Genetics of obsessive-compulsive disorder and tourette disorder

Obsessive Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

Obsessive-compulsive disorder (OCD) and Tourette disorder (TD) are neuropsychiatric disorders in which genetic factors play a substantial, and very often shared, role in both disorders. This chapter reviews the current literature on the genetics of OCD and TD, including genetic epidemiology within and across disorders, familiality, candidate gene studies, genome-wide association studies (GWAS), copy number variants (CNVs), imaging genetics, pharmacogenetics, epigenetics, and gene-environment interaction.

Original languageEnglish
Title of host publicationPersonalized Psychiatry
PublisherElsevier
Pages239-252
Number of pages14
ISBN (Electronic)9780128131763
ISBN (Print)9780128131770
DOIs
Publication statusPublished - 1 Jan 2019

Cite this

Obsessive Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium (2019). Genetics of obsessive-compulsive disorder and tourette disorder. In Personalized Psychiatry (pp. 239-252). Elsevier. https://doi.org/10.1016/B978-0-12-813176-3.00020-1