TY - JOUR
T1 - Increased affective reactivity among depressed individuals can be explained by floor effects
T2 - An experience sampling study
AU - von Klipstein, Lino
AU - Servaas, Michelle N.
AU - Lamers, Femke
AU - Schoevers, Robert A.
AU - Wardenaar, Klaas J.
AU - Riese, Harriëtte
N1 - Funding Information:
This work was supported by the charitable foundation Stichting tot Steun VCVGZ (awarded to HR, grant 239 ) and the foundation Researchfonds Stichting Postacademische Psy-opleidingen (awarded to MNS, grant PPO-MS-MH ). The infrastructure for the NESDA study ( www.nesda.nl ) has been funded through the Geestkracht program of the Netherlands Organisation for Health Research and Development (ZonMw, grant number 10-000-1002 ) and by participating universities and mental health care organizations ( Amsterdam University Medical Centers (location VUmc), GGZ inGeest , Leiden University Medical Center , University Medical Center Groningen , University of Groningen , Lentis , GGZ Friesland , GGZ Drenthe , Dimence Groep , Rob Giel Onderzoekcentrum ).
Publisher Copyright:
© 2023 The Authors
PY - 2023/8/1
Y1 - 2023/8/1
N2 - Experience sampling studies into daily-life affective reactivity indicate that depressed individuals react more strongly to both positive and negative stimuli than non-depressed individuals, particularly on negative affect (NA). Given the different mean levels of both positive affect (PA) and NA between patients and controls, such findings may be influenced by floor/ceiling effects, leading to violations of the normality and homoscedasticity assumptions underlying the used statistical models. Affect distributions in prior studies suggest that this may have particularly influenced NA-reactivity findings. Here, we investigated the influence of floor/ceiling effects on the observed PA- and NA-reactivity to both positive and negative events. Data came from 346 depressed, non-depressed, and remitted participants from the Netherlands Study of Depression and Anxiety (NESDA). In PA-reactivity analyses, no floor/ceiling effects and assumption violations were observed, and PA-reactivity to positive events, but not negative events, was significantly increased in the depressed and remitted groups versus the non-depressed group. However, NA-scores exhibited a floor effect in the non-depressed group and naively estimated models violated model assumptions. When these violations were accounted for in subsequent analyses, group differences in NA-reactivity that had been present in the naive models were no longer observed. In conclusion, we found increased PA-reactivity to positive events but no evidence of increased NA-reactivity in depressed individuals when accounting for violations of assumptions. The results indicate that affective-reactivity results are very sensitive to modeling choices and that previously observed increased NA-reactivity in depressed individuals may (partially) reflect unaddressed assumption violations resulting from floor effects in NA.
AB - Experience sampling studies into daily-life affective reactivity indicate that depressed individuals react more strongly to both positive and negative stimuli than non-depressed individuals, particularly on negative affect (NA). Given the different mean levels of both positive affect (PA) and NA between patients and controls, such findings may be influenced by floor/ceiling effects, leading to violations of the normality and homoscedasticity assumptions underlying the used statistical models. Affect distributions in prior studies suggest that this may have particularly influenced NA-reactivity findings. Here, we investigated the influence of floor/ceiling effects on the observed PA- and NA-reactivity to both positive and negative events. Data came from 346 depressed, non-depressed, and remitted participants from the Netherlands Study of Depression and Anxiety (NESDA). In PA-reactivity analyses, no floor/ceiling effects and assumption violations were observed, and PA-reactivity to positive events, but not negative events, was significantly increased in the depressed and remitted groups versus the non-depressed group. However, NA-scores exhibited a floor effect in the non-depressed group and naively estimated models violated model assumptions. When these violations were accounted for in subsequent analyses, group differences in NA-reactivity that had been present in the naive models were no longer observed. In conclusion, we found increased PA-reactivity to positive events but no evidence of increased NA-reactivity in depressed individuals when accounting for violations of assumptions. The results indicate that affective-reactivity results are very sensitive to modeling choices and that previously observed increased NA-reactivity in depressed individuals may (partially) reflect unaddressed assumption violations resulting from floor effects in NA.
KW - Bounded measurement
KW - Ecological momentary assessment
KW - Emotional reactivity
KW - Major Depressive Disorder
KW - Stress reactivity
UR - http://www.scopus.com/inward/record.url?scp=85158905374&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2023.04.118
DO - 10.1016/j.jad.2023.04.118
M3 - Article
C2 - 37150221
SN - 0165-0327
VL - 334
SP - 370
EP - 381
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -