MR Imaging of Joint Infection and Inflammation with Emphasis on Dynamic Contrast-Enhanced MR Imaging

Mikael Boesen, Olga Kubassova, Iwona Sudoł-Szopińska, Mario Maas, Philip Hansen, Janus Damm Nybing, Edwin H Oei, Robert Hemke, Ali Guermazi

Research output: Contribution to journalReview articleAcademicpeer-review


Contrast-enhanced MR imaging (CE-MR imaging) is recommended for diagnosis and monitoring of infectious and most inflammatory joint diseases. CE-MR imaging clearly differentiates soft and bony tissue from fluid collections and infectious debris. To improve imaging information, a dynamic CE-MR imaging sequence (DCE-MR imaging) sequence can be applied using fast T1-weighted sequential image acquisition during contrast injection. Use of DCE-MR imaging allows robust extraction of quantitative information regarding blood flow and capillary permeability, especially when dedicated analysis methods and software are used to analyze contrast kinetics. This article describes principles of DCE-MR imaging for the assessment of infectious and inflammatory joint diseases.

Original languageEnglish
Pages (from-to)523-550
Number of pages28
JournalPET Clinics
Issue number4
Publication statusPublished - Oct 2018

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