Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]

Marc Besselink; Marja Boermeester; Thomas Bollen; Erik Buskens; Esther Consten; Miguel Cuesta; Cornelis de Jong; Ralph de Wit; Hein Gooszen; Dirk Gouma; Eric Hesselink; Sijbrand Hofker; Lex Houdijk; Tom Karsten

Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]

Marc Besselink, Marja Boermeester, Thomas Bollen, Erik Buskens, Esther Consten, Miguel Cuesta, Cornelis de Jong, Ralph de Wit, Hein Gooszen, Dirk Gouma, Eric Hesselink, Sijbrand Hofker, Lex Houdijk, Tom Karsten

VU University medical center

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

BACKGROUND:The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision.

Original language	English
Pages (from-to)	6
Journal	BMC Surgery
Volume	6
Issue number	1
Publication status	Published - 2006

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Besselink, M., Boermeester, M., Bollen, T., Buskens, E., Consten, E., Cuesta, M., de Jong, C., de Wit, R., Gooszen, H., Gouma, D., Hesselink, E., Hofker, S., Houdijk, L., & Karsten, T. (2006). Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]. BMC Surgery, 6(1), 6.

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abstract = "BACKGROUND:The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision.",

author = "Marc Besselink and Marja Boermeester and Thomas Bollen and Erik Buskens and Esther Consten and Miguel Cuesta and {de Jong}, Cornelis and {de Wit}, Ralph and Hein Gooszen and Dirk Gouma and Eric Hesselink and Sijbrand Hofker and Lex Houdijk and Tom Karsten",

year = "2006",

language = "English",

volume = "6",

pages = "6",

journal = "BMC Surgery",

issn = "1471-2482",

publisher = "BioMed Central",

number = "1",

}

Besselink, M, Boermeester, M, Bollen, T, Buskens, E, Consten, E, Cuesta, M, de Jong, C, de Wit, R, Gooszen, H, Gouma, D, Hesselink, E, Hofker, S, Houdijk, L & Karsten, T 2006, 'Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]', BMC Surgery, vol. 6, no. 1, pp. 6.

Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]. / Besselink, Marc; Boermeester, Marja; Bollen, Thomas et al.
In: BMC Surgery, Vol. 6, No. 1, 2006, p. 6.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN38327949]

AU - Besselink, Marc

AU - Boermeester, Marja

AU - Bollen, Thomas

AU - Buskens, Erik

AU - Consten, Esther

AU - Cuesta, Miguel

AU - de Jong, Cornelis

AU - de Wit, Ralph

AU - Gooszen, Hein

AU - Gouma, Dirk

AU - Hesselink, Eric

AU - Hofker, Sijbrand

AU - Houdijk, Lex

AU - Karsten, Tom

PY - 2006

Y1 - 2006

N2 - BACKGROUND:The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision.

AB - BACKGROUND:The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the Netherlands, the standard intervention is necrosectomy by laparotomy followed by continuous postoperative lavage (CPL). In recent years several minimally invasive strategies have been introduced. So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision.

M3 - Article

SN - 1471-2482

VL - 6

SP - 6

JO - BMC Surgery

JF - BMC Surgery

IS - 1

ER -