Metabolic syndrome rates in older patients with severe mental illness after five years of follow-up and the association with mortality

Emma J. de Louw*, Nadine P.G. Paans, Caroline M. Sonnenberg, Hugo Konz, Paul David Meesters, Daniel van Grootheest, Mardien L. Oudega, Didi Rhebergen, Cora Kerssens, Hannie C. Comijs, Max L. Stek, Annemiek Dols

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Objectives: To establish the course of metabolic syndrome (MS) rates in older patients with severe mental illness (SMI) after 5-year follow-up and evaluate whether MS at baseline is associated with mortality or diabetes at follow-up. Methods: Patients (>60 years of age) with SMI (N = 100) were included at a specialized mental health outpatient clinic. Metabolic parameters were collected from patients' medical files at baseline and after 5-year follow-up. Results: Follow-up data were available of 98 patients (98%); nine patients had died. Parameters of MS were available of 76 patients; 34.2% were diagnosed with MS. This was not significantly different compared with baseline (46.1%). MS at baseline was not significantly associated with mortality or development of diabetes at follow-up. Conclusions: In older patients with SMI, the rates of MS may reach a plateau. Screening for MS in older patients treated at a specialized mental health outpatient clinic may generate attention for their somatic health and treatment for the components of MS that may in turn have a positive effect on their outcome. However, further research with larger sample sizes is needed in order to confirm these findings.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalInternational Journal of Geriatric Psychiatry
Issue number2
Publication statusPublished - 1 Feb 2019

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