MRI-guided immunotherapy development for multiple sclerosis in a primate

Bert A 't Hart, Paul Smith, Sandra Amor, Gustav J Strijkers, Erwin L A Blezer

Research output: Contribution to journalReview articleAcademicpeer-review


Multiple sclerosis is a serious neurological disease that affects 1 in 1000 young adults in Europe and the USA. The development of an effective therapy for this enigmatic disease is plagued by the failure of many treatments to reproduce in patients the promising effects observed in animal models. This review describes a new preclinical model in a non-human primate that might help to bridge the gap between currently used animal models and the patients.

Original languageEnglish
Pages (from-to)58-66
Number of pages9
JournalDrug Discovery Today
Issue number1-2
Publication statusPublished - Jan 2006

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