Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects

Graziano Onder, Silvia Giovannini, Federica Sganga, Ester Manes-Gravina, Eva Topinkova, Harriet Finne-Soveri, Vjenka Garms-Homolová, Anja Declercq, Henriëtte G. van der Roest, P. lmi V. Jónsson, Hein van Hout, Roberto Bernabei

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Aim: Drugs may interact with geriatric syndromes by playing a role in the continuation, recurrence or worsening of these conditions. Aim of this study is to assess the prevalence of interactions between drugs and three common geriatric syndromes (delirium, falls and urinary incontinence) among older adults in nursing home and home care in Europe. Methods: We performed a cross-sectional multicenter study among 4023 nursing home residents participating in the Services and Health for Elderly in Long-TERm care (Shelter) project and 1469 home care patients participating in the Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care (IBenC) project. Exposure to interactions between drugs and geriatric syndromes was assessed by 2015 Beers criteria. Results: 790/4023 (19.6%) residents in the Shelter Project and 179/1469 (12.2%) home care patients in the IBenC Project presented with one or more drug interactions with geriatric syndromes. In the Shelter project, 288/373 (77.2%) residents experiencing a fall, 429/659 (65.1%) presenting with delirium and 180/2765 (6.5%) with urinary incontinence were on one or more interacting drugs. In the IBenC project, 78/172 (45.3%) participants experiencing a fall, 80/182 (44.0%) presenting with delirium and 36/504 (7.1%) with urinary incontinence were on one or more interacting drugs. Conclusion: Drug–geriatric syndromes interactions are common in long-term care patients. Future studies and interventions aimed at improving pharmacological prescription in the long-term care setting should assess not only drug–drug and drug–disease interactions, but also interactions involving geriatric syndromes.
Original languageEnglish
Pages (from-to)1015-1021
JournalAging Clinical and Experimental Research
Volume30
Issue number9
DOIs
Publication statusPublished - 2018

Cite this

Onder, G., Giovannini, S., Sganga, F., Manes-Gravina, E., Topinkova, E., Finne-Soveri, H., ... Bernabei, R. (2018). Interactions between drugs and geriatric syndromes in nursing home and home care: results from Shelter and IBenC projects. Aging Clinical and Experimental Research, 30(9), 1015-1021. https://doi.org/10.1007/s40520-018-0893-1