Isoenzymes of vitamin-K-dependent carboxylase

Magda M.W. Ulrich*, Berry A.M. Soute, Marian A.G. de Boer-van den Berg, Cees Vermeer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Vitamin-K-dependent carboxylase was prepared from bovine liver, kidney, lung and testis and it was checked that these systems obeyed the laws of normal enzyme kinetics. Four carboxylatable substrates were obtained from different sources and the apparent Michaelis constants of the various carboxylase for these four substrates were measured. From the results thus obrained we conclude that carboxylase is a group name for a number of isoenzymes which are present in heaptic as well as in various non-hepatic tissues.

Original languageEnglish
Pages (from-to)105-108
Number of pages4
JournalBiochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
Issue number1
Publication statusPublished - 18 Jul 1985

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