Insulineallergie; achtergrond, diagnostiek en behandeling

Translated title of the contribution: Insulin allergy: Background, diagnostics and treatment

J. Wonders, E. M.W. Eekhoff, R. Heine, D. P. Bruynzeel, T. Rustemeyer*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

An allergic reaction develops in 2.4% of patients that use insulin. This ranges in severity from erythema and pruritus to life-threatening anaphylaxis. Allergic reactions to insulin usually occur within a few hours after an injection and are usually due to a local or systemic type I IgE-mediated hypersensitivity reaction. Despite considerable research into the immunogenicity of insulin, this has not yet been clarified completely and allergic reactions to insulin still occur. A systematic diagnostic approach is essential for an adequate treatment plan. A blood test for anti-insulin antibodies and intradermal skin tests are of great importance. There are many options available for the treatment of insulin allergy and each patient must therefore be evaluated individually.

Translated title of the contributionInsulin allergy: Background, diagnostics and treatment
Original languageDutch
Pages (from-to)2783-2788
Number of pages6
JournalNederlands Tijdschrift voor Geneeskunde
Volume149
Issue number50
Publication statusPublished - 10 Dec 2005

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