Management of Multiple Secreting Paragangliomas in a Succinate Dehydrogenase Subunit D (SDHD) Variant Carrier

Johannes Rijken, Berry de Vos, René Leemans, Ben Zwezerijnen, Pim de Graaf, Erik Hensen, Koen Dreijerink, Chris Dickhoff, Petr Symersky

Research output: Contribution to journalArticleAcademicpeer-review


Management of functional intrathoracic sympathetic paragangliomas in succinate dehydrogenase subunit D (SDHD) mutation carriers is challenging, and there is no uniform guideline for treatment to date. The risks of potential malignant behavior and long-term cardiovascular morbidity have to be weighed against the risks of treatment complications. We report the multidisciplinary and shared decision-making approach that resulted in successful surgical removal of 3 paragangliomas in a SDHD mutation carrier.

Original languageEnglish
Pages (from-to)e87-e90
JournalThe Annals of Thoracic Surgery
Issue number2
Publication statusPublished - 1 Feb 2020

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