Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

M.H.M. de Moor; S.M. van den Berg; C.J.H. Verweij; R.F. Krueger; M. Luciano; A. Arias-Vasquez; L.K. Matteson; J. Derringer; T. Esko; N. Amin; S.D. Gordon; N.K. Hansell; A.B. Hart; I. Seppälä; J.E. Huffman; B. Konte; J. Lahti; M.Y. Lee; M. Miller; T. Nutile; T. Tanaka; A. Teumer; A. Viktorin; J. Wedenoja; G.R. Abecasis; D.E. Adkins; A. Agrawal; J. Allik; K. Appel; T.B. Bigdeli; F. Busonero; H. Campbell; P.T. Costa; G. Davey Smith; G. Davies; H. de Wit; J. Ding; B.E. Engelhardt; J.G. Eriksson; I.O. Fedko; L. Ferrucci; B. Franke; I. Giegling; R. Grucza; A.M. Hartmann; A.C. Heath; K. Heinonen; A.K. Henders; G. Homuth; J.J. Hottenga; W.G. Iacono; J. Janzing; M Jokela; R. Karlsson; J.P. Kemp; M.G. Kirkpatrick; A. Latvala; T. Lehtimäki; D.C. Liewald; P.A.F. Madden; C. Magri; P.K.E. Magnusson; J. Marten; A. Maschio; S.E. Medland; E. Mihailov; Y. Milaneschi; G.W. Montgomery; M. Nauck; K.G. Ouwens; A. Palotie; E. Pettersson; O. Polasek; Y. Qian; L. Pulkki-Råback; O.T. Raitakari; A. Realo; R.J. Rose; D. Ruggiero; C.O. Schmidt; W.S. Slutske; R. Sorice; J.M. Starr; B. St Pourcain; A.R. Sutin; N.J. Timpson; H. Trochet; S. Vermeulen; E. Vuoksimaa; E. Widén; J. Wouda; M.J. Wright; L. Zgaga; D. Porteous; A. Minelli; A.A. Palmer; D. Rujescu; M. Ciullo; C. Hayward; I. Rudan; A. Metspalu; J. Kaprio; I.J. Deary; K. Räikkönen; J.F. Wilson; L. Keltikangas-Järvinen; L.J. Bierut; J.M. Hettema; H.J. Grabe; C.M. van Duijn; D.M. Evans; D. Schlessinger; N.L. Pedersen; A. Terracciano; M. McGue; B.W.J.H. Penninx; N.G. Martin; D.I. Boomsma

doi:10.1001/jamapsychiatry.2015.0554

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

M.H.M. de Moor, S.M. van den Berg, C.J.H. Verweij, R.F. Krueger, M. Luciano, A. Arias-Vasquez, L.K. Matteson, J. Derringer, T. Esko, N. Amin, S.D. Gordon, N.K. Hansell, A.B. Hart, I. Seppälä, J.E. Huffman, B. Konte, J. Lahti, M.Y. Lee, M. Miller, T. NutileT. Tanaka, A. Teumer, A. Viktorin, J. Wedenoja, G.R. Abecasis, D.E. Adkins, A. Agrawal, J. Allik, K. Appel, T.B. Bigdeli, F. Busonero, H. Campbell, P.T. Costa, G. Davey Smith, G. Davies, H. de Wit, J. Ding, B.E. Engelhardt, J.G. Eriksson, I.O. Fedko, L. Ferrucci, B. Franke, I. Giegling, R. Grucza, A.M. Hartmann, A.C. Heath, K. Heinonen, A.K. Henders, G. Homuth, J.J. Hottenga, W.G. Iacono, J. Janzing, M Jokela, R. Karlsson, J.P. Kemp, M.G. Kirkpatrick, A. Latvala, T. Lehtimäki, D.C. Liewald, P.A.F. Madden, C. Magri, P.K.E. Magnusson, J. Marten, A. Maschio, S.E. Medland, E. Mihailov, Y. Milaneschi, G.W. Montgomery, M. Nauck, K.G. Ouwens, A. Palotie, E. Pettersson, O. Polasek, Y. Qian, L. Pulkki-Råback, O.T. Raitakari, A. Realo, R.J. Rose, D. Ruggiero, C.O. Schmidt, W.S. Slutske, R. Sorice, J.M. Starr, B. St Pourcain, A.R. Sutin, N.J. Timpson, H. Trochet, S. Vermeulen, E. Vuoksimaa, E. Widén, J. Wouda, M.J. Wright, L. Zgaga, D. Porteous, A. Minelli, A.A. Palmer, D. Rujescu, M. Ciullo, C. Hayward, I. Rudan, A. Metspalu, J. Kaprio, I.J. Deary, K. Räikkönen, J.F. Wilson, L. Keltikangas-Järvinen, L.J. Bierut, J.M. Hettema, H.J. Grabe, C.M. van Duijn, D.M. Evans, D. Schlessinger, N.L. Pedersen, A. Terracciano, M. McGue, B.W.J.H. Penninx, N.G. Martin, D.I. Boomsma

Psychiatry

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	642-650
Number of pages	9
Journal	JAMA Psychiatry
Volume	72
Issue number	7
DOIs	https://doi.org/10.1001/jamapsychiatry.2015.0554
Publication status	Published - 2015

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10.1001/jamapsychiatry.2015.0554

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de Moor, M. H. M., van den Berg, S. M., Verweij, C. J. H., Krueger, R. F., Luciano, M., Arias-Vasquez, A., ... Boomsma, D. I. (2015). Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry, 72(7), 642-650. https://doi.org/10.1001/jamapsychiatry.2015.0554

de Moor, M.H.M. ; van den Berg, S.M. ; Verweij, C.J.H. ; Krueger, R.F. ; Luciano, M. ; Arias-Vasquez, A. ; Matteson, L.K. ; Derringer, J. ; Esko, T. ; Amin, N. ; Gordon, S.D. ; Hansell, N.K. ; Hart, A.B. ; Seppälä, I. ; Huffman, J.E. ; Konte, B. ; Lahti, J. ; Lee, M.Y. ; Miller, M. ; Nutile, T. ; Tanaka, T. ; Teumer, A. ; Viktorin, A. ; Wedenoja, J. ; Abecasis, G.R. ; Adkins, D.E. ; Agrawal, A. ; Allik, J. ; Appel, K. ; Bigdeli, T.B. ; Busonero, F. ; Campbell, H. ; Costa, P.T. ; Davey Smith, G. ; Davies, G. ; de Wit, H. ; Ding, J. ; Engelhardt, B.E. ; Eriksson, J.G. ; Fedko, I.O. ; Ferrucci, L. ; Franke, B. ; Giegling, I. ; Grucza, R. ; Hartmann, A.M. ; Heath, A.C. ; Heinonen, K. ; Henders, A.K. ; Homuth, G. ; Hottenga, J.J. ; Iacono, W.G. ; Janzing, J. ; Jokela, M ; Karlsson, R. ; Kemp, J.P. ; Kirkpatrick, M.G. ; Latvala, A. ; Lehtimäki, T. ; Liewald, D.C. ; Madden, P.A.F. ; Magri, C. ; Magnusson, P.K.E. ; Marten, J. ; Maschio, A. ; Medland, S.E. ; Mihailov, E. ; Milaneschi, Y. ; Montgomery, G.W. ; Nauck, M. ; Ouwens, K.G. ; Palotie, A. ; Pettersson, E. ; Polasek, O. ; Qian, Y. ; Pulkki-Råback, L. ; Raitakari, O.T. ; Realo, A. ; Rose, R.J. ; Ruggiero, D. ; Schmidt, C.O. ; Slutske, W.S. ; Sorice, R. ; Starr, J.M. ; St Pourcain, B. ; Sutin, A.R. ; Timpson, N.J. ; Trochet, H. ; Vermeulen, S. ; Vuoksimaa, E. ; Widén, E. ; Wouda, J. ; Wright, M.J. ; Zgaga, L. ; Porteous, D. ; Minelli, A. ; Palmer, A.A. ; Rujescu, D. ; Ciullo, M. ; Hayward, C. ; Rudan, I. ; Metspalu, A. ; Kaprio, J. ; Deary, I.J. ; Räikkönen, K. ; Wilson, J.F. ; Keltikangas-Järvinen, L. ; Bierut, L.J. ; Hettema, J.M. ; Grabe, H.J. ; van Duijn, C.M. ; Evans, D.M. ; Schlessinger, D. ; Pedersen, N.L. ; Terracciano, A. ; McGue, M. ; Penninx, B.W.J.H. ; Martin, N.G. ; Boomsma, D.I. / Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. In: JAMA Psychiatry. 2015 ; Vol. 72, No. 7. pp. 642-650.

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title = "Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder",

author = "{de Moor}, M.H.M. and {van den Berg}, S.M. and C.J.H. Verweij and R.F. Krueger and M. Luciano and A. Arias-Vasquez and L.K. Matteson and J. Derringer and T. Esko and N. Amin and S.D. Gordon and N.K. Hansell and A.B. Hart and I. Sepp{\"a}l{\"a} and J.E. Huffman and B. Konte and J. Lahti and M.Y. Lee and M. Miller and T. Nutile and T. Tanaka and A. Teumer and A. Viktorin and J. Wedenoja and G.R. Abecasis and D.E. Adkins and A. Agrawal and J. Allik and K. Appel and T.B. Bigdeli and F. Busonero and H. Campbell and P.T. Costa and {Davey Smith}, G. and G. Davies and {de Wit}, H. and J. Ding and B.E. Engelhardt and J.G. Eriksson and I.O. Fedko and L. Ferrucci and B. Franke and I. Giegling and R. Grucza and A.M. Hartmann and A.C. Heath and K. Heinonen and A.K. Henders and G. Homuth and J.J. Hottenga and W.G. Iacono and J. Janzing and M Jokela and R. Karlsson and J.P. Kemp and M.G. Kirkpatrick and A. Latvala and T. Lehtim{\"a}ki and D.C. Liewald and P.A.F. Madden and C. Magri and P.K.E. Magnusson and J. Marten and A. Maschio and S.E. Medland and E. Mihailov and Y. Milaneschi and G.W. Montgomery and M. Nauck and K.G. Ouwens and A. Palotie and E. Pettersson and O. Polasek and Y. Qian and L. Pulkki-R{\aa}back and O.T. Raitakari and A. Realo and R.J. Rose and D. Ruggiero and C.O. Schmidt and W.S. Slutske and R. Sorice and J.M. Starr and {St Pourcain}, B. and A.R. Sutin and N.J. Timpson and H. Trochet and S. Vermeulen and E. Vuoksimaa and E. Wid{\'e}n and J. Wouda and M.J. Wright and L. Zgaga and D. Porteous and A. Minelli and A.A. Palmer and D. Rujescu and M. Ciullo and C. Hayward and I. Rudan and A. Metspalu and J. Kaprio and I.J. Deary and K. R{\"a}ikk{\"o}nen and J.F. Wilson and L. Keltikangas-J{\"a}rvinen and L.J. Bierut and J.M. Hettema and H.J. Grabe and {van Duijn}, C.M. and D.M. Evans and D. Schlessinger and N.L. Pedersen and A. Terracciano and M. McGue and B.W.J.H. Penninx and N.G. Martin and D.I. Boomsma",

year = "2015",

doi = "10.1001/jamapsychiatry.2015.0554",

language = "English",

volume = "72",

pages = "642--650",

journal = "JAMA Psychiatry",

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de Moor, MHM, van den Berg, SM, Verweij, CJH, Krueger, RF, Luciano, M, Arias-Vasquez, A, Matteson, LK, Derringer, J, Esko, T, Amin, N, Gordon, SD, Hansell, NK, Hart, AB, Seppälä, I, Huffman, JE, Konte, B, Lahti, J, Lee, MY, Miller, M, Nutile, T, Tanaka, T, Teumer, A, Viktorin, A, Wedenoja, J, Abecasis, GR, Adkins, DE, Agrawal, A, Allik, J, Appel, K, Bigdeli, TB, Busonero, F, Campbell, H, Costa, PT, Davey Smith, G, Davies, G, de Wit, H, Ding, J, Engelhardt, BE, Eriksson, JG, Fedko, IO, Ferrucci, L, Franke, B, Giegling, I, Grucza, R, Hartmann, AM, Heath, AC, Heinonen, K, Henders, AK, Homuth, G, Hottenga, JJ, Iacono, WG, Janzing, J, Jokela, M, Karlsson, R, Kemp, JP, Kirkpatrick, MG, Latvala, A, Lehtimäki, T, Liewald, DC, Madden, PAF, Magri, C, Magnusson, PKE, Marten, J, Maschio, A, Medland, SE, Mihailov, E, Milaneschi, Y, Montgomery, GW, Nauck, M, Ouwens, KG, Palotie, A, Pettersson, E, Polasek, O, Qian, Y, Pulkki-Råback, L, Raitakari, OT, Realo, A, Rose, RJ, Ruggiero, D, Schmidt, CO, Slutske, WS, Sorice, R, Starr, JM, St Pourcain, B, Sutin, AR, Timpson, NJ, Trochet, H, Vermeulen, S, Vuoksimaa, E, Widén, E, Wouda, J, Wright, MJ, Zgaga, L, Porteous, D, Minelli, A, Palmer, AA, Rujescu, D, Ciullo, M, Hayward, C, Rudan, I, Metspalu, A, Kaprio, J, Deary, IJ, Räikkönen, K, Wilson, JF, Keltikangas-Järvinen, L, Bierut, LJ, Hettema, JM, Grabe, HJ, van Duijn, CM, Evans, DM, Schlessinger, D, Pedersen, NL, Terracciano, A, McGue, M, Penninx, BWJH, Martin, NG & Boomsma, DI 2015, 'Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder', JAMA Psychiatry, vol. 72, no. 7, pp. 642-650. https://doi.org/10.1001/jamapsychiatry.2015.0554

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. / de Moor, M.H.M.; van den Berg, S.M.; Verweij, C.J.H.; Krueger, R.F.; Luciano, M.; Arias-Vasquez, A.; Matteson, L.K.; Derringer, J.; Esko, T.; Amin, N.; Gordon, S.D.; Hansell, N.K.; Hart, A.B.; Seppälä, I.; Huffman, J.E.; Konte, B.; Lahti, J.; Lee, M.Y.; Miller, M.; Nutile, T.; Tanaka, T.; Teumer, A.; Viktorin, A.; Wedenoja, J.; Abecasis, G.R.; Adkins, D.E.; Agrawal, A.; Allik, J.; Appel, K.; Bigdeli, T.B.; Busonero, F.; Campbell, H.; Costa, P.T.; Davey Smith, G.; Davies, G.; de Wit, H.; Ding, J.; Engelhardt, B.E.; Eriksson, J.G.; Fedko, I.O.; Ferrucci, L.; Franke, B.; Giegling, I.; Grucza, R.; Hartmann, A.M.; Heath, A.C.; Heinonen, K.; Henders, A.K.; Homuth, G.; Hottenga, J.J.; Iacono, W.G.; Janzing, J.; Jokela, M; Karlsson, R.; Kemp, J.P.; Kirkpatrick, M.G.; Latvala, A.; Lehtimäki, T.; Liewald, D.C.; Madden, P.A.F.; Magri, C.; Magnusson, P.K.E.; Marten, J.; Maschio, A.; Medland, S.E.; Mihailov, E.; Milaneschi, Y.; Montgomery, G.W.; Nauck, M.; Ouwens, K.G.; Palotie, A.; Pettersson, E.; Polasek, O.; Qian, Y.; Pulkki-Råback, L.; Raitakari, O.T.; Realo, A.; Rose, R.J.; Ruggiero, D.; Schmidt, C.O.; Slutske, W.S.; Sorice, R.; Starr, J.M.; St Pourcain, B.; Sutin, A.R.; Timpson, N.J.; Trochet, H.; Vermeulen, S.; Vuoksimaa, E.; Widén, E.; Wouda, J.; Wright, M.J.; Zgaga, L.; Porteous, D.; Minelli, A.; Palmer, A.A.; Rujescu, D.; Ciullo, M.; Hayward, C.; Rudan, I.; Metspalu, A.; Kaprio, J.; Deary, I.J.; Räikkönen, K.; Wilson, J.F.; Keltikangas-Järvinen, L.; Bierut, L.J.; Hettema, J.M.; Grabe, H.J.; van Duijn, C.M.; Evans, D.M.; Schlessinger, D.; Pedersen, N.L.; Terracciano, A.; McGue, M.; Penninx, B.W.J.H.; Martin, N.G.; Boomsma, D.I.

In: JAMA Psychiatry, Vol. 72, No. 7, 2015, p. 642-650.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

AU - de Moor, M.H.M.

AU - van den Berg, S.M.

AU - Verweij, C.J.H.

AU - Krueger, R.F.

AU - Luciano, M.

AU - Arias-Vasquez, A.

AU - Matteson, L.K.

AU - Derringer, J.

AU - Esko, T.

AU - Amin, N.

AU - Gordon, S.D.

AU - Hansell, N.K.

AU - Hart, A.B.

AU - Seppälä, I.

AU - Huffman, J.E.

AU - Konte, B.

AU - Lahti, J.

AU - Lee, M.Y.

AU - Miller, M.

AU - Nutile, T.

AU - Tanaka, T.

AU - Teumer, A.

AU - Viktorin, A.

AU - Wedenoja, J.

AU - Abecasis, G.R.

AU - Adkins, D.E.

AU - Agrawal, A.

AU - Allik, J.

AU - Appel, K.

AU - Bigdeli, T.B.

AU - Busonero, F.

AU - Campbell, H.

AU - Costa, P.T.

AU - Davey Smith, G.

AU - Davies, G.

AU - de Wit, H.

AU - Ding, J.

AU - Engelhardt, B.E.

AU - Eriksson, J.G.

AU - Fedko, I.O.

AU - Ferrucci, L.

AU - Franke, B.

AU - Giegling, I.

AU - Grucza, R.

AU - Hartmann, A.M.

AU - Heath, A.C.

AU - Heinonen, K.

AU - Henders, A.K.

AU - Homuth, G.

AU - Hottenga, J.J.

AU - Iacono, W.G.

AU - Janzing, J.

AU - Jokela, M

AU - Karlsson, R.

AU - Kemp, J.P.

AU - Kirkpatrick, M.G.

AU - Latvala, A.

AU - Lehtimäki, T.

AU - Liewald, D.C.

AU - Madden, P.A.F.

AU - Magri, C.

AU - Magnusson, P.K.E.

AU - Marten, J.

AU - Maschio, A.

AU - Medland, S.E.

AU - Mihailov, E.

AU - Milaneschi, Y.

AU - Montgomery, G.W.

AU - Nauck, M.

AU - Ouwens, K.G.

AU - Palotie, A.

AU - Pettersson, E.

AU - Polasek, O.

AU - Qian, Y.

AU - Pulkki-Råback, L.

AU - Raitakari, O.T.

AU - Realo, A.

AU - Rose, R.J.

AU - Ruggiero, D.

AU - Schmidt, C.O.

AU - Slutske, W.S.

AU - Sorice, R.

AU - Starr, J.M.

AU - St Pourcain, B.

AU - Sutin, A.R.

AU - Timpson, N.J.

AU - Trochet, H.

AU - Vermeulen, S.

AU - Vuoksimaa, E.

AU - Widén, E.

AU - Wouda, J.

AU - Wright, M.J.

AU - Zgaga, L.

AU - Porteous, D.

AU - Minelli, A.

AU - Palmer, A.A.

AU - Rujescu, D.

AU - Ciullo, M.

AU - Hayward, C.

AU - Rudan, I.

AU - Metspalu, A.

AU - Kaprio, J.

AU - Deary, I.J.

AU - Räikkönen, K.

AU - Wilson, J.F.

AU - Keltikangas-Järvinen, L.

AU - Bierut, L.J.

AU - Hettema, J.M.

AU - Grabe, H.J.

AU - van Duijn, C.M.

AU - Evans, D.M.

AU - Schlessinger, D.

AU - Pedersen, N.L.

AU - Terracciano, A.

AU - McGue, M.

AU - Penninx, B.W.J.H.

AU - Martin, N.G.

AU - Boomsma, D.I.

PY - 2015

Y1 - 2015

U2 - 10.1001/jamapsychiatry.2015.0554

DO - 10.1001/jamapsychiatry.2015.0554

M3 - Article

C2 - 25993607

VL - 72

SP - 642

EP - 650

JO - JAMA Psychiatry

JF - JAMA Psychiatry

SN - 2168-622X

IS - 7

ER -