TY - CHAP
T1 - Genetics: DJ-1 in parkinson’s disease
AU - Heutink, Peter
PY - 2007
Y1 - 2007
N2 - Our genetic knowledge of Parkinson’s disease (PD) is moving forward at an impressive speed. In less than 10 years, family-based linkage analysis and positional cloning have led to the identification of several genes for autosomal recessive PD [PARKIN (1), DJ-1 (2), and PINK-1 (3)], autosomal dominant PD, [a-synuclein (4), UCHL1 (5), NR4A2 (6), and LRRK2 (7,8)] and a number of potential genetic risk factors for idiopathic PD (9).
AB - Our genetic knowledge of Parkinson’s disease (PD) is moving forward at an impressive speed. In less than 10 years, family-based linkage analysis and positional cloning have led to the identification of several genes for autosomal recessive PD [PARKIN (1), DJ-1 (2), and PINK-1 (3)], autosomal dominant PD, [a-synuclein (4), UCHL1 (5), NR4A2 (6), and LRRK2 (7,8)] and a number of potential genetic risk factors for idiopathic PD (9).
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057447002&origin=inward
M3 - Chapter
SN - 9780849336973
T3 - Parkinson's Disease: Genetics and Pathogenesis
SP - 99
EP - 114
BT - Parkinson's Disease: Genetics and Pathogenesis
PB - CRC Press
ER -