Magnetic resonance imaging of myocardial infarction: Correlation with enzymatic, angiographic, and radionuclide findings

X. Hanno Krauss, Ernst E. van der Wall, Arnoud van der Laarse, Joost Doornbos, Niels A A Matheijssen, Albert de Roos, Jacobus A K Blokland, Ad E. van Voorthuisen, Albert V G Bruschke

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Spin-echo cardiac magnetic resonance imaging studies were performed in 20 patients with a first 7-to 14-day-old (mean 10) myocardial infarction. The magnetic resonance imaging findings were compared with coronary angiography (14 patients), myocardial enzyme release (18 patients), radionuclide angiography (19 patients), and thallium-201 perfusion scintigraphy (19 patients). Regional T2 relaxation times determined from the signal intensities at echo times 30 msec and 90 msec were significantly prolonged in the infarcted areas. Based on abnormal T2 times for every patient, a regional and a total myocardial damage score was determined. The infarct-related artery was correctly identified in 93% of patients by magnetic resonance imaging, in 79% of patients by thallium-201 scintigraphy, and in 62% of patients by radionuclide angiography. The total damage score correlated well with enzymatic infarct size (r = 0.75, p < 0.001). The correlation between left ventricular end-systolic volume index determined by magnetic resonance imaging and by radionuclide angiography was r = 0.89 (p < 0.002). The left ventricular end-systolic volume index correlated significantly with enzymatic infarct size (r = 0.72, p < 0.001), total damage score (r = 0.68, p < 0.002), and radionuclide left ventricular ejection fraction (r = -0.68, p < 0.002). Correlations between the magnetic resonance damage score and the thallium-201 perfusion score were r = 0.60 (p < 0.01) for the exercise images, and r = 0.72 (p < 0.001) for the redistribution images. This study shows that spin-echo magnetic resonance imaging is quite comparable with the established noninvasive imaging modalities currently used in patients with acute myocardial infarction.

Original languageEnglish
Pages (from-to)1274-1283
Number of pages10
JournalAmerican Heart Journal
Volume122
Issue number5
DOIs
Publication statusPublished - 1 Jan 1991

Cite this

Krauss, X. Hanno ; van der Wall, Ernst E. ; van der Laarse, Arnoud ; Doornbos, Joost ; Matheijssen, Niels A A ; de Roos, Albert ; Blokland, Jacobus A K ; van Voorthuisen, Ad E. ; Bruschke, Albert V G. / Magnetic resonance imaging of myocardial infarction : Correlation with enzymatic, angiographic, and radionuclide findings. In: American Heart Journal. 1991 ; Vol. 122, No. 5. pp. 1274-1283.
@article{158c6382e4914790959aa9f89ff05bff,
title = "Magnetic resonance imaging of myocardial infarction: Correlation with enzymatic, angiographic, and radionuclide findings",
abstract = "Spin-echo cardiac magnetic resonance imaging studies were performed in 20 patients with a first 7-to 14-day-old (mean 10) myocardial infarction. The magnetic resonance imaging findings were compared with coronary angiography (14 patients), myocardial enzyme release (18 patients), radionuclide angiography (19 patients), and thallium-201 perfusion scintigraphy (19 patients). Regional T2 relaxation times determined from the signal intensities at echo times 30 msec and 90 msec were significantly prolonged in the infarcted areas. Based on abnormal T2 times for every patient, a regional and a total myocardial damage score was determined. The infarct-related artery was correctly identified in 93{\%} of patients by magnetic resonance imaging, in 79{\%} of patients by thallium-201 scintigraphy, and in 62{\%} of patients by radionuclide angiography. The total damage score correlated well with enzymatic infarct size (r = 0.75, p < 0.001). The correlation between left ventricular end-systolic volume index determined by magnetic resonance imaging and by radionuclide angiography was r = 0.89 (p < 0.002). The left ventricular end-systolic volume index correlated significantly with enzymatic infarct size (r = 0.72, p < 0.001), total damage score (r = 0.68, p < 0.002), and radionuclide left ventricular ejection fraction (r = -0.68, p < 0.002). Correlations between the magnetic resonance damage score and the thallium-201 perfusion score were r = 0.60 (p < 0.01) for the exercise images, and r = 0.72 (p < 0.001) for the redistribution images. This study shows that spin-echo magnetic resonance imaging is quite comparable with the established noninvasive imaging modalities currently used in patients with acute myocardial infarction.",
author = "Krauss, {X. Hanno} and {van der Wall}, {Ernst E.} and {van der Laarse}, Arnoud and Joost Doornbos and Matheijssen, {Niels A A} and {de Roos}, Albert and Blokland, {Jacobus A K} and {van Voorthuisen}, {Ad E.} and Bruschke, {Albert V G}",
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Krauss, XH, van der Wall, EE, van der Laarse, A, Doornbos, J, Matheijssen, NAA, de Roos, A, Blokland, JAK, van Voorthuisen, AE & Bruschke, AVG 1991, 'Magnetic resonance imaging of myocardial infarction: Correlation with enzymatic, angiographic, and radionuclide findings' American Heart Journal, vol. 122, no. 5, pp. 1274-1283. https://doi.org/10.1016/0002-8703(91)90566-Z

Magnetic resonance imaging of myocardial infarction : Correlation with enzymatic, angiographic, and radionuclide findings. / Krauss, X. Hanno; van der Wall, Ernst E.; van der Laarse, Arnoud; Doornbos, Joost; Matheijssen, Niels A A; de Roos, Albert; Blokland, Jacobus A K; van Voorthuisen, Ad E.; Bruschke, Albert V G.

In: American Heart Journal, Vol. 122, No. 5, 01.01.1991, p. 1274-1283.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Krauss, X. Hanno

AU - van der Wall, Ernst E.

AU - van der Laarse, Arnoud

AU - Doornbos, Joost

AU - Matheijssen, Niels A A

AU - de Roos, Albert

AU - Blokland, Jacobus A K

AU - van Voorthuisen, Ad E.

AU - Bruschke, Albert V G

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