Long non-coding RNA in vascular disease and aging

Diewertje I. Bink, Noelia Lozano-Vidal, Reinier A. Boon

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Cardiovascular diseases are the most prominent cause of death inWestern society, especially in the elderly. With the increasing life expectancy, the number of patients with cardiovascular diseases will rise in the near future, leading to an increased healthcare burden. There is a need for new therapies to treat this growing number of patients. The discovery of long non-coding RNAs has led to a novel group of molecules that could be considered for their potential as therapeutic targets. This review presents an overview of long non-coding RNAs that are regulated in vascular disease and aging and which might therefore give insight into new pathways that could be targeted to diagnose, prevent, and/or treat vascular diseases.
Original languageEnglish
Article number26
JournalNon-coding RNA
Volume5
Issue number1
DOIs
Publication statusPublished - 1 Jan 2019

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