Immunology and barrier function of the skin

Thomas Rustemeyer*, Manigé Fartasch

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Abstract

A disturbed epidermal barrier may lead to irritant contact dermatitis. An enhanced penetration through skin barrier may facilitate sensitization. Immunological effects induced by pre-irritation and barrier alteration may further lead to the induction of allergic Type IV-contact dermatitis and Type I (immediate-type reaction) reactions or aggravate allergic reactions.

Original languageEnglish
Title of host publicationKanerva's Occupational Dermatology
PublisherSpringer International Publishing AG
Pages3-10
Number of pages8
ISBN (Electronic)9783319686172
ISBN (Print)9783319686158
DOIs
Publication statusPublished - 1 Jan 2019

Cite this

Rustemeyer, T., & Fartasch, M. (2019). Immunology and barrier function of the skin. In Kanerva's Occupational Dermatology (pp. 3-10). Springer International Publishing AG. https://doi.org/10.1007/978-3-319-68617-2_1