Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients

M. Weijers, G.B. Snow, P.D. Bezemer, I. van der Waal

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

There is an ongoing debate about the predictive value of histopathological parameters in oral cancer. In the past decades, the emphasis was on the possible added value of the so-called malignancy grading system. In a retrospective study on 128 previously untreated patients with a T1 or T2 squamous cell carcinoma of the tongue and the floor of the mouth, the value of the classical Broders' grading system and the malignancy grading system were compared with regard to various outcome measures such as regional metastasis, local recurrence and 5-year survival. The results show that neither of the histological grading systems has a strong predictive value and that none is superior to the other
Original languageUndefined/Unknown
Pages (from-to)343-347
JournalJournal of Oral Pathology and Medicine
Volume38
Issue number4
DOIs
Publication statusPublished - 2009

Cite this

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title = "Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients",
abstract = "There is an ongoing debate about the predictive value of histopathological parameters in oral cancer. In the past decades, the emphasis was on the possible added value of the so-called malignancy grading system. In a retrospective study on 128 previously untreated patients with a T1 or T2 squamous cell carcinoma of the tongue and the floor of the mouth, the value of the classical Broders' grading system and the malignancy grading system were compared with regard to various outcome measures such as regional metastasis, local recurrence and 5-year survival. The results show that neither of the histological grading systems has a strong predictive value and that none is superior to the other",
author = "M. Weijers and G.B. Snow and P.D. Bezemer and {van der Waal}, I.",
year = "2009",
doi = "10.1111/j.1600-0714.2009.00751.x",
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Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients. / Weijers, M.; Snow, G.B.; Bezemer, P.D.; van der Waal, I.

In: Journal of Oral Pathology and Medicine, Vol. 38, No. 4, 2009, p. 343-347.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Malignancy grading is no better than conventional histopathological grading in small squamous cell carcinoma of tongue and floor of mouth: retrospective study in 128 patients

AU - Weijers, M.

AU - Snow, G.B.

AU - Bezemer, P.D.

AU - van der Waal, I.

PY - 2009

Y1 - 2009

N2 - There is an ongoing debate about the predictive value of histopathological parameters in oral cancer. In the past decades, the emphasis was on the possible added value of the so-called malignancy grading system. In a retrospective study on 128 previously untreated patients with a T1 or T2 squamous cell carcinoma of the tongue and the floor of the mouth, the value of the classical Broders' grading system and the malignancy grading system were compared with regard to various outcome measures such as regional metastasis, local recurrence and 5-year survival. The results show that neither of the histological grading systems has a strong predictive value and that none is superior to the other

AB - There is an ongoing debate about the predictive value of histopathological parameters in oral cancer. In the past decades, the emphasis was on the possible added value of the so-called malignancy grading system. In a retrospective study on 128 previously untreated patients with a T1 or T2 squamous cell carcinoma of the tongue and the floor of the mouth, the value of the classical Broders' grading system and the malignancy grading system were compared with regard to various outcome measures such as regional metastasis, local recurrence and 5-year survival. The results show that neither of the histological grading systems has a strong predictive value and that none is superior to the other

U2 - 10.1111/j.1600-0714.2009.00751.x

DO - 10.1111/j.1600-0714.2009.00751.x

M3 - Article

VL - 38

SP - 343

EP - 347

JO - Journal of Oral Pathology and Medicine

JF - Journal of Oral Pathology and Medicine

SN - 0904-2512

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