TY - JOUR
T1 - Methods to assess fat mass in infants and young children
T2 - A comparative study using skinfold thickness and air-displacement plethysmography
AU - Kouwenhoven, Stefanie M.P.
AU - Antl, Nadja
AU - Twisk, Jos W.R.
AU - Koletzko, Berthold V.
AU - Finken, Martijn J.J.
AU - van Goudoever, Johannes B.
N1 - Funding Information:
Funding: The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007–2013), project EarlyNutrition under grant agreement no. 289346 and the European Research Council Advanced Grant META-GROWTH ERC-2012-AdG– no. 322605. The work of BK is supported by the Else Kröner-Seniorprofessorship of Paediatrics cofunded by the Else Kröner-Fresenius-Foundation, Bad Homburg, Germany and the LMU University Hospitals.
Funding Information:
The research leading to these results has received funding from the European Union?s Seventh Framework Programme (FP7/2007?2013), project EarlyNutrition under grant agreement no. 289346 and the European Research Council Advanced Grant META-GROWTH ERC-2012-AdG? no. 322605. The work of BK is supported by the Else Kr?ner-Seniorprofessorship of Paediatrics cofunded by the Else Kr?ner-Fresenius-Foundation, Bad Homburg, Germany and the LMU University Hospitals.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/2
Y1 - 2021/2
N2 - Background: Traditionally, fat mass is estimated using anthropometric models. Airdisplacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infants and young children. Therefore we aimed to longitudinally compare fat mass percentage values predicted from skinfold thicknesses (SFTs) and ADP in healthy infants and young children. Methods: Anthropometry and body composition were determined at the ages of 1, 4, and 6 months and 2 years. We quantified the agreement between the two methods using the Bland–Altman procedure, linear mixed-model analysis, and intra-class correlation coefficients (ICC). Results: During the first 6 months of life, fat mass% predicted with SFT was significantly different from that measured with ADP in healthy, term-born infants (n = 245). ICCs ranged from 0.33 (at 2 years of age) and 0.47 (at 4 months of age). Although the mean difference (bias) between the methods was low, the Bland–Altman plots showed proportional differences at all ages with wide limits of agreement. Conclusions: There is poor agreement between ADP and SFTs for estimating fat mass in infancy or early childhood. The amount of body fat was found to influence the agreement between the methods.
AB - Background: Traditionally, fat mass is estimated using anthropometric models. Airdisplacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infants and young children. Therefore we aimed to longitudinally compare fat mass percentage values predicted from skinfold thicknesses (SFTs) and ADP in healthy infants and young children. Methods: Anthropometry and body composition were determined at the ages of 1, 4, and 6 months and 2 years. We quantified the agreement between the two methods using the Bland–Altman procedure, linear mixed-model analysis, and intra-class correlation coefficients (ICC). Results: During the first 6 months of life, fat mass% predicted with SFT was significantly different from that measured with ADP in healthy, term-born infants (n = 245). ICCs ranged from 0.33 (at 2 years of age) and 0.47 (at 4 months of age). Although the mean difference (bias) between the methods was low, the Bland–Altman plots showed proportional differences at all ages with wide limits of agreement. Conclusions: There is poor agreement between ADP and SFTs for estimating fat mass in infancy or early childhood. The amount of body fat was found to influence the agreement between the methods.
KW - Adiposity
KW - Anthropometric model
KW - Body composition
KW - Body composition assessment
KW - Body fat
KW - Fat mass percentage
KW - Growth
UR - http://www.scopus.com/inward/record.url?scp=85099808973&partnerID=8YFLogxK
U2 - 10.3390/life11020075
DO - 10.3390/life11020075
M3 - Article
C2 - 33498272
AN - SCOPUS:85099808973
VL - 11
SP - 1
EP - 9
JO - Life
JF - Life
SN - 2075-1729
IS - 2
M1 - 75
ER -