Loss of CD47 Makes Dendritic Cells See Red

Timo K van den Berg, Robin van Bruggen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Whereas dendritic cells (DCs) can be activated in many ways to trigger immunity, hardly anything is known about the mechanisms that counterbalance DC activation. Cyster and colleagues now demonstrate that the "self" molecule CD47 on erythrocytes critically restricts splenic DC activation.

Original languageEnglish
Pages (from-to)622-4
Number of pages3
JournalImmunity
Volume43
Issue number4
DOIs
Publication statusPublished - 20 Oct 2015

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