### Abstract

Left ventricular interaction with arterial load has been described in terms of the ratio (k) of effective arterial elastance (Ea) and maximal systolic elastance (Emax). Using the definition formulas for both elastances, a linear relationship between end-systolic volume (ESV) and end-diastolic volume (EDV) can be derived. The slope of this linearity equals k/(k+1), while the intercept can be identified as Vo/(k+1) where Vo is the extrapolated volume intercept of the linearized Emax-concept. Since the ESV vs EDV relationship refers to ventricular volume regulation, we have demonstrated that its characteristics can be exclusively expressed in terms of the coupling index k and the intercept Vo. We conclude that k and Vo are important determinants of the regulation of ventricular volume.

Original language | English |
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Pages | 1213-1214 |

Number of pages | 2 |

Publication status | Published - 1 Dec 2002 |

Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: 23 Oct 2002 → 26 Oct 2002 |

### Conference

Conference | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) |
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Country | United States |

City | Houston, TX |

Period | 23/10/2002 → 26/10/2002 |

### Cite this

*Identification of left ventricular volume regulation on the basis of the elastance concept*. 1213-1214. Paper presented at Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States.

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**Identification of left ventricular volume regulation on the basis of the elastance concept.** / Kerkhof, Peter L M; Li, John K J.

Research output: Contribution to conference › Paper › Academic

TY - CONF

T1 - Identification of left ventricular volume regulation on the basis of the elastance concept

AU - Kerkhof, Peter L M

AU - Li, John K J

PY - 2002/12/1

Y1 - 2002/12/1

N2 - Left ventricular interaction with arterial load has been described in terms of the ratio (k) of effective arterial elastance (Ea) and maximal systolic elastance (Emax). Using the definition formulas for both elastances, a linear relationship between end-systolic volume (ESV) and end-diastolic volume (EDV) can be derived. The slope of this linearity equals k/(k+1), while the intercept can be identified as Vo/(k+1) where Vo is the extrapolated volume intercept of the linearized Emax-concept. Since the ESV vs EDV relationship refers to ventricular volume regulation, we have demonstrated that its characteristics can be exclusively expressed in terms of the coupling index k and the intercept Vo. We conclude that k and Vo are important determinants of the regulation of ventricular volume.

AB - Left ventricular interaction with arterial load has been described in terms of the ratio (k) of effective arterial elastance (Ea) and maximal systolic elastance (Emax). Using the definition formulas for both elastances, a linear relationship between end-systolic volume (ESV) and end-diastolic volume (EDV) can be derived. The slope of this linearity equals k/(k+1), while the intercept can be identified as Vo/(k+1) where Vo is the extrapolated volume intercept of the linearized Emax-concept. Since the ESV vs EDV relationship refers to ventricular volume regulation, we have demonstrated that its characteristics can be exclusively expressed in terms of the coupling index k and the intercept Vo. We conclude that k and Vo are important determinants of the regulation of ventricular volume.

UR - http://www.scopus.com/inward/record.url?scp=0036916238&partnerID=8YFLogxK

M3 - Paper

SP - 1213

EP - 1214

ER -