Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality

Emma J. de Louw, Nadine P.G. Paans, Caroline M. Sonnenberg, Hugo Konz, Paul David Meesters, Daniel van Grootheest, Mardien L. Oudega, Didi Rhebergen, Cora Kerssens, Hannie C. Comijs, Max L. Stek, Annemiek Dols

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of 98 patients (98%); nine patients had died. Parameters of MS were available of 76 patients; 34.2% were diagnosed with MS. This was not significantly different compared with baseline (46.1%). MS at baseline was not significantly associated with mortality or development of diabetes at follow-up. Conclusions: In older patients with SMI, the rates of MS may reach a plateau. Screening for MS in older patients treated at a specialized mental health outpatient clinic may generate attention for their somatic health and treatment for the components of MS that may in turn have a positive effect on their outcome. However, further research with larger sample sizes is needed in order to confirm these findings.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalInternational Journal of Geriatric Psychiatry
Volume34
Issue number2
DOIs
Publication statusPublished - 1 Jan 2019

Cite this

@article{2198707759f04a14ae667c2989f61978,
title = "Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality",
abstract = "Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of 98 patients (98{\%}); nine patients had died. Parameters of MS were available of 76 patients; 34.2{\%} were diagnosed with MS. This was not significantly different compared with baseline (46.1{\%}). MS at baseline was not significantly associated with mortality or development of diabetes at follow-up. Conclusions: In older patients with SMI, the rates of MS may reach a plateau. Screening for MS in older patients treated at a specialized mental health outpatient clinic may generate attention for their somatic health and treatment for the components of MS that may in turn have a positive effect on their outcome. However, further research with larger sample sizes is needed in order to confirm these findings.",
keywords = "elderly, metabolic screening, metabolic syndrome, mortality, severe mental illness",
author = "{de Louw}, {Emma J.} and Paans, {Nadine P.G.} and Sonnenberg, {Caroline M.} and Hugo Konz and Meesters, {Paul David} and {van Grootheest}, Daniel and Oudega, {Mardien L.} and Didi Rhebergen and Cora Kerssens and Comijs, {Hannie C.} and Stek, {Max L.} and Annemiek Dols",
year = "2019",
month = "1",
day = "1",
doi = "10.1002/gps.5025",
language = "English",
volume = "34",
pages = "333--336",
journal = "International Journal of Geriatric Psychiatry",
issn = "0885-6230",
publisher = "John Wiley and Sons Ltd",
number = "2",

}

Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality. / de Louw, Emma J.; Paans, Nadine P.G.; Sonnenberg, Caroline M.; Konz, Hugo; Meesters, Paul David; van Grootheest, Daniel; Oudega, Mardien L.; Rhebergen, Didi; Kerssens, Cora; Comijs, Hannie C.; Stek, Max L.; Dols, Annemiek.

In: International Journal of Geriatric Psychiatry, Vol. 34, No. 2, 01.01.2019, p. 333-336.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality

AU - de Louw, Emma J.

AU - Paans, Nadine P.G.

AU - Sonnenberg, Caroline M.

AU - Konz, Hugo

AU - Meesters, Paul David

AU - van Grootheest, Daniel

AU - Oudega, Mardien L.

AU - Rhebergen, Didi

AU - Kerssens, Cora

AU - Comijs, Hannie C.

AU - Stek, Max L.

AU - Dols, Annemiek

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of 98 patients (98%); nine patients had died. Parameters of MS were available of 76 patients; 34.2% were diagnosed with MS. This was not significantly different compared with baseline (46.1%). MS at baseline was not significantly associated with mortality or development of diabetes at follow-up. Conclusions: In older patients with SMI, the rates of MS may reach a plateau. Screening for MS in older patients treated at a specialized mental health outpatient clinic may generate attention for their somatic health and treatment for the components of MS that may in turn have a positive effect on their outcome. However, further research with larger sample sizes is needed in order to confirm these findings.

AB - Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of 98 patients (98%); nine patients had died. Parameters of MS were available of 76 patients; 34.2% were diagnosed with MS. This was not significantly different compared with baseline (46.1%). MS at baseline was not significantly associated with mortality or development of diabetes at follow-up. Conclusions: In older patients with SMI, the rates of MS may reach a plateau. Screening for MS in older patients treated at a specialized mental health outpatient clinic may generate attention for their somatic health and treatment for the components of MS that may in turn have a positive effect on their outcome. However, further research with larger sample sizes is needed in order to confirm these findings.

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