Laser-assisted endoscopic third ventriculostomy: long-term results in a series of 202 patients

Janneke van Beijnum, Patrick W Hanlo, Kathelijn Fischer, Mohsen M Majidpour, Marlous F Kortekaas, Rudolf M Verdaasdonk, W Peter Vandertop

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: Endoscopic third ventriculostomy is a well-known surgical option in the treatment of noncommunicating hydrocephalus. We studied complications and long-term success in 202 patients to demonstrate the safety and efficacy of laser-assisted endoscopic third ventriculostomy (LA-ETV) using a unique "black" fiber tip/diode laser combination for controlled tissue ablation.

METHODS: We studied 213 LA-ETVs, which were performed in 202 patients. Patients' ages ranged from 2 days to 83 years (mean age, 27 yr). The mean follow-up period for all patients was 2.7 years (range, 2 d to 12 yr). Hydrocephalus was caused by aqueductal stenosis in 65 patients, tumors in 67 patients, hemorrhages in 24 patients, myelomeningoceles in 20 patients, cysts in 15 patients, and other causes in 11 patients. The long-term effectiveness of LA-ETV was studied with Kaplan-Meier analysis.

RESULTS: Technically successful LA-ETVs were accomplished in 196 of the 202 patients (97%). The overall success rate for a functional LA-ETV was 68% at the 2-year follow-up evaluation. LA-ETV was more effective in patients aged 1 year and older (70% success rate) than in younger patients (59% success rate). Success rates were greater in patients with aqueductal stenosis or tumors as compared to other etiologies. Complications occurred in 22 procedures (10.3%). Only one patient (0.5%) experienced a major complication. No surgical mortalities or laser-related complications occurred.

CONCLUSION: This study demonstrates that LA-ETV is a safe and effective procedure that is comparable to other techniques for ETV. LA-ETV is most effective in patients aged 1 year and older and in patients with aqueductal stenosis and tumors, with a low major complication rate.

Original languageEnglish
Pages (from-to)437-43; discussion 443-4
JournalNeurosurgery
Volume62
Issue number2
DOIs
Publication statusPublished - Feb 2008

Cite this

van Beijnum, Janneke ; Hanlo, Patrick W ; Fischer, Kathelijn ; Majidpour, Mohsen M ; Kortekaas, Marlous F ; Verdaasdonk, Rudolf M ; Vandertop, W Peter. / Laser-assisted endoscopic third ventriculostomy : long-term results in a series of 202 patients. In: Neurosurgery. 2008 ; Vol. 62, No. 2. pp. 437-43; discussion 443-4.
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title = "Laser-assisted endoscopic third ventriculostomy: long-term results in a series of 202 patients",
abstract = "OBJECTIVE: Endoscopic third ventriculostomy is a well-known surgical option in the treatment of noncommunicating hydrocephalus. We studied complications and long-term success in 202 patients to demonstrate the safety and efficacy of laser-assisted endoscopic third ventriculostomy (LA-ETV) using a unique {"}black{"} fiber tip/diode laser combination for controlled tissue ablation.METHODS: We studied 213 LA-ETVs, which were performed in 202 patients. Patients' ages ranged from 2 days to 83 years (mean age, 27 yr). The mean follow-up period for all patients was 2.7 years (range, 2 d to 12 yr). Hydrocephalus was caused by aqueductal stenosis in 65 patients, tumors in 67 patients, hemorrhages in 24 patients, myelomeningoceles in 20 patients, cysts in 15 patients, and other causes in 11 patients. The long-term effectiveness of LA-ETV was studied with Kaplan-Meier analysis.RESULTS: Technically successful LA-ETVs were accomplished in 196 of the 202 patients (97{\%}). The overall success rate for a functional LA-ETV was 68{\%} at the 2-year follow-up evaluation. LA-ETV was more effective in patients aged 1 year and older (70{\%} success rate) than in younger patients (59{\%} success rate). Success rates were greater in patients with aqueductal stenosis or tumors as compared to other etiologies. Complications occurred in 22 procedures (10.3{\%}). Only one patient (0.5{\%}) experienced a major complication. No surgical mortalities or laser-related complications occurred.CONCLUSION: This study demonstrates that LA-ETV is a safe and effective procedure that is comparable to other techniques for ETV. LA-ETV is most effective in patients aged 1 year and older and in patients with aqueductal stenosis and tumors, with a low major complication rate.",
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Laser-assisted endoscopic third ventriculostomy : long-term results in a series of 202 patients. / van Beijnum, Janneke; Hanlo, Patrick W; Fischer, Kathelijn; Majidpour, Mohsen M; Kortekaas, Marlous F; Verdaasdonk, Rudolf M; Vandertop, W Peter.

In: Neurosurgery, Vol. 62, No. 2, 02.2008, p. 437-43; discussion 443-4.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Laser-assisted endoscopic third ventriculostomy

T2 - long-term results in a series of 202 patients

AU - van Beijnum, Janneke

AU - Hanlo, Patrick W

AU - Fischer, Kathelijn

AU - Majidpour, Mohsen M

AU - Kortekaas, Marlous F

AU - Verdaasdonk, Rudolf M

AU - Vandertop, W Peter

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N2 - OBJECTIVE: Endoscopic third ventriculostomy is a well-known surgical option in the treatment of noncommunicating hydrocephalus. We studied complications and long-term success in 202 patients to demonstrate the safety and efficacy of laser-assisted endoscopic third ventriculostomy (LA-ETV) using a unique "black" fiber tip/diode laser combination for controlled tissue ablation.METHODS: We studied 213 LA-ETVs, which were performed in 202 patients. Patients' ages ranged from 2 days to 83 years (mean age, 27 yr). The mean follow-up period for all patients was 2.7 years (range, 2 d to 12 yr). Hydrocephalus was caused by aqueductal stenosis in 65 patients, tumors in 67 patients, hemorrhages in 24 patients, myelomeningoceles in 20 patients, cysts in 15 patients, and other causes in 11 patients. The long-term effectiveness of LA-ETV was studied with Kaplan-Meier analysis.RESULTS: Technically successful LA-ETVs were accomplished in 196 of the 202 patients (97%). The overall success rate for a functional LA-ETV was 68% at the 2-year follow-up evaluation. LA-ETV was more effective in patients aged 1 year and older (70% success rate) than in younger patients (59% success rate). Success rates were greater in patients with aqueductal stenosis or tumors as compared to other etiologies. Complications occurred in 22 procedures (10.3%). Only one patient (0.5%) experienced a major complication. No surgical mortalities or laser-related complications occurred.CONCLUSION: This study demonstrates that LA-ETV is a safe and effective procedure that is comparable to other techniques for ETV. LA-ETV is most effective in patients aged 1 year and older and in patients with aqueductal stenosis and tumors, with a low major complication rate.

AB - OBJECTIVE: Endoscopic third ventriculostomy is a well-known surgical option in the treatment of noncommunicating hydrocephalus. We studied complications and long-term success in 202 patients to demonstrate the safety and efficacy of laser-assisted endoscopic third ventriculostomy (LA-ETV) using a unique "black" fiber tip/diode laser combination for controlled tissue ablation.METHODS: We studied 213 LA-ETVs, which were performed in 202 patients. Patients' ages ranged from 2 days to 83 years (mean age, 27 yr). The mean follow-up period for all patients was 2.7 years (range, 2 d to 12 yr). Hydrocephalus was caused by aqueductal stenosis in 65 patients, tumors in 67 patients, hemorrhages in 24 patients, myelomeningoceles in 20 patients, cysts in 15 patients, and other causes in 11 patients. The long-term effectiveness of LA-ETV was studied with Kaplan-Meier analysis.RESULTS: Technically successful LA-ETVs were accomplished in 196 of the 202 patients (97%). The overall success rate for a functional LA-ETV was 68% at the 2-year follow-up evaluation. LA-ETV was more effective in patients aged 1 year and older (70% success rate) than in younger patients (59% success rate). Success rates were greater in patients with aqueductal stenosis or tumors as compared to other etiologies. Complications occurred in 22 procedures (10.3%). Only one patient (0.5%) experienced a major complication. No surgical mortalities or laser-related complications occurred.CONCLUSION: This study demonstrates that LA-ETV is a safe and effective procedure that is comparable to other techniques for ETV. LA-ETV is most effective in patients aged 1 year and older and in patients with aqueductal stenosis and tumors, with a low major complication rate.

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KW - Middle Aged

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van Beijnum J, Hanlo PW, Fischer K, Majidpour MM, Kortekaas MF, Verdaasdonk RM et al. Laser-assisted endoscopic third ventriculostomy: long-term results in a series of 202 patients. Neurosurgery. 2008 Feb;62(2):437-43; discussion 443-4. https://doi.org/10.1227/01.neu.0000316011.13174.b1