Incidence of refeeding syndrome in internal medicine patients: Netherlands Journal of Medicine

B. V. C. Kraaijenbrink, W. M. Lambers, E.H.M. Mathus Vliegen, Carl E. H. Siegert

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Refeeding syndrome is a potentially fatal shift of fluids and electrolytes that may occur after reintroducing nutrition in a malnourished patient. Its incidence in internal medicine patients is not known. We aimed at determining the incidence in a heterogeneous group of patients acutely admitted to a department of internal medicine. Methods: All patients acutely admitted to the department of internal medicine of a teaching community hospital in Amsterdam, the Netherlands, between 22 February 2011 and 29 April 2011, were included. We applied the National Institute for Health and Care Excellence ( NICE) criteria for determining people at risk of refeeding syndrome and took hypophosphataemia as the main indicator for the presence of this syndrome. Results: Of 178 patients included in the study, 97 (54%) were considered to be at risk of developing refeeding syndrome and 14 patients actually developed the syndrome (14% of patients at risk and 8% of study population). Patients with a malignancy or previous malignancy were at increased risk of developing refeeding syndrome (p <0.05). Measurement of muscle strength over time was not associated with the occurrence of refeeding syndrome. The Short Nutritional Assessment Questionnaire score had a positive and negative predictive value of 13% and 95% respectively. Conclusion: The incidence of refeeding syndrome was relatively high in patients acutely admitted to the department of internal medicine. Oncology patients are at increased risk of developing refeeding syndrome. When taking the occurrence of hypophosphataemia as a hallmark, no other single clinical or composite parameter could be identified that accurately predicts the development of refeeding syndrome.
Original languageEnglish
Pages (from-to)116-121
Number of pages6
JournalNetherlands Journal of Medicine
Volume74
Publication statusPublished - 2016

Cite this

Kraaijenbrink, B. V. C., Lambers, W. M., Mathus Vliegen, E. H. M., & Siegert, C. E. H. (2016). Incidence of refeeding syndrome in internal medicine patients: Netherlands Journal of Medicine. Netherlands Journal of Medicine, 74, 116-121.
Kraaijenbrink, B. V. C. ; Lambers, W. M. ; Mathus Vliegen, E.H.M. ; Siegert, Carl E. H. / Incidence of refeeding syndrome in internal medicine patients : Netherlands Journal of Medicine. In: Netherlands Journal of Medicine. 2016 ; Vol. 74. pp. 116-121.
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abstract = "Background: Refeeding syndrome is a potentially fatal shift of fluids and electrolytes that may occur after reintroducing nutrition in a malnourished patient. Its incidence in internal medicine patients is not known. We aimed at determining the incidence in a heterogeneous group of patients acutely admitted to a department of internal medicine. Methods: All patients acutely admitted to the department of internal medicine of a teaching community hospital in Amsterdam, the Netherlands, between 22 February 2011 and 29 April 2011, were included. We applied the National Institute for Health and Care Excellence ( NICE) criteria for determining people at risk of refeeding syndrome and took hypophosphataemia as the main indicator for the presence of this syndrome. Results: Of 178 patients included in the study, 97 (54{\%}) were considered to be at risk of developing refeeding syndrome and 14 patients actually developed the syndrome (14{\%} of patients at risk and 8{\%} of study population). Patients with a malignancy or previous malignancy were at increased risk of developing refeeding syndrome (p <0.05). Measurement of muscle strength over time was not associated with the occurrence of refeeding syndrome. The Short Nutritional Assessment Questionnaire score had a positive and negative predictive value of 13{\%} and 95{\%} respectively. Conclusion: The incidence of refeeding syndrome was relatively high in patients acutely admitted to the department of internal medicine. Oncology patients are at increased risk of developing refeeding syndrome. When taking the occurrence of hypophosphataemia as a hallmark, no other single clinical or composite parameter could be identified that accurately predicts the development of refeeding syndrome.",
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Kraaijenbrink, BVC, Lambers, WM, Mathus Vliegen, EHM & Siegert, CEH 2016, 'Incidence of refeeding syndrome in internal medicine patients: Netherlands Journal of Medicine' Netherlands Journal of Medicine, vol. 74, pp. 116-121.

Incidence of refeeding syndrome in internal medicine patients : Netherlands Journal of Medicine. / Kraaijenbrink, B. V. C.; Lambers, W. M.; Mathus Vliegen, E.H.M.; Siegert, Carl E. H.

In: Netherlands Journal of Medicine, Vol. 74, 2016, p. 116-121.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Incidence of refeeding syndrome in internal medicine patients

T2 - Netherlands Journal of Medicine

AU - Kraaijenbrink, B. V. C.

AU - Lambers, W. M.

AU - Mathus Vliegen, E.H.M.

AU - Siegert, Carl E. H.

N1 - M1 - 3 ISI Document Delivery No.: DP0AN Times Cited: 0 Cited Reference Count: 26 Kraaijenbrink, B. V. C. Lambers, W. M. Mathus-Vliegen, E. M. H. Siegert, C. E. H. 0 3 4 VAN ZUIDEN COMMUNICATIONS ALPHEN AAN DE RIJN NETH J MED

PY - 2016

Y1 - 2016

N2 - Background: Refeeding syndrome is a potentially fatal shift of fluids and electrolytes that may occur after reintroducing nutrition in a malnourished patient. Its incidence in internal medicine patients is not known. We aimed at determining the incidence in a heterogeneous group of patients acutely admitted to a department of internal medicine. Methods: All patients acutely admitted to the department of internal medicine of a teaching community hospital in Amsterdam, the Netherlands, between 22 February 2011 and 29 April 2011, were included. We applied the National Institute for Health and Care Excellence ( NICE) criteria for determining people at risk of refeeding syndrome and took hypophosphataemia as the main indicator for the presence of this syndrome. Results: Of 178 patients included in the study, 97 (54%) were considered to be at risk of developing refeeding syndrome and 14 patients actually developed the syndrome (14% of patients at risk and 8% of study population). Patients with a malignancy or previous malignancy were at increased risk of developing refeeding syndrome (p <0.05). Measurement of muscle strength over time was not associated with the occurrence of refeeding syndrome. The Short Nutritional Assessment Questionnaire score had a positive and negative predictive value of 13% and 95% respectively. Conclusion: The incidence of refeeding syndrome was relatively high in patients acutely admitted to the department of internal medicine. Oncology patients are at increased risk of developing refeeding syndrome. When taking the occurrence of hypophosphataemia as a hallmark, no other single clinical or composite parameter could be identified that accurately predicts the development of refeeding syndrome.

AB - Background: Refeeding syndrome is a potentially fatal shift of fluids and electrolytes that may occur after reintroducing nutrition in a malnourished patient. Its incidence in internal medicine patients is not known. We aimed at determining the incidence in a heterogeneous group of patients acutely admitted to a department of internal medicine. Methods: All patients acutely admitted to the department of internal medicine of a teaching community hospital in Amsterdam, the Netherlands, between 22 February 2011 and 29 April 2011, were included. We applied the National Institute for Health and Care Excellence ( NICE) criteria for determining people at risk of refeeding syndrome and took hypophosphataemia as the main indicator for the presence of this syndrome. Results: Of 178 patients included in the study, 97 (54%) were considered to be at risk of developing refeeding syndrome and 14 patients actually developed the syndrome (14% of patients at risk and 8% of study population). Patients with a malignancy or previous malignancy were at increased risk of developing refeeding syndrome (p <0.05). Measurement of muscle strength over time was not associated with the occurrence of refeeding syndrome. The Short Nutritional Assessment Questionnaire score had a positive and negative predictive value of 13% and 95% respectively. Conclusion: The incidence of refeeding syndrome was relatively high in patients acutely admitted to the department of internal medicine. Oncology patients are at increased risk of developing refeeding syndrome. When taking the occurrence of hypophosphataemia as a hallmark, no other single clinical or composite parameter could be identified that accurately predicts the development of refeeding syndrome.

M3 - Article

VL - 74

SP - 116

EP - 121

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

SN - 0300-2977

ER -

Kraaijenbrink BVC, Lambers WM, Mathus Vliegen EHM, Siegert CEH. Incidence of refeeding syndrome in internal medicine patients: Netherlands Journal of Medicine. Netherlands Journal of Medicine. 2016;74:116-121.