Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

A. Kottgen; E. Albrecht; A. Teumer; V. Vitart; J. Krumsiek; C. Hundertmark; G. Pistis; D. Ruggiero; C.M. O'Seaghdha; T. Haller; Q. Yang; A.D. Johnson; Z. Kutalik; A.V. Smith; J.L. Shi; M. Struchalin; R.P.S. Middelberg; M.J. Brown; A.L. Gaffo; N. Pirastu; G. Li; C. Hayward; T. Zemunik; J. Huffman; L. Yengo; J.H. Zhao; A. Demirkan; M.F. Feitosa; X. Liu; G. Malerba; L.M. Lopez; P. van der Harst; X.Z. Li; M.E. Kleber; A.A. Hicks; I.M. Nolte; A. Johansson; F. Murgia; S.H. Wild; S.J.L. Bakker; J.F. Peden; A. Dehghan; M. Steri; A. Tenesa; V. Lagou; P. Salo; M. Mangino; L.M. Rose; T. Lehtimaki; O.M. Woodward; Y. Okada; A. Tin; C. Muller; C. Oldmeadow; M. Putku; D. Czamara; P. Kraft; L. Frogheri; G.A. Thun; A. Grotevendt; G.K. Gislason; T.B. Harris; L.J. Launer; P. McArdle; A.R. Shuldiner; E. Boerwinkle; J. Coresh; H. Schmidt; M. Schallert; N.G. Martin; G.W. Montgomery; M. Kubo; Y. Nakamura; T. Tanaka; P.B. Munroe; N.J. Samani; D.R. Jacobs; K. Liu; P. d'Adamo; S. Ulivi; J.I. Rotter; B.M. Psaty; P. Vollenweider; G. Waeber; S. Campbell; O. Devuyst; P. Navarro; I. Kolcic; N. Hastie; B. Balkau; P. Froguel; T. Esko; A. Salumets; K.T. Khaw; C. Langenberg; N.J. Wareham; A. Isaacs; A. Kraja; Q.Y. Zhang; B.W.J.H. Penninx; J.H. Smit; M. Bochud; C. Gieger

doi:10.1038/ng.2500

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

A. Kottgen, E. Albrecht, A. Teumer, V. Vitart, J. Krumsiek, C. Hundertmark, G. Pistis, D. Ruggiero, C.M. O'Seaghdha, T. Haller, Q. Yang, A.D. Johnson, Z. Kutalik, A.V. Smith, J.L. Shi, M. Struchalin, R.P.S. Middelberg, M.J. Brown, A.L. Gaffo, N. PirastuG. Li, C. Hayward, T. Zemunik, J. Huffman, L. Yengo, J.H. Zhao, A. Demirkan, M.F. Feitosa, X. Liu, G. Malerba, L.M. Lopez, P. van der Harst, X.Z. Li, M.E. Kleber, A.A. Hicks, I.M. Nolte, A. Johansson, F. Murgia, S.H. Wild, S.J.L. Bakker, J.F. Peden, A. Dehghan, M. Steri, A. Tenesa, V. Lagou, P. Salo, M. Mangino, L.M. Rose, T. Lehtimaki, O.M. Woodward, Y. Okada, A. Tin, C. Muller, C. Oldmeadow, M. Putku, D. Czamara, P. Kraft, L. Frogheri, G.A. Thun, A. Grotevendt, G.K. Gislason, T.B. Harris, L.J. Launer, P. McArdle, A.R. Shuldiner, E. Boerwinkle, J. Coresh, H. Schmidt, M. Schallert, N.G. Martin, G.W. Montgomery, M. Kubo, Y. Nakamura, T. Tanaka, P.B. Munroe, N.J. Samani, D.R. Jacobs, K. Liu, P. d'Adamo, S. Ulivi, J.I. Rotter, B.M. Psaty, P. Vollenweider, G. Waeber, S. Campbell, O. Devuyst, P. Navarro, I. Kolcic, N. Hastie, B. Balkau, P. Froguel, T. Esko, A. Salumets, K.T. Khaw, C. Langenberg, N.J. Wareham, A. Isaacs, A. Kraja, Q.Y. Zhang, B.W.J.H. Penninx, J.H. Smit, M. Bochud, C. Gieger

Psychiatry

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	145-154
Journal	Nature Genetics
Volume	45
Issue number	2
DOIs	https://doi.org/10.1038/ng.2500
Publication status	Published - 2013

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10.1038/ng.2500

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Kottgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J. L., Struchalin, M., Middelberg, R. P. S., Brown, M. J., Gaffo, A. L., ... Gieger, C. (2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 45(2), 145-154. https://doi.org/10.1038/ng.2500

Kottgen, A. ; Albrecht, E. ; Teumer, A. ; Vitart, V. ; Krumsiek, J. ; Hundertmark, C. ; Pistis, G. ; Ruggiero, D. ; O'Seaghdha, C.M. ; Haller, T. ; Yang, Q. ; Johnson, A.D. ; Kutalik, Z. ; Smith, A.V. ; Shi, J.L. ; Struchalin, M. ; Middelberg, R.P.S. ; Brown, M.J. ; Gaffo, A.L. ; Pirastu, N. ; Li, G. ; Hayward, C. ; Zemunik, T. ; Huffman, J. ; Yengo, L. ; Zhao, J.H. ; Demirkan, A. ; Feitosa, M.F. ; Liu, X. ; Malerba, G. ; Lopez, L.M. ; van der Harst, P. ; Li, X.Z. ; Kleber, M.E. ; Hicks, A.A. ; Nolte, I.M. ; Johansson, A. ; Murgia, F. ; Wild, S.H. ; Bakker, S.J.L. ; Peden, J.F. ; Dehghan, A. ; Steri, M. ; Tenesa, A. ; Lagou, V. ; Salo, P. ; Mangino, M. ; Rose, L.M. ; Lehtimaki, T. ; Woodward, O.M. ; Okada, Y. ; Tin, A. ; Muller, C. ; Oldmeadow, C. ; Putku, M. ; Czamara, D. ; Kraft, P. ; Frogheri, L. ; Thun, G.A. ; Grotevendt, A. ; Gislason, G.K. ; Harris, T.B. ; Launer, L.J. ; McArdle, P. ; Shuldiner, A.R. ; Boerwinkle, E. ; Coresh, J. ; Schmidt, H. ; Schallert, M. ; Martin, N.G. ; Montgomery, G.W. ; Kubo, M. ; Nakamura, Y. ; Tanaka, T. ; Munroe, P.B. ; Samani, N.J. ; Jacobs, D.R. ; Liu, K. ; d'Adamo, P. ; Ulivi, S. ; Rotter, J.I. ; Psaty, B.M. ; Vollenweider, P. ; Waeber, G. ; Campbell, S. ; Devuyst, O. ; Navarro, P. ; Kolcic, I. ; Hastie, N. ; Balkau, B. ; Froguel, P. ; Esko, T. ; Salumets, A. ; Khaw, K.T. ; Langenberg, C. ; Wareham, N.J. ; Isaacs, A. ; Kraja, A. ; Zhang, Q.Y. ; Penninx, B.W.J.H. ; Smit, J.H. ; Bochud, M. ; Gieger, C. / Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. In: Nature Genetics. 2013 ; Vol. 45, No. 2. pp. 145-154.

@article{876feebc93b94229bd99ef14a2ff2225,

title = "Genome-wide association analyses identify 18 new loci associated with serum urate concentrations",

author = "A. Kottgen and E. Albrecht and A. Teumer and V. Vitart and J. Krumsiek and C. Hundertmark and G. Pistis and D. Ruggiero and C.M. O'Seaghdha and T. Haller and Q. Yang and A.D. Johnson and Z. Kutalik and A.V. Smith and J.L. Shi and M. Struchalin and R.P.S. Middelberg and M.J. Brown and A.L. Gaffo and N. Pirastu and G. Li and C. Hayward and T. Zemunik and J. Huffman and L. Yengo and J.H. Zhao and A. Demirkan and M.F. Feitosa and X. Liu and G. Malerba and L.M. Lopez and {van der Harst}, P. and X.Z. Li and M.E. Kleber and A.A. Hicks and I.M. Nolte and A. Johansson and F. Murgia and S.H. Wild and S.J.L. Bakker and J.F. Peden and A. Dehghan and M. Steri and A. Tenesa and V. Lagou and P. Salo and M. Mangino and L.M. Rose and T. Lehtimaki and O.M. Woodward and Y. Okada and A. Tin and C. Muller and C. Oldmeadow and M. Putku and D. Czamara and P. Kraft and L. Frogheri and G.A. Thun and A. Grotevendt and G.K. Gislason and T.B. Harris and L.J. Launer and P. McArdle and A.R. Shuldiner and E. Boerwinkle and J. Coresh and H. Schmidt and M. Schallert and N.G. Martin and G.W. Montgomery and M. Kubo and Y. Nakamura and T. Tanaka and P.B. Munroe and N.J. Samani and D.R. Jacobs and K. Liu and P. d'Adamo and S. Ulivi and J.I. Rotter and B.M. Psaty and P. Vollenweider and G. Waeber and S. Campbell and O. Devuyst and P. Navarro and I. Kolcic and N. Hastie and B. Balkau and P. Froguel and T. Esko and A. Salumets and K.T. Khaw and C. Langenberg and N.J. Wareham and A. Isaacs and A. Kraja and Q.Y. Zhang and B.W.J.H. Penninx and J.H. Smit and M. Bochud and C. Gieger",

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Kottgen, A, Albrecht, E, Teumer, A, Vitart, V, Krumsiek, J, Hundertmark, C, Pistis, G, Ruggiero, D, O'Seaghdha, CM, Haller, T, Yang, Q, Johnson, AD, Kutalik, Z, Smith, AV, Shi, JL, Struchalin, M, Middelberg, RPS, Brown, MJ, Gaffo, AL, Pirastu, N, Li, G, Hayward, C, Zemunik, T, Huffman, J, Yengo, L, Zhao, JH, Demirkan, A, Feitosa, MF, Liu, X, Malerba, G, Lopez, LM, van der Harst, P, Li, XZ, Kleber, ME, Hicks, AA, Nolte, IM, Johansson, A, Murgia, F, Wild, SH, Bakker, SJL, Peden, JF, Dehghan, A, Steri, M, Tenesa, A, Lagou, V, Salo, P, Mangino, M, Rose, LM, Lehtimaki, T, Woodward, OM, Okada, Y, Tin, A, Muller, C, Oldmeadow, C, Putku, M, Czamara, D, Kraft, P, Frogheri, L, Thun, GA, Grotevendt, A, Gislason, GK, Harris, TB, Launer, LJ, McArdle, P, Shuldiner, AR, Boerwinkle, E, Coresh, J, Schmidt, H, Schallert, M, Martin, NG, Montgomery, GW, Kubo, M, Nakamura, Y, Tanaka, T, Munroe, PB, Samani, NJ, Jacobs, DR, Liu, K, d'Adamo, P, Ulivi, S, Rotter, JI, Psaty, BM, Vollenweider, P, Waeber, G, Campbell, S, Devuyst, O, Navarro, P, Kolcic, I, Hastie, N, Balkau, B, Froguel, P, Esko, T, Salumets, A, Khaw, KT, Langenberg, C, Wareham, NJ, Isaacs, A, Kraja, A, Zhang, QY, Penninx, BWJH , Smit, JH, Bochud, M & Gieger, C 2013, 'Genome-wide association analyses identify 18 new loci associated with serum urate concentrations', Nature Genetics, vol. 45, no. 2, pp. 145-154. https://doi.org/10.1038/ng.2500

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. / Kottgen, A.; Albrecht, E.; Teumer, A.; Vitart, V.; Krumsiek, J.; Hundertmark, C.; Pistis, G.; Ruggiero, D.; O'Seaghdha, C.M.; Haller, T.; Yang, Q.; Johnson, A.D.; Kutalik, Z.; Smith, A.V.; Shi, J.L.; Struchalin, M.; Middelberg, R.P.S.; Brown, M.J.; Gaffo, A.L.; Pirastu, N.; Li, G.; Hayward, C.; Zemunik, T.; Huffman, J.; Yengo, L.; Zhao, J.H.; Demirkan, A.; Feitosa, M.F.; Liu, X.; Malerba, G.; Lopez, L.M.; van der Harst, P.; Li, X.Z.; Kleber, M.E.; Hicks, A.A.; Nolte, I.M.; Johansson, A.; Murgia, F.; Wild, S.H.; Bakker, S.J.L.; Peden, J.F.; Dehghan, A.; Steri, M.; Tenesa, A.; Lagou, V.; Salo, P.; Mangino, M.; Rose, L.M.; Lehtimaki, T.; Woodward, O.M.; Okada, Y.; Tin, A.; Muller, C.; Oldmeadow, C.; Putku, M.; Czamara, D.; Kraft, P.; Frogheri, L.; Thun, G.A.; Grotevendt, A.; Gislason, G.K.; Harris, T.B.; Launer, L.J.; McArdle, P.; Shuldiner, A.R.; Boerwinkle, E.; Coresh, J.; Schmidt, H.; Schallert, M.; Martin, N.G.; Montgomery, G.W.; Kubo, M.; Nakamura, Y.; Tanaka, T.; Munroe, P.B.; Samani, N.J.; Jacobs, D.R.; Liu, K.; d'Adamo, P.; Ulivi, S.; Rotter, J.I.; Psaty, B.M.; Vollenweider, P.; Waeber, G.; Campbell, S.; Devuyst, O.; Navarro, P.; Kolcic, I.; Hastie, N.; Balkau, B.; Froguel, P.; Esko, T.; Salumets, A.; Khaw, K.T.; Langenberg, C.; Wareham, N.J.; Isaacs, A.; Kraja, A.; Zhang, Q.Y.; Penninx, B.W.J.H.; Smit, J.H.; Bochud, M.; Gieger, C.

In: Nature Genetics, Vol. 45, No. 2, 2013, p. 145-154.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

AU - Kottgen, A.

AU - Albrecht, E.

AU - Teumer, A.

AU - Vitart, V.

AU - Krumsiek, J.

AU - Hundertmark, C.

AU - Pistis, G.

AU - Ruggiero, D.

AU - O'Seaghdha, C.M.

AU - Haller, T.

AU - Yang, Q.

AU - Johnson, A.D.

AU - Kutalik, Z.

AU - Smith, A.V.

AU - Shi, J.L.

AU - Struchalin, M.

AU - Middelberg, R.P.S.

AU - Brown, M.J.

AU - Gaffo, A.L.

AU - Pirastu, N.

AU - Li, G.

AU - Hayward, C.

AU - Zemunik, T.

AU - Huffman, J.

AU - Yengo, L.

AU - Zhao, J.H.

AU - Demirkan, A.

AU - Feitosa, M.F.

AU - Liu, X.

AU - Malerba, G.

AU - Lopez, L.M.

AU - van der Harst, P.

AU - Li, X.Z.

AU - Kleber, M.E.

AU - Hicks, A.A.

AU - Nolte, I.M.

AU - Johansson, A.

AU - Murgia, F.

AU - Wild, S.H.

AU - Bakker, S.J.L.

AU - Peden, J.F.

AU - Dehghan, A.

AU - Steri, M.

AU - Tenesa, A.

AU - Lagou, V.

AU - Salo, P.

AU - Mangino, M.

AU - Rose, L.M.

AU - Lehtimaki, T.

AU - Woodward, O.M.

AU - Okada, Y.

AU - Tin, A.

AU - Muller, C.

AU - Oldmeadow, C.

AU - Putku, M.

AU - Czamara, D.

AU - Kraft, P.

AU - Frogheri, L.

AU - Thun, G.A.

AU - Grotevendt, A.

AU - Gislason, G.K.

AU - Harris, T.B.

AU - Launer, L.J.

AU - McArdle, P.

AU - Shuldiner, A.R.

AU - Boerwinkle, E.

AU - Coresh, J.

AU - Schmidt, H.

AU - Schallert, M.

AU - Martin, N.G.

AU - Montgomery, G.W.

AU - Kubo, M.

AU - Nakamura, Y.

AU - Tanaka, T.

AU - Munroe, P.B.

AU - Samani, N.J.

AU - Jacobs, D.R.

AU - Liu, K.

AU - d'Adamo, P.

AU - Ulivi, S.

AU - Rotter, J.I.

AU - Psaty, B.M.

AU - Vollenweider, P.

AU - Waeber, G.

AU - Campbell, S.

AU - Devuyst, O.

AU - Navarro, P.

AU - Kolcic, I.

AU - Hastie, N.

AU - Balkau, B.

AU - Froguel, P.

AU - Esko, T.

AU - Salumets, A.

AU - Khaw, K.T.

AU - Langenberg, C.

AU - Wareham, N.J.

AU - Isaacs, A.

AU - Kraja, A.

AU - Zhang, Q.Y.

AU - Penninx, B.W.J.H.

AU - Smit, J.H.

AU - Bochud, M.

AU - Gieger, C.

PY - 2013

Y1 - 2013

U2 - 10.1038/ng.2500

DO - 10.1038/ng.2500

M3 - Article

C2 - 23263486

VL - 45

SP - 145

EP - 154

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 2

ER -