Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative

Yael A. Leshem*, Joanne R. Chalmers, Christian Apfelbacher, Masutaka Furue, Louise A.A. Gerbens, Cecilia A.C. Prinsen, Jochen Schmitt, Phyllis I. Spuls, Kim S. Thomas, Hywel C. Williams, Eric L. Simpson, Harmonising Outcome Measures for Eczema (HOME) initiative

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Background: Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema patients in routine clinical care. Objectives: Prioritize outcome domains to measure atopic eczema in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain. Methods: An online survey of HOME members identified and ranked 21 possible health domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality. Results: Patient-reported symptoms was the top-prioritized domain. In accordance with psychometric properties and feasibility, there was consensus that the recommended instruments to measure atopic eczema symptoms in clinical practice are the POEM, the PO-SCORAD index, or both. The numeric rating scale for itch received support pending definition and validation in atopic eczema. Conclusion: Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD index, or both for measuring atopic eczema symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.

Original languageEnglish
Pages (from-to)1181-1186
Number of pages6
JournalJournal of the American Academy of Dermatology
Issue number5
Publication statusPublished - May 2020

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