Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

I.M. Heid, A.U. Jackson, J.C. Randall, T.W. Winkler, L. Qi, V. Steinthorsdottir, G. Thorleifsson, M.C. Zillikens, E.K. Speliotes, R. Mägi, T. Workalemahu, C.C. White, N. Bouatia-Naji, T.B. Harris, S.I. Berndt, E. Ingelsson, C.J. Willer, M.N. Weedon, J. Luan, S. Vedantam & 81 others T. Esko, T.O. Kilpeläinen, Z. Kutalik, S. Li, K.L. Monda, A.L. Dixon, C.C. Holmes, L.M. Kaplan, L. Liang, J.L. Min, M.F. Moffatt, C. Molony, G. Nicholson, E.E. Schadt, K.T. Zondervan, M.F. Feitosa, T. Ferreira, H. Lango Allen, R.J. Weyant, E. Wheeler, A.R. Wood, K. Estrada, M.E. Goddard, G. Lettre, M. Mangino, DR Nyholt, S. Purcell, A.V. Smith, H.M. Visscher, J. Yang, S.A. McCarroll, J. Nemesh, B.F. Voight, D. Absher, N. Amin, T. Aspelund, L. Coin, N.L. Glazer, C. Hayward, N.L. Heard-Costa, J.J. Hottenga, A. Johansson, T. Johnson, M. Kaakinen, K. Kapur, S. Ketkar, J.W. Knowles, P. Kraft, A.T. Kraja, C. Lamina, M.F. Leitzmann, B. McKnight, A.P. Morris, K.K. Ong, J.R.B. Perry, M.J. Peters, O. Polasek, I. Prokopenko, N.W. Rayner, S. Ripatti, F. Rivadeneira, R. Robertson, S. Sanna, U. Sovio, I. Surakka, A. Teumer, K.M.C. van Wingerden, V. Vitart, J.H. Zhao, C. Cavalcanti-Proença, P.S. Chines, E. Fisher, J.R. Kulzer, C. Lecoeur, N. Narisu, C. Sandholt, E.J.C. de Geus, G. Willemsen, B.W.J.H. Penninx, K.L. Mohlke, C.M. Lindgren

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)949-960
JournalNature Genetics
Volume42
Issue number11
DOIs
Publication statusPublished - 2010

Cite this

Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., ... Lindgren, C. M. (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics, 42(11), 949-960. https://doi.org/10.1038/ng.685
Heid, I.M. ; Jackson, A.U. ; Randall, J.C. ; Winkler, T.W. ; Qi, L. ; Steinthorsdottir, V. ; Thorleifsson, G. ; Zillikens, M.C. ; Speliotes, E.K. ; Mägi, R. ; Workalemahu, T. ; White, C.C. ; Bouatia-Naji, N. ; Harris, T.B. ; Berndt, S.I. ; Ingelsson, E. ; Willer, C.J. ; Weedon, M.N. ; Luan, J. ; Vedantam, S. ; Esko, T. ; Kilpeläinen, T.O. ; Kutalik, Z. ; Li, S. ; Monda, K.L. ; Dixon, A.L. ; Holmes, C.C. ; Kaplan, L.M. ; Liang, L. ; Min, J.L. ; Moffatt, M.F. ; Molony, C. ; Nicholson, G. ; Schadt, E.E. ; Zondervan, K.T. ; Feitosa, M.F. ; Ferreira, T. ; Lango Allen, H. ; Weyant, R.J. ; Wheeler, E. ; Wood, A.R. ; Estrada, K. ; Goddard, M.E. ; Lettre, G. ; Mangino, M. ; Nyholt, DR ; Purcell, S. ; Smith, A.V. ; Visscher, H.M. ; Yang, J. ; McCarroll, S.A. ; Nemesh, J. ; Voight, B.F. ; Absher, D. ; Amin, N. ; Aspelund, T. ; Coin, L. ; Glazer, N.L. ; Hayward, C. ; Heard-Costa, N.L. ; Hottenga, J.J. ; Johansson, A. ; Johnson, T. ; Kaakinen, M. ; Kapur, K. ; Ketkar, S. ; Knowles, J.W. ; Kraft, P. ; Kraja, A.T. ; Lamina, C. ; Leitzmann, M.F. ; McKnight, B. ; Morris, A.P. ; Ong, K.K. ; Perry, J.R.B. ; Peters, M.J. ; Polasek, O. ; Prokopenko, I. ; Rayner, N.W. ; Ripatti, S. ; Rivadeneira, F. ; Robertson, R. ; Sanna, S. ; Sovio, U. ; Surakka, I. ; Teumer, A. ; van Wingerden, K.M.C. ; Vitart, V. ; Zhao, J.H. ; Cavalcanti-Proença, C. ; Chines, P.S. ; Fisher, E. ; Kulzer, J.R. ; Lecoeur, C. ; Narisu, N. ; Sandholt, C. ; de Geus, E.J.C. ; Willemsen, G. ; Penninx, B.W.J.H. ; Mohlke, K.L. ; Lindgren, C.M. / Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. In: Nature Genetics. 2010 ; Vol. 42, No. 11. pp. 949-960.
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author = "I.M. Heid and A.U. Jackson and J.C. Randall and T.W. Winkler and L. Qi and V. Steinthorsdottir and G. Thorleifsson and M.C. Zillikens and E.K. Speliotes and R. M{\"a}gi and T. Workalemahu and C.C. White and N. Bouatia-Naji and T.B. Harris and S.I. Berndt and E. Ingelsson and C.J. Willer and M.N. Weedon and J. Luan and S. Vedantam and T. Esko and T.O. Kilpel{\"a}inen and Z. Kutalik and S. Li and K.L. Monda and A.L. Dixon and C.C. Holmes and L.M. Kaplan and L. Liang and J.L. Min and M.F. Moffatt and C. Molony and G. Nicholson and E.E. Schadt and K.T. Zondervan and M.F. Feitosa and T. Ferreira and {Lango Allen}, H. and R.J. Weyant and E. Wheeler and A.R. Wood and K. Estrada and M.E. Goddard and G. Lettre and M. Mangino and DR Nyholt and S. Purcell and A.V. Smith and H.M. Visscher and J. Yang and S.A. McCarroll and J. Nemesh and B.F. Voight and D. Absher and N. Amin and T. Aspelund and L. Coin and N.L. Glazer and C. Hayward and N.L. Heard-Costa and J.J. Hottenga and A. Johansson and T. Johnson and M. Kaakinen and K. Kapur and S. Ketkar and J.W. Knowles and P. Kraft and A.T. Kraja and C. Lamina and M.F. Leitzmann and B. McKnight and A.P. Morris and K.K. Ong and J.R.B. Perry and M.J. Peters and O. Polasek and I. Prokopenko and N.W. Rayner and S. Ripatti and F. Rivadeneira and R. Robertson and S. Sanna and U. Sovio and I. Surakka and A. Teumer and {van Wingerden}, K.M.C. and V. Vitart and J.H. Zhao and C. Cavalcanti-Proen{\cc}a and P.S. Chines and E. Fisher and J.R. Kulzer and C. Lecoeur and N. Narisu and C. Sandholt and {de Geus}, E.J.C. and G. Willemsen and B.W.J.H. Penninx and K.L. Mohlke and C.M. Lindgren",
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Heid, IM, Jackson, AU, Randall, JC, Winkler, TW, Qi, L, Steinthorsdottir, V, Thorleifsson, G, Zillikens, MC, Speliotes, EK, Mägi, R, Workalemahu, T, White, CC, Bouatia-Naji, N, Harris, TB, Berndt, SI, Ingelsson, E, Willer, CJ, Weedon, MN, Luan, J, Vedantam, S, Esko, T, Kilpeläinen, TO, Kutalik, Z, Li, S, Monda, KL, Dixon, AL, Holmes, CC, Kaplan, LM, Liang, L, Min, JL, Moffatt, MF, Molony, C, Nicholson, G, Schadt, EE, Zondervan, KT, Feitosa, MF, Ferreira, T, Lango Allen, H, Weyant, RJ, Wheeler, E, Wood, AR, Estrada, K, Goddard, ME, Lettre, G, Mangino, M, Nyholt, DR, Purcell, S, Smith, AV, Visscher, HM, Yang, J, McCarroll, SA, Nemesh, J, Voight, BF, Absher, D, Amin, N, Aspelund, T, Coin, L, Glazer, NL, Hayward, C, Heard-Costa, NL, Hottenga, JJ, Johansson, A, Johnson, T, Kaakinen, M, Kapur, K, Ketkar, S, Knowles, JW, Kraft, P, Kraja, AT, Lamina, C, Leitzmann, MF, McKnight, B, Morris, AP, Ong, KK, Perry, JRB, Peters, MJ, Polasek, O, Prokopenko, I, Rayner, NW, Ripatti, S, Rivadeneira, F, Robertson, R, Sanna, S, Sovio, U, Surakka, I, Teumer, A, van Wingerden, KMC, Vitart, V, Zhao, JH, Cavalcanti-Proença, C, Chines, PS, Fisher, E, Kulzer, JR, Lecoeur, C, Narisu, N, Sandholt, C, de Geus, EJC, Willemsen, G, Penninx, BWJH, Mohlke, KL & Lindgren, CM 2010, 'Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution' Nature Genetics, vol. 42, no. 11, pp. 949-960. https://doi.org/10.1038/ng.685

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. / Heid, I.M.; Jackson, A.U.; Randall, J.C.; Winkler, T.W.; Qi, L.; Steinthorsdottir, V.; Thorleifsson, G.; Zillikens, M.C.; Speliotes, E.K.; Mägi, R.; Workalemahu, T.; White, C.C.; Bouatia-Naji, N.; Harris, T.B.; Berndt, S.I.; Ingelsson, E.; Willer, C.J.; Weedon, M.N.; Luan, J.; Vedantam, S.; Esko, T.; Kilpeläinen, T.O.; Kutalik, Z.; Li, S.; Monda, K.L.; Dixon, A.L.; Holmes, C.C.; Kaplan, L.M.; Liang, L.; Min, J.L.; Moffatt, M.F.; Molony, C.; Nicholson, G.; Schadt, E.E.; Zondervan, K.T.; Feitosa, M.F.; Ferreira, T.; Lango Allen, H.; Weyant, R.J.; Wheeler, E.; Wood, A.R.; Estrada, K.; Goddard, M.E.; Lettre, G.; Mangino, M.; Nyholt, DR; Purcell, S.; Smith, A.V.; Visscher, H.M.; Yang, J.; McCarroll, S.A.; Nemesh, J.; Voight, B.F.; Absher, D.; Amin, N.; Aspelund, T.; Coin, L.; Glazer, N.L.; Hayward, C.; Heard-Costa, N.L.; Hottenga, J.J.; Johansson, A.; Johnson, T.; Kaakinen, M.; Kapur, K.; Ketkar, S.; Knowles, J.W.; Kraft, P.; Kraja, A.T.; Lamina, C.; Leitzmann, M.F.; McKnight, B.; Morris, A.P.; Ong, K.K.; Perry, J.R.B.; Peters, M.J.; Polasek, O.; Prokopenko, I.; Rayner, N.W.; Ripatti, S.; Rivadeneira, F.; Robertson, R.; Sanna, S.; Sovio, U.; Surakka, I.; Teumer, A.; van Wingerden, K.M.C.; Vitart, V.; Zhao, J.H.; Cavalcanti-Proença, C.; Chines, P.S.; Fisher, E.; Kulzer, J.R.; Lecoeur, C.; Narisu, N.; Sandholt, C.; de Geus, E.J.C.; Willemsen, G.; Penninx, B.W.J.H.; Mohlke, K.L.; Lindgren, C.M.

In: Nature Genetics, Vol. 42, No. 11, 2010, p. 949-960.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

AU - Heid, I.M.

AU - Jackson, A.U.

AU - Randall, J.C.

AU - Winkler, T.W.

AU - Qi, L.

AU - Steinthorsdottir, V.

AU - Thorleifsson, G.

AU - Zillikens, M.C.

AU - Speliotes, E.K.

AU - Mägi, R.

AU - Workalemahu, T.

AU - White, C.C.

AU - Bouatia-Naji, N.

AU - Harris, T.B.

AU - Berndt, S.I.

AU - Ingelsson, E.

AU - Willer, C.J.

AU - Weedon, M.N.

AU - Luan, J.

AU - Vedantam, S.

AU - Esko, T.

AU - Kilpeläinen, T.O.

AU - Kutalik, Z.

AU - Li, S.

AU - Monda, K.L.

AU - Dixon, A.L.

AU - Holmes, C.C.

AU - Kaplan, L.M.

AU - Liang, L.

AU - Min, J.L.

AU - Moffatt, M.F.

AU - Molony, C.

AU - Nicholson, G.

AU - Schadt, E.E.

AU - Zondervan, K.T.

AU - Feitosa, M.F.

AU - Ferreira, T.

AU - Lango Allen, H.

AU - Weyant, R.J.

AU - Wheeler, E.

AU - Wood, A.R.

AU - Estrada, K.

AU - Goddard, M.E.

AU - Lettre, G.

AU - Mangino, M.

AU - Nyholt, DR

AU - Purcell, S.

AU - Smith, A.V.

AU - Visscher, H.M.

AU - Yang, J.

AU - McCarroll, S.A.

AU - Nemesh, J.

AU - Voight, B.F.

AU - Absher, D.

AU - Amin, N.

AU - Aspelund, T.

AU - Coin, L.

AU - Glazer, N.L.

AU - Hayward, C.

AU - Heard-Costa, N.L.

AU - Hottenga, J.J.

AU - Johansson, A.

AU - Johnson, T.

AU - Kaakinen, M.

AU - Kapur, K.

AU - Ketkar, S.

AU - Knowles, J.W.

AU - Kraft, P.

AU - Kraja, A.T.

AU - Lamina, C.

AU - Leitzmann, M.F.

AU - McKnight, B.

AU - Morris, A.P.

AU - Ong, K.K.

AU - Perry, J.R.B.

AU - Peters, M.J.

AU - Polasek, O.

AU - Prokopenko, I.

AU - Rayner, N.W.

AU - Ripatti, S.

AU - Rivadeneira, F.

AU - Robertson, R.

AU - Sanna, S.

AU - Sovio, U.

AU - Surakka, I.

AU - Teumer, A.

AU - van Wingerden, K.M.C.

AU - Vitart, V.

AU - Zhao, J.H.

AU - Cavalcanti-Proença, C.

AU - Chines, P.S.

AU - Fisher, E.

AU - Kulzer, J.R.

AU - Lecoeur, C.

AU - Narisu, N.

AU - Sandholt, C.

AU - de Geus, E.J.C.

AU - Willemsen, G.

AU - Penninx, B.W.J.H.

AU - Mohlke, K.L.

AU - Lindgren, C.M.

PY - 2010

Y1 - 2010

U2 - 10.1038/ng.685

DO - 10.1038/ng.685

M3 - Article

VL - 42

SP - 949

EP - 960

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 11

ER -