Medicamenteuze pijn- en symptoombestrijding bij het staken van de behandeling bij pasgeborenen en kinderen

Translated title of the contribution: Medicinal management of pain and symptoms following the withdraw al of treatment in babies and children

M. A.H.B.M. Van Der Hoeven, A. J.T. Reijntjens, G. M.W.R. De Wert, D. A. Van Waardenburg, L. J.I. Zimmermann, G. A.M. Widdershoven

Research output: Contribution to journalReview articleAcademicpeer-review


We present three cases to illus trate the end-of-life care after withdrawal of mechanical ventilation. In a one-year-old girl with meningococcal septic shock, muscle relaxants were continued when mechanical ventilation was withdrawn. In a 10-day-old girl with perinatal asphyxia a high dose of fentanyl was given before mechanical ventilation was withdrawn. A 6-week-old girl in a vegetative state was fighting for breath after detubation. At the request of the parents to end this condition, vecuronium bromide was given. In these three cases death was probably brought forward by a maximum of 12-24 hours. Three arguments can be presented to justify this: the relief of suffering, the perceptions of the parents and the fact that death was expected within a very short time. The administration of these medicines cannot, however, be considered normal medical practice. Therefore we argue that these cases should be reviewed by the national expert review committee and guidelines should be developed for appropriate palliative care after the withdrawal of mechanical ventilation.

Translated title of the contributionMedicinal management of pain and symptoms following the withdraw al of treatment in babies and children
Original languageDutch
Pages (from-to)2049-2052
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number38
Publication statusPublished - 20 Sep 2008

Cite this