Influence of anthropometric parameters and bone size on bone mineral density using volumetric quantitative computed tomography and dual X-ray absorptiometry at the hip

G Guglielmi, C van Kuijk, J. Li, M D Meta, A Scillitani, Thomas F. Lang

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

PURPOSE: To evaluate the influence of anthropometric parameters (age, height, and weight) and bone size on bone mineral density (BMD) using volumetric quantitative computed tomography (QCT) and dual X-ray absorptiometry (DXA) in a group of elderly women.

MATERIAL AND METHODS: BMD values were obtained with DXA and QCT at the spine and hip in a cohort of 84 elderly women (mean age 73 +/- 6 years). QCT measures included trabecular, integral, and cortical BMD assessed at the hip and spine as well as cross-sectional areas of the mid-vertebrae and proximal femora. Spinal integral and femoral neck BMD measures were well matched to the regions of bone quantified on anteroposterior (AP) spine DXA and the femoral neck region of hip DXA.

RESULTS: When QCT parameters were linearly regressed against body height and weight, only the relationships with weight were found to be statistically significant. Except for cortical BMD at the femoral neck, all BMD and geometric parameters measured from both DXA and QCT showed statistically significant associations with body weight (r2 = 0.4, 0.0001 < P < 0.02). The strongest associations with weight were found for DXA Neck (DXA_NECK) and DXA lumbar spine (DXA_LSP) (r2 = 0.4, P < 0.0001).

CONCLUSION: The relationship of DXA BMD is stronger than QCT BMD with body weight and it encompasses the response of both bone size and density to increasing body mass.

Original languageEnglish
Pages (from-to)574-80
Number of pages7
JournalActa Radiologica
Volume47
Issue number6
Publication statusPublished - Jul 2006

Cite this

@article{2d118314d1d048c8a3b0939d7f6fcc5d,
title = "Influence of anthropometric parameters and bone size on bone mineral density using volumetric quantitative computed tomography and dual X-ray absorptiometry at the hip",
abstract = "PURPOSE: To evaluate the influence of anthropometric parameters (age, height, and weight) and bone size on bone mineral density (BMD) using volumetric quantitative computed tomography (QCT) and dual X-ray absorptiometry (DXA) in a group of elderly women.MATERIAL AND METHODS: BMD values were obtained with DXA and QCT at the spine and hip in a cohort of 84 elderly women (mean age 73 +/- 6 years). QCT measures included trabecular, integral, and cortical BMD assessed at the hip and spine as well as cross-sectional areas of the mid-vertebrae and proximal femora. Spinal integral and femoral neck BMD measures were well matched to the regions of bone quantified on anteroposterior (AP) spine DXA and the femoral neck region of hip DXA.RESULTS: When QCT parameters were linearly regressed against body height and weight, only the relationships with weight were found to be statistically significant. Except for cortical BMD at the femoral neck, all BMD and geometric parameters measured from both DXA and QCT showed statistically significant associations with body weight (r2 = 0.4, 0.0001 < P < 0.02). The strongest associations with weight were found for DXA Neck (DXA_NECK) and DXA lumbar spine (DXA_LSP) (r2 = 0.4, P < 0.0001).CONCLUSION: The relationship of DXA BMD is stronger than QCT BMD with body weight and it encompasses the response of both bone size and density to increasing body mass.",
keywords = "Absorptiometry, Photon, Age Factors, Aged, Anatomy, Cross-Sectional, Anthropometry, Body Height, Body Mass Index, Body Weight, Bone Density, Cohort Studies, Female, Femur, Femur Neck, Hip Joint, Humans, Imaging, Three-Dimensional, Lumbar Vertebrae, Spinal Fractures, Spine, Thoracic Vertebrae, Tomography, Spiral Computed, Tomography, X-Ray Computed, Journal Article",
author = "G Guglielmi and {van Kuijk}, C and J. Li and Meta, {M D} and A Scillitani and Lang, {Thomas F.}",
year = "2006",
month = "7",
language = "English",
volume = "47",
pages = "574--80",
journal = "Acta Radiologica",
issn = "0284-1851",
publisher = "SAGE Publications Ltd",
number = "6",

}

Influence of anthropometric parameters and bone size on bone mineral density using volumetric quantitative computed tomography and dual X-ray absorptiometry at the hip. / Guglielmi, G; van Kuijk, C; Li, J.; Meta, M D; Scillitani, A; Lang, Thomas F.

In: Acta Radiologica, Vol. 47, No. 6, 07.2006, p. 574-80.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Influence of anthropometric parameters and bone size on bone mineral density using volumetric quantitative computed tomography and dual X-ray absorptiometry at the hip

AU - Guglielmi, G

AU - van Kuijk, C

AU - Li, J.

AU - Meta, M D

AU - Scillitani, A

AU - Lang, Thomas F.

PY - 2006/7

Y1 - 2006/7

N2 - PURPOSE: To evaluate the influence of anthropometric parameters (age, height, and weight) and bone size on bone mineral density (BMD) using volumetric quantitative computed tomography (QCT) and dual X-ray absorptiometry (DXA) in a group of elderly women.MATERIAL AND METHODS: BMD values were obtained with DXA and QCT at the spine and hip in a cohort of 84 elderly women (mean age 73 +/- 6 years). QCT measures included trabecular, integral, and cortical BMD assessed at the hip and spine as well as cross-sectional areas of the mid-vertebrae and proximal femora. Spinal integral and femoral neck BMD measures were well matched to the regions of bone quantified on anteroposterior (AP) spine DXA and the femoral neck region of hip DXA.RESULTS: When QCT parameters were linearly regressed against body height and weight, only the relationships with weight were found to be statistically significant. Except for cortical BMD at the femoral neck, all BMD and geometric parameters measured from both DXA and QCT showed statistically significant associations with body weight (r2 = 0.4, 0.0001 < P < 0.02). The strongest associations with weight were found for DXA Neck (DXA_NECK) and DXA lumbar spine (DXA_LSP) (r2 = 0.4, P < 0.0001).CONCLUSION: The relationship of DXA BMD is stronger than QCT BMD with body weight and it encompasses the response of both bone size and density to increasing body mass.

AB - PURPOSE: To evaluate the influence of anthropometric parameters (age, height, and weight) and bone size on bone mineral density (BMD) using volumetric quantitative computed tomography (QCT) and dual X-ray absorptiometry (DXA) in a group of elderly women.MATERIAL AND METHODS: BMD values were obtained with DXA and QCT at the spine and hip in a cohort of 84 elderly women (mean age 73 +/- 6 years). QCT measures included trabecular, integral, and cortical BMD assessed at the hip and spine as well as cross-sectional areas of the mid-vertebrae and proximal femora. Spinal integral and femoral neck BMD measures were well matched to the regions of bone quantified on anteroposterior (AP) spine DXA and the femoral neck region of hip DXA.RESULTS: When QCT parameters were linearly regressed against body height and weight, only the relationships with weight were found to be statistically significant. Except for cortical BMD at the femoral neck, all BMD and geometric parameters measured from both DXA and QCT showed statistically significant associations with body weight (r2 = 0.4, 0.0001 < P < 0.02). The strongest associations with weight were found for DXA Neck (DXA_NECK) and DXA lumbar spine (DXA_LSP) (r2 = 0.4, P < 0.0001).CONCLUSION: The relationship of DXA BMD is stronger than QCT BMD with body weight and it encompasses the response of both bone size and density to increasing body mass.

KW - Absorptiometry, Photon

KW - Age Factors

KW - Aged

KW - Anatomy, Cross-Sectional

KW - Anthropometry

KW - Body Height

KW - Body Mass Index

KW - Body Weight

KW - Bone Density

KW - Cohort Studies

KW - Female

KW - Femur

KW - Femur Neck

KW - Hip Joint

KW - Humans

KW - Imaging, Three-Dimensional

KW - Lumbar Vertebrae

KW - Spinal Fractures

KW - Spine

KW - Thoracic Vertebrae

KW - Tomography, Spiral Computed

KW - Tomography, X-Ray Computed

KW - Journal Article

M3 - Article

VL - 47

SP - 574

EP - 580

JO - Acta Radiologica

JF - Acta Radiologica

SN - 0284-1851

IS - 6

ER -