Method for conditioning stem cells.

Antoni Bayes Genis (Inventor), Aida Llucia Valldeperas (Inventor), Carolina Soler Botija (Inventor), Ramon Bragos Bardia (Inventor), Francesc Xavier. Rosell Ferrer (Inventor)

Research output: PatentAcademic

Abstract

There is provided a method of stimulating an isolated stem cell comprising two stimulation steps: (a) cell mech. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more mech. pulses having a stretching value comprised from 5% to 15%, and a duration of time comprised from 300 to 700 ms, at a frequency comprised from 0.5 to 1.5 Hz; and (b) cell elec. stimulation which comprises the application, to a culture medium comprising the isolated stem cells, of one or more elec. pulses having a potential value comprised from 0mv/cm to 1000mv/cm, and a duration of time comprised from 1 to 3 ms, at a frequency comprised from 0.5 to 1.5 Hz. There is also provided the cell obtainable by the method, further products comprising the cell such as solns. and scaffolds, and its uses in tissue engineering and regenerative therapy. [on SciFinder(R)]
Original languageEnglish
Patent numberWO2017125159A1
Publication statusPublished - 2017

Cite this

Bayes Genis, A., Llucia Valldeperas, A., Soler Botija, C., Bragos Bardia, R., & Rosell Ferrer, F. X. (2017). Method for conditioning stem cells. (Patent No. WO2017125159A1). Universitat Politecnica de Catalunya, Spain; Fundacio Institut d'Investigacio en Ciencies de la Salut Germans Trias I Pujol .