Loss of CD47 Makes Dendritic Cells See Red

Timo K van den Berg; Robin van Bruggen

doi:10.1016/j.immuni.2015.09.008

Loss of CD47 Makes Dendritic Cells See Red

Timo K van den Berg, Robin van Bruggen

Molecular cell biology and Immunology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Whereas dendritic cells (DCs) can be activated in many ways to trigger immunity, hardly anything is known about the mechanisms that counterbalance DC activation. Cyster and colleagues now demonstrate that the "self" molecule CD47 on erythrocytes critically restricts splenic DC activation.

Original language	English
Pages (from-to)	622-4
Number of pages	3
Journal	Immunity
Volume	43
Issue number	4
DOIs	https://doi.org/10.1016/j.immuni.2015.09.008
Publication status	Published - 20 Oct 2015

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10.1016/j.immuni.2015.09.008

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van den Berg, T. K., & van Bruggen, R. (2015). Loss of CD47 Makes Dendritic Cells See Red. Immunity, 43(4), 622-4. https://doi.org/10.1016/j.immuni.2015.09.008

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title = "Loss of CD47 Makes Dendritic Cells See Red",

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KW - Dendritic Cells/immunology

KW - Erythrocytes/immunology

KW - Receptors, Immunologic/immunology

KW - Self Tolerance/immunology

KW - Spleen/immunology

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