willemsen and J.M. Vink and S.H. Wild and G. Navis and F.W. Asselbergs and G. Homuth and U. John and C. Iribarren and T. Harris and L.J. Launer and V. Gudnason and J.R. O'Connell and E. Boerwinkle and G. Cadby and L.J. Palmer and A.L. James and A.W. Musk and E. Ingelsson and B.M. Psaty and J.S. Beckmann and G. Waeber and P. Vollenweider and C. Hayward and A.F. Wright and I. Rudan and L.C. Groop and A. Metspalu and {Thee Khaw}, K. and {van Duijn}, C.M. and I.B. Borecki and M.A. Province and N.J. Wareham and J.C. Tardif and H.V. Huikuri and L.A. Cupples and L.D. Atwood and C.S. Fox and M. Boehnke and F.S. Collins and K.L. Mohlke and J. Erdmann and H. Schunkert and C. Hengstenberg and K. Stark and M. Lorentzon and C. Ohlsson and D. Cusi and J.A. Staessen and {van der Klauw}, M.M. and P.P. Pramstaller and S. Kathiresan and D.J. Jolley and S. Ripatti and M.-R. Jarvelin and {de Geus}, E.J.C. and D.I. Boomsma and B.W.J.H. Penninx and J.F. Wilson and H. Campbell and S.J. Chanock and {van der Harst}, P. and A. Hamsten and H. Watkins and A. Hofman and J.C. Witteman and M.C. Zillikens and A.G. Uitterlinden and F. Rivadeneira and L.A. Kiemeney and S.H. Vermeulen and G.R. Abecasis and D. Schlessinger and S. Schipf and M. Stumvoll and A. T{\"o}njes and T.D. Spector and K.E. North and G. Lettre and M.I. McCarthy and S.I. Berndt and A.C. Heath and P.A.F. Madden and DR Nyholt and G.W. Montgomery and N.G. Martin and B. McKnight and D.P. Strachan and W.G. Hill and H. Snieder and P.M. Ridker and U. Thorsteinsdottir and K. Stefansson and T.M. Frayling and J.N. Hirschhorn and M.E. Goddard and P.M. Visscher",

year = "2012",

doi = "10.1038/nature11401",

language = "English",

volume = "490",

pages = "267--272",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "7419",

}

Yang, J, Loos, RJ, Powell, JE, Medland, SE, Speliotes, EK, Chasman, DI, Rose, LM, Thorleifsson, G, Steinthorsdottir, V, Mägi, R, Waite, L, Smith, AV, Yerges-Armstrong, LM, Monda, KL, Hadley, D, Mahajan, A, Li, G, Kapur, K, Vitart, V, Huffman, JE, Wang, SR, Palmer, C, Esko, T, Fischer, K, Zhao, JH, Demirkan, A, Isaacs, A, Feitosa, MF, Luan, J, Heard-Costa, NL, White, C, Jackson, AU, Preuss, M, Ziegler, A, Eriksson, J, Kutalik, Z, Frau, F, Nolte, IM, van Vliet-Ostaptchouk, JV, Hottenga, JJ, Jacobs, KB, Verweij, N, Goel, A, Medina-Gomez, C, Estrada, K, Bragg-Gresham, JL, Sanna, S, Sidore, C, Tyrer, J, Teumer, A, Prokopenko, I, Mangino, M, Lindgren, CM, Assimes, TL, Shuldiner, AR, Hui, J, Beilby, JP, McArdle, WL, Hall, P, Haritunians, T, Zgaga, L, Kolcic, I, Polasek, O, Zemunik, T, Oostra, BA, Junttila, MJ, Grönberg, H, Schreiber, S, Peters, A, Hicks, AA, Stephens, J, Foad, NS, Laitinen, J, Pouta, A, Kaakinen, M, Willemsen, G, Vink, JM, Wild, SH, Navis, G, Asselbergs, FW, Homuth, G, John, U, Iribarren, C, Harris, T, Launer, LJ, Gudnason, V, O'Connell, JR, Boerwinkle, E, Cadby, G, Palmer, LJ, James, AL, Musk, AW, Ingelsson, E, Psaty, BM, Beckmann, JS, Waeber, G, Vollenweider, P, Hayward, C, Wright, AF, Rudan, I, Groop, LC, Metspalu, A, Thee Khaw, K, van Duijn, CM, Borecki, IB, Province, MA, Wareham, NJ, Tardif, JC, Huikuri, HV, Cupples, LA, Atwood, LD, Fox, CS, Boehnke, M, Collins, FS, Mohlke, KL, Erdmann, J, Schunkert, H, Hengstenberg, C, Stark, K, Lorentzon, M, Ohlsson, C, Cusi, D, Staessen, JA, van der Klauw, MM, Pramstaller, PP, Kathiresan, S, Jolley, DJ, Ripatti, S, Jarvelin, M-R, de Geus, EJC, Boomsma, DI, Penninx, BWJH, Wilson, JF, Campbell, H, Chanock, SJ, van der Harst, P, Hamsten, A, Watkins, H, Hofman, A, Witteman, JC, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Kiemeney, LA, Vermeulen, SH, Abecasis, GR, Schlessinger, D, Schipf, S, Stumvoll, M, Tönjes, A, Spector, TD, North, KE, Lettre, G, McCarthy, MI, Berndt, SI, Heath, AC, Madden, PAF, Nyholt, DR, Montgomery, GW, Martin, NG, McKnight, B, Strachan, DP, Hill, WG, Snieder, H, Ridker, PM, Thorsteinsdottir, U, Stefansson, K, Frayling, TM, Hirschhorn, JN, Goddard, ME & Visscher, PM 2012, 'FTO genotype is associated with phenotypic variability of body mass index', Nature, vol. 490, no. 7419, pp. 267-272. https://doi.org/10.1038/nature11401

TY - JOUR

T1 - FTO genotype is associated with phenotypic variability of body mass index

AU - Yang, J.

AU - Loos, R.J.

AU - Powell, J.E.

AU - Medland, S.E.

AU - Speliotes, E.K.

AU - Chasman, D.I.

AU - Rose, L.M.

AU - Thorleifsson, G.

AU - Steinthorsdottir, V.

AU - Mägi, R.

AU - Waite, L.

AU - Smith, A.V.

AU - Yerges-Armstrong, L.M.

AU - Monda, K.L.

AU - Hadley, D.

AU - Mahajan, A.

AU - Li, G.

AU - Kapur, K.

AU - Vitart, V.

AU - Huffman, J.E.

AU - Wang, S.R.

AU - Palmer, C.

AU - Esko, T.

AU - Fischer, K.

AU - Zhao, J.H.

AU - Demirkan, A.

AU - Isaacs, A.

AU - Feitosa, M.F.

AU - Luan, J.

AU - Heard-Costa, N.L.

AU - White, C.

AU - Jackson, A.U.

AU - Preuss, M

AU - Ziegler, A.

AU - Eriksson, J.

AU - Kutalik, Z.

AU - Frau, F.

AU - Nolte, I.M.

AU - van Vliet-Ostaptchouk, J.V.

AU - Hottenga, J.J.

AU - Jacobs, K.B.

AU - Verweij, N.

AU - Goel, A.

AU - Medina-Gomez, C.

AU - Estrada, K.

AU - Bragg-Gresham, J.L.

AU - Sanna, S.

AU - Sidore, C.

AU - Tyrer, J.

AU - Teumer, A.

AU - Prokopenko, I.

AU - Mangino, M.

AU - Lindgren, C.M.

AU - Assimes, T.L.

AU - Shuldiner, A.R.

AU - Hui, J.

AU - Beilby, J.P.

AU - McArdle, W.L.

AU - Hall, P.

AU - Haritunians, T.

AU - Zgaga, L.

AU - Kolcic, I.

AU - Polasek, O.

AU - Zemunik, T.

AU - Oostra, B.A.

AU - Junttila, M.J.

AU - Grönberg, H.

AU - Schreiber, S

AU - Peters, A.

AU - Hicks, A.A.

AU - Stephens, J.

AU - Foad, N.S.

AU - Laitinen, J.

AU - Pouta, A.

AU - Kaakinen, M.

AU - Willemsen, G.

AU - Vink, J.M.

AU - Wild, S.H.

AU - Navis, G.

AU - Asselbergs, F.W.

AU - Homuth, G.

AU - John, U.

AU - Iribarren, C.

AU - Harris, T.

AU - Launer, L.J.

AU - Gudnason, V.

AU - O'Connell, J.R.

AU - Boerwinkle, E.

AU - Cadby, G.

AU - Palmer, L.J.

AU - James, A.L.

AU - Musk, A.W.

AU - Ingelsson, E.

AU - Psaty, B.M.

AU - Beckmann, J.S.

AU - Waeber, G.

AU - Vollenweider, P.

AU - Hayward, C.

AU - Wright, A.F.

AU - Rudan, I.

AU - Groop, L.C.

AU - Metspalu, A.

AU - Thee Khaw, K.

AU - van Duijn, C.M.

AU - Borecki, I.B.

AU - Province, M.A.

AU - Wareham, N.J.

AU - Tardif, J.C.

AU - Huikuri, H.V.

AU - Cupples, L.A.

AU - Atwood, L.D.

AU - Fox, C.S.

AU - Boehnke, M.

AU - Collins, F.S.

AU - Mohlke, K.L.

AU - Erdmann, J.

AU - Schunkert, H.

AU - Hengstenberg, C.

AU - Stark, K.

AU - Lorentzon, M.

AU - Ohlsson, C.

AU - Cusi, D.

AU - Staessen, J.A.

AU - van der Klauw, M.M.

AU - Pramstaller, P.P.

AU - Kathiresan, S.

AU - Jolley, D.J.

AU - Ripatti, S.

AU - Jarvelin, M.-R.

AU - de Geus, E.J.C.

AU - Boomsma, D.I.

AU - Penninx, B.W.J.H.

AU - Wilson, J.F.

AU - Campbell, H.

AU - Chanock, S.J.

AU - van der Harst, P.

AU - Hamsten, A.

AU - Watkins, H.

AU - Hofman, A.

AU - Witteman, J.C.

AU - Zillikens, M.C.

AU - Uitterlinden, A.G.

AU - Rivadeneira, F.

AU - Kiemeney, L.A.

AU - Vermeulen, S.H.

AU - Abecasis, G.R.

AU - Schlessinger, D.

AU - Schipf, S.

AU - Stumvoll, M.

AU - Tönjes, A.

AU - Spector, T.D.

AU - North, K.E.

AU - Lettre, G.

AU - McCarthy, M.I.

AU - Berndt, S.I.

AU - Heath, A.C.

AU - Madden, P.A.F.

AU - Nyholt, DR

AU - Montgomery, G.W.

AU - Martin, N.G.

AU - McKnight, B.

AU - Strachan, D.P.

AU - Hill, W.G.

AU - Snieder, H.

AU - Ridker, P.M.

AU - Thorsteinsdottir, U.

AU - Stefansson, K.

AU - Frayling, T.M.

AU - Hirschhorn, J.N.

AU - Goddard, M.E.

AU - Visscher, P.M.

PY - 2012

Y1 - 2012

U2 - 10.1038/nature11401

DO - 10.1038/nature11401

M3 - Article

C2 - 22982992

VL - 490

SP - 267

EP - 272

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7419

ER -