Magnetic resonance imaging of the lumbosacral spine in children with chronic constipation or non-retentive fecal incontinence: a prospective study

Noor-L-Houda Bekkali, Eveline E O Hagebeuk, Marloes E J Bongers, Rick R van Rijn, Michiel P Van Wijk, Olivia Liem, Marc A Benninga

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: To determine the prevalence of lumbosacral spine (LSS) abnormalities in children with defecation disorders, intractable constipation, or non-retentive fecal incontinence (NRFI) and evaluate whether LSS abnormalities on magnetic resonance imaging (MRI) are clinically detected by neurologic examination.

STUDY DESIGN: MRI of the LSS and complete neurologic examination by a pediatric neurologist blinded to the MRI results were performed in patients with intractable defecation disorders.

RESULTS: Patients with intractable constipation (n = 130; 76 males; median age, 11 years; range, 6-18 years), and patients with NRFI (n = 28; 18 males; median age, 10 years; range, 7-15 years) participated. One occult spina bifida (OSB) and 3 terminal filum lipomas were found in patients with a normal neurologic examination. One patient had a terminal filum lipoma and neurologic complaints. Gluteal cleft deviation was found in 3 of 4 patients with LSS abnormalities. Neurosurgical treatment was not required in any patient during the 12-week follow-up.

CONCLUSIONS: MRI showed LSS abnormalities in 3% of patients with defecation disorders and normal neurologic examination, all of whom reported symptom relief at the 12-week follow-up without neurosurgical intervention. Thus, whether or not LSS abnormalities play a role in defecation disorders remains unclear.

Original languageEnglish
Pages (from-to)461-5
Number of pages5
JournalJournal of Pediatrics
Volume156
Issue number3
DOIs
Publication statusPublished - Mar 2010

Cite this

Bekkali, Noor-L-Houda ; Hagebeuk, Eveline E O ; Bongers, Marloes E J ; van Rijn, Rick R ; Van Wijk, Michiel P ; Liem, Olivia ; Benninga, Marc A. / Magnetic resonance imaging of the lumbosacral spine in children with chronic constipation or non-retentive fecal incontinence : a prospective study. In: Journal of Pediatrics. 2010 ; Vol. 156, No. 3. pp. 461-5.
@article{651910c718d64663929d52c656d69896,
title = "Magnetic resonance imaging of the lumbosacral spine in children with chronic constipation or non-retentive fecal incontinence: a prospective study",
abstract = "OBJECTIVE: To determine the prevalence of lumbosacral spine (LSS) abnormalities in children with defecation disorders, intractable constipation, or non-retentive fecal incontinence (NRFI) and evaluate whether LSS abnormalities on magnetic resonance imaging (MRI) are clinically detected by neurologic examination.STUDY DESIGN: MRI of the LSS and complete neurologic examination by a pediatric neurologist blinded to the MRI results were performed in patients with intractable defecation disorders.RESULTS: Patients with intractable constipation (n = 130; 76 males; median age, 11 years; range, 6-18 years), and patients with NRFI (n = 28; 18 males; median age, 10 years; range, 7-15 years) participated. One occult spina bifida (OSB) and 3 terminal filum lipomas were found in patients with a normal neurologic examination. One patient had a terminal filum lipoma and neurologic complaints. Gluteal cleft deviation was found in 3 of 4 patients with LSS abnormalities. Neurosurgical treatment was not required in any patient during the 12-week follow-up.CONCLUSIONS: MRI showed LSS abnormalities in 3{\%} of patients with defecation disorders and normal neurologic examination, all of whom reported symptom relief at the 12-week follow-up without neurosurgical intervention. Thus, whether or not LSS abnormalities play a role in defecation disorders remains unclear.",
keywords = "Adolescent, Cauda Equina, Child, Chronic Disease, Constipation/etiology, Fecal Incontinence/etiology, Female, Humans, Lipoma/complications, Lumbar Vertebrae/pathology, Magnetic Resonance Imaging, Male, Neural Tube Defects/complications, Sacrum/pathology, Spinal Dysraphism/complications, Spinal Neoplasms/diagnosis",
author = "Noor-L-Houda Bekkali and Hagebeuk, {Eveline E O} and Bongers, {Marloes E J} and {van Rijn}, {Rick R} and {Van Wijk}, {Michiel P} and Olivia Liem and Benninga, {Marc A}",
note = "Copyright 2010 Mosby, Inc. All rights reserved.",
year = "2010",
month = "3",
doi = "10.1016/j.jpeds.2009.09.048",
language = "English",
volume = "156",
pages = "461--5",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "3",

}

Magnetic resonance imaging of the lumbosacral spine in children with chronic constipation or non-retentive fecal incontinence : a prospective study. / Bekkali, Noor-L-Houda; Hagebeuk, Eveline E O; Bongers, Marloes E J; van Rijn, Rick R; Van Wijk, Michiel P; Liem, Olivia; Benninga, Marc A.

In: Journal of Pediatrics, Vol. 156, No. 3, 03.2010, p. 461-5.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Magnetic resonance imaging of the lumbosacral spine in children with chronic constipation or non-retentive fecal incontinence

T2 - a prospective study

AU - Bekkali, Noor-L-Houda

AU - Hagebeuk, Eveline E O

AU - Bongers, Marloes E J

AU - van Rijn, Rick R

AU - Van Wijk, Michiel P

AU - Liem, Olivia

AU - Benninga, Marc A

N1 - Copyright 2010 Mosby, Inc. All rights reserved.

PY - 2010/3

Y1 - 2010/3

N2 - OBJECTIVE: To determine the prevalence of lumbosacral spine (LSS) abnormalities in children with defecation disorders, intractable constipation, or non-retentive fecal incontinence (NRFI) and evaluate whether LSS abnormalities on magnetic resonance imaging (MRI) are clinically detected by neurologic examination.STUDY DESIGN: MRI of the LSS and complete neurologic examination by a pediatric neurologist blinded to the MRI results were performed in patients with intractable defecation disorders.RESULTS: Patients with intractable constipation (n = 130; 76 males; median age, 11 years; range, 6-18 years), and patients with NRFI (n = 28; 18 males; median age, 10 years; range, 7-15 years) participated. One occult spina bifida (OSB) and 3 terminal filum lipomas were found in patients with a normal neurologic examination. One patient had a terminal filum lipoma and neurologic complaints. Gluteal cleft deviation was found in 3 of 4 patients with LSS abnormalities. Neurosurgical treatment was not required in any patient during the 12-week follow-up.CONCLUSIONS: MRI showed LSS abnormalities in 3% of patients with defecation disorders and normal neurologic examination, all of whom reported symptom relief at the 12-week follow-up without neurosurgical intervention. Thus, whether or not LSS abnormalities play a role in defecation disorders remains unclear.

AB - OBJECTIVE: To determine the prevalence of lumbosacral spine (LSS) abnormalities in children with defecation disorders, intractable constipation, or non-retentive fecal incontinence (NRFI) and evaluate whether LSS abnormalities on magnetic resonance imaging (MRI) are clinically detected by neurologic examination.STUDY DESIGN: MRI of the LSS and complete neurologic examination by a pediatric neurologist blinded to the MRI results were performed in patients with intractable defecation disorders.RESULTS: Patients with intractable constipation (n = 130; 76 males; median age, 11 years; range, 6-18 years), and patients with NRFI (n = 28; 18 males; median age, 10 years; range, 7-15 years) participated. One occult spina bifida (OSB) and 3 terminal filum lipomas were found in patients with a normal neurologic examination. One patient had a terminal filum lipoma and neurologic complaints. Gluteal cleft deviation was found in 3 of 4 patients with LSS abnormalities. Neurosurgical treatment was not required in any patient during the 12-week follow-up.CONCLUSIONS: MRI showed LSS abnormalities in 3% of patients with defecation disorders and normal neurologic examination, all of whom reported symptom relief at the 12-week follow-up without neurosurgical intervention. Thus, whether or not LSS abnormalities play a role in defecation disorders remains unclear.

KW - Adolescent

KW - Cauda Equina

KW - Child

KW - Chronic Disease

KW - Constipation/etiology

KW - Fecal Incontinence/etiology

KW - Female

KW - Humans

KW - Lipoma/complications

KW - Lumbar Vertebrae/pathology

KW - Magnetic Resonance Imaging

KW - Male

KW - Neural Tube Defects/complications

KW - Sacrum/pathology

KW - Spinal Dysraphism/complications

KW - Spinal Neoplasms/diagnosis

U2 - 10.1016/j.jpeds.2009.09.048

DO - 10.1016/j.jpeds.2009.09.048

M3 - Article

VL - 156

SP - 461

EP - 465

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 3

ER -