Gd-DTPA enhanced MRI in the assessment of myocardial reperfusion

A. De Roos, J. Doornbos, N. Matheijssen, A. Van der Laarse, E. Van der Wall

Research output: Contribution to journalReview articleAcademicpeer-review


Gadolinium DTPA serves as a paramagnetic contrast medium in MR imaging, and has a biodistribution similar to that of the iodinated contrast media used in CT. Its effect is to reduce the T1 and T2 relaxation times, thus increasing the contrast between normally perfused and ischaemic tissue. In this study, Gd-DTPA is used to differentiate between normal and infarcted myocardium, with a view to quantitating the area at risk following coronary artery occlusion, particularly in the first three weeks, and for determining the size of the infarct. The authors conclude that this information may well prove useful for guiding therapeutic interventions and for planning different thrombolytic regimens.

Original languageEnglish
Pages (from-to)99-102
Number of pages4
Issue number3
Publication statusPublished - 1 Dec 1989

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