TY - JOUR
T1 - Magnetic resonance imaging of myocardial infarction
T2 - Correlation with enzymatic, angiographic, and radionuclide findings
AU - Krauss, X. Hanno
AU - van der Wall, Ernst E.
AU - van der Laarse, Arnoud
AU - Doornbos, Joost
AU - Matheijssen, Niels A A
AU - de Roos, Albert
AU - Blokland, Jacobus A K
AU - van Voorthuisen, Ad E.
AU - Bruschke, Albert V G
PY - 1991/1/1
Y1 - 1991/1/1
N2 - Spin-echo cardiac magnetic resonance imaging studies were performed in 20 patients with a first 7-to 14-day-old (mean 10) myocardial infarction. The magnetic resonance imaging findings were compared with coronary angiography (14 patients), myocardial enzyme release (18 patients), radionuclide angiography (19 patients), and thallium-201 perfusion scintigraphy (19 patients). Regional T2 relaxation times determined from the signal intensities at echo times 30 msec and 90 msec were significantly prolonged in the infarcted areas. Based on abnormal T2 times for every patient, a regional and a total myocardial damage score was determined. The infarct-related artery was correctly identified in 93% of patients by magnetic resonance imaging, in 79% of patients by thallium-201 scintigraphy, and in 62% of patients by radionuclide angiography. The total damage score correlated well with enzymatic infarct size (r = 0.75, p < 0.001). The correlation between left ventricular end-systolic volume index determined by magnetic resonance imaging and by radionuclide angiography was r = 0.89 (p < 0.002). The left ventricular end-systolic volume index correlated significantly with enzymatic infarct size (r = 0.72, p < 0.001), total damage score (r = 0.68, p < 0.002), and radionuclide left ventricular ejection fraction (r = -0.68, p < 0.002). Correlations between the magnetic resonance damage score and the thallium-201 perfusion score were r = 0.60 (p < 0.01) for the exercise images, and r = 0.72 (p < 0.001) for the redistribution images. This study shows that spin-echo magnetic resonance imaging is quite comparable with the established noninvasive imaging modalities currently used in patients with acute myocardial infarction.
AB - Spin-echo cardiac magnetic resonance imaging studies were performed in 20 patients with a first 7-to 14-day-old (mean 10) myocardial infarction. The magnetic resonance imaging findings were compared with coronary angiography (14 patients), myocardial enzyme release (18 patients), radionuclide angiography (19 patients), and thallium-201 perfusion scintigraphy (19 patients). Regional T2 relaxation times determined from the signal intensities at echo times 30 msec and 90 msec were significantly prolonged in the infarcted areas. Based on abnormal T2 times for every patient, a regional and a total myocardial damage score was determined. The infarct-related artery was correctly identified in 93% of patients by magnetic resonance imaging, in 79% of patients by thallium-201 scintigraphy, and in 62% of patients by radionuclide angiography. The total damage score correlated well with enzymatic infarct size (r = 0.75, p < 0.001). The correlation between left ventricular end-systolic volume index determined by magnetic resonance imaging and by radionuclide angiography was r = 0.89 (p < 0.002). The left ventricular end-systolic volume index correlated significantly with enzymatic infarct size (r = 0.72, p < 0.001), total damage score (r = 0.68, p < 0.002), and radionuclide left ventricular ejection fraction (r = -0.68, p < 0.002). Correlations between the magnetic resonance damage score and the thallium-201 perfusion score were r = 0.60 (p < 0.01) for the exercise images, and r = 0.72 (p < 0.001) for the redistribution images. This study shows that spin-echo magnetic resonance imaging is quite comparable with the established noninvasive imaging modalities currently used in patients with acute myocardial infarction.
UR - http://www.scopus.com/inward/record.url?scp=0025993004&partnerID=8YFLogxK
U2 - 10.1016/0002-8703(91)90566-Z
DO - 10.1016/0002-8703(91)90566-Z
M3 - Article
C2 - 1950989
AN - SCOPUS:0025993004
VL - 122
SP - 1274
EP - 1283
JO - American Heart Journal
JF - American Heart Journal
SN - 1097-6744
IS - 5
ER -