In genes we trust versus het gen voorbij: Over schizofrenie

Translated title of the contribution: In genes we trust versus beyond the gene. About schizophrenia

J. C. Van Der Stel*

*Corresponding author for this work

Research output: Contribution to journalReview articleProfessional

Abstract

The determinants and disease mechanisms of schizophrenia are largely unknown. This article discusses two genetic and two epigenetic models and examines to what extent they are capable of predicting epidemiological patterns, providing insight into the determinants and disease mechanisms, and to what extent they are based on empirical findings. The proposed litmus test is whether they are able to provide an explanation for discordance in monozygotic twins. The main lines of a synthetic model are presented on the basis of the assessments.

Translated title of the contributionIn genes we trust versus beyond the gene. About schizophrenia
Original languageDutch
Pages (from-to)813-822
Number of pages10
JournalTijdschrift voor Psychiatrie
Volume49
Issue number11
Publication statusPublished - 2007

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