Haemolytic anaemia after nitrofurantoin treatment in a pregnant woman with G6PD deficiency

Lidewij van de Mheen, Simone M Smits, Wim E Terpstra, Anja Leyte, Dick J Bekedam, Eline S A van den Akker

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We present a normotensive, pregnant woman with severe haemolytic anaemia in the third trimester of pregnancy. Owing to normal platelet count diagnoses other than HELLP syndrome were considered and investigated. The patient was treated with nitrofurantoin 3 weeks before presentation and she turned out to have a deficiency of glucose-6-phosphate dehydrogenase. After treatment with blood transfusion, vitamin B12 and folic acid the patient recovered completely. Caesarean delivery was performed because of maternal hypertension and fetal distress at 33 weeks' gestation.

Original languageEnglish
JournalBMJ Case Reports
Publication statusPublished - 30 Apr 2014

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