Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

L. Paternoster; M. Standl; J. Waage; H. Baurecht; M. Hotze; D.P. Strachan; J.A. Curtin; K. Bonnelykke; C. Tian; A. Takahashi; J. Esparza-Gordillo; A.C. Alves; J.P. Thyssen; H.T. den Dekker; M.A. Ferreira; E. Altmaier; P.M.A. Sleiman; F.L. Xiao; J.R. Gonzalez; I. Marenholz; B. Kalb; M. Pino-Yanes; C. Xu; L. Carstensen; M.M. Groen-Blokhuis; C. Venturini; C.E. Pennell; S.J. Barton; A.M. Levin; I. Curjuric; M. Bustamante; E. Kreiner-Moller; G.A. Lockett; J. Bacelis; S. Bunyavanich; R.A. Myers; A. Matanovic; A. Kumar; J.Y. Tung; T. Hirota; M. Kubo; W.L. McArdle; A.J. Henderson; J.P. Kemp; J. Zheng; G.D. Smith; F. Rueschendorf; A. Bauerfeind; M.A. Lee-Kirsch; A. Arnold; G. Homuth; C.O. Schmidt; E. Mangold; S. Cichon; T. Keil; E. Rodriguez; A. Peters; A. Franke; W. Lieb; N. Novak; R. Foelster-Holst; M. Horikoshi; J. Pekkanen; S. Sebert; L.L. Husemoen; N. Grarup; J.C. de Jongste; F. Rivadeneira; A. Hofman; V.W.V. Jaddoe; S.G.M.A. Pasmans; N.J. Elbert; A. G. Uitterlinden; G.B. Marks; P.J. Thompson; M.C. Matheson; C.F. Robertson; J.S. Ried; J. Li; X.B. Zuo; X.D. Zheng; X.Y. Yin; L.D. Sun; M.A. McAleer; G.M. O'Regan; C.M.R. Fahy; L.E. Campbell; M. Macek; M. Kurek; D. Hu; C. Eng; D.S. Postma; B. Feenstra; F. Geller; J.J. Hottenga; C.M. Middeldorp; P. Hysi; V. Bataille; T. Spector; C.M.T. Tiesler; E. Thiering; B. Pahukasahasram; J.J. Yang; M. Imboden; S. Huntsman; N. Vilor-Tejedor; C.L. Relton; R. Myhre; W. Nystad; A. Custovic; S.T. Weiss; D.A. Meyers; C. Soederhaell; E. Melen; C. Ober; B.A. Raby; A. Simpson; B. Jacobsson; J.W. Holloway; H. Bisgaard; J. Sunyer; N.M. Probst-Hensch; L.K. Williams; K.M. Godfrey; C.A. Wang; D.I. Boomsma; M. Melbye; G.H. Koppelman; D. Jarvis; W.H.I. McLean; A.D. Irvine; X.J. Zhang; H. Hakonarson; C. Gieger; E.G. Burchard; N.G. Martin; L. Duijts; A. Linneberg; M. Jarvelin; M.M. Noethen; S. Lau; N. Huebner; Y. Lee; M. Tamari; D.A. Hinds; D. Glass; S.J. Brown; J. Heinrich; D.M. Evans; S. Weidinger

doi:10.1038/ng.3424

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

L. Paternoster, M. Standl, J. Waage, H. Baurecht, M. Hotze, D.P. Strachan, J.A. Curtin, K. Bonnelykke, C. Tian, A. Takahashi, J. Esparza-Gordillo, A.C. Alves, J.P. Thyssen, H.T. den Dekker, M.A. Ferreira, E. Altmaier, P.M.A. Sleiman, F.L. Xiao, J.R. Gonzalez, I. MarenholzB. Kalb, M. Pino-Yanes, C. Xu, L. Carstensen, M.M. Groen-Blokhuis, C. Venturini, C.E. Pennell, S.J. Barton, A.M. Levin, I. Curjuric, M. Bustamante, E. Kreiner-Moller, G.A. Lockett, J. Bacelis, S. Bunyavanich, R.A. Myers, A. Matanovic, A. Kumar, J.Y. Tung, T. Hirota, M. Kubo, W.L. McArdle, A.J. Henderson, J.P. Kemp, J. Zheng, G.D. Smith, F. Rueschendorf, A. Bauerfeind, M.A. Lee-Kirsch, A. Arnold, G. Homuth, C.O. Schmidt, E. Mangold, S. Cichon, T. Keil, E. Rodriguez, A. Peters, A. Franke, W. Lieb, N. Novak, R. Foelster-Holst, M. Horikoshi, J. Pekkanen, S. Sebert, L.L. Husemoen, N. Grarup, J.C. de Jongste, F. Rivadeneira, A. Hofman, V.W.V. Jaddoe, S.G.M.A. Pasmans, N.J. Elbert, A. G. Uitterlinden, G.B. Marks, P.J. Thompson, M.C. Matheson, C.F. Robertson, J.S. Ried, J. Li, X.B. Zuo, X.D. Zheng, X.Y. Yin, L.D. Sun, M.A. McAleer, G.M. O'Regan, C.M.R. Fahy, L.E. Campbell, M. Macek, M. Kurek, D. Hu, C. Eng, D.S. Postma, B. Feenstra, F. Geller, J.J. Hottenga, C.M. Middeldorp, P. Hysi, V. Bataille, T. Spector, C.M.T. Tiesler, E. Thiering, B. Pahukasahasram, J.J. Yang, M. Imboden, S. Huntsman, N. Vilor-Tejedor, C.L. Relton, R. Myhre, W. Nystad, A. Custovic, S.T. Weiss, D.A. Meyers, C. Soederhaell, E. Melen, C. Ober, B.A. Raby, A. Simpson, B. Jacobsson, J.W. Holloway, H. Bisgaard, J. Sunyer, N.M. Probst-Hensch, L.K. Williams, K.M. Godfrey, C.A. Wang, D.I. Boomsma, M. Melbye, G.H. Koppelman, D. Jarvis, W.H.I. McLean, A.D. Irvine, X.J. Zhang, H. Hakonarson, C. Gieger, E.G. Burchard, N.G. Martin, L. Duijts, A. Linneberg, M. Jarvelin, M.M. Noethen, S. Lau, N. Huebner, Y. Lee, M. Tamari, D.A. Hinds, D. Glass, S.J. Brown, J. Heinrich, D.M. Evans, S. Weidinger

Psychiatry

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	1449-1456
Journal	Nature Genetics
Volume	47
Issue number	12
DOIs	https://doi.org/10.1038/ng.3424
Publication status	Published - 2015

Access to Document

10.1038/ng.3424

Cite this

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., ... Weidinger, S. (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics, 47(12), 1449-1456. https://doi.org/10.1038/ng.3424

@article{d354d61b393a424990bc0be5aeaa1fd3,

title = "Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis",

author = "L. Paternoster and M. Standl and J. Waage and H. Baurecht and M. Hotze and D.P. Strachan and J.A. Curtin and K. Bonnelykke and C. Tian and A. Takahashi and J. Esparza-Gordillo and A.C. Alves and J.P. Thyssen and {den Dekker}, H.T. and M.A. Ferreira and E. Altmaier and P.M.A. Sleiman and F.L. Xiao and J.R. Gonzalez and I. Marenholz and B. Kalb and M. Pino-Yanes and C. Xu and L. Carstensen and M.M. Groen-Blokhuis and C. Venturini and C.E. Pennell and S.J. Barton and A.M. Levin and I. Curjuric and M. Bustamante and E. Kreiner-Moller and G.A. Lockett and J. Bacelis and S. Bunyavanich and R.A. Myers and A. Matanovic and A. Kumar and J.Y. Tung and T. Hirota and M. Kubo and W.L. McArdle and A.J. Henderson and J.P. Kemp and J. Zheng and G.D. Smith and F. Rueschendorf and A. Bauerfeind and M.A. Lee-Kirsch and A. Arnold and G. Homuth and C.O. Schmidt and E. Mangold and S. Cichon and T. Keil and E. Rodriguez and A. Peters and A. Franke and W. Lieb and N. Novak and R. Foelster-Holst and M. Horikoshi and J. Pekkanen and S. Sebert and L.L. Husemoen and N. Grarup and {de Jongste}, J.C. and F. Rivadeneira and A. Hofman and V.W.V. Jaddoe and S.G.M.A. Pasmans and N.J. Elbert and Uitterlinden, {A. G.} and G.B. Marks and P.J. Thompson and M.C. Matheson and C.F. Robertson and J.S. Ried and J. Li and X.B. Zuo and X.D. Zheng and X.Y. Yin and L.D. Sun and M.A. McAleer and G.M. O'Regan and C.M.R. Fahy and L.E. Campbell and M. Macek and M. Kurek and D. Hu and C. Eng and D.S. Postma and B. Feenstra and F. Geller and J.J. Hottenga and C.M. Middeldorp and P. Hysi and V. Bataille and T. Spector and C.M.T. Tiesler and E. Thiering and B. Pahukasahasram and J.J. Yang and M. Imboden and S. Huntsman and N. Vilor-Tejedor and C.L. Relton and R. Myhre and W. Nystad and A. Custovic and S.T. Weiss and D.A. Meyers and C. Soederhaell and E. Melen and C. Ober and B.A. Raby and A. Simpson and B. Jacobsson and J.W. Holloway and H. Bisgaard and J. Sunyer and N.M. Probst-Hensch and L.K. Williams and K.M. Godfrey and C.A. Wang and D.I. Boomsma and M. Melbye and G.H. Koppelman and D. Jarvis and W.H.I. McLean and A.D. Irvine and X.J. Zhang and H. Hakonarson and C. Gieger and E.G. Burchard and N.G. Martin and L. Duijts and A. Linneberg and M. Jarvelin and M.M. Noethen and S. Lau and N. Huebner and Y. Lee and M. Tamari and D.A. Hinds and D. Glass and S.J. Brown and J. Heinrich and D.M. Evans and S. Weidinger",

year = "2015",

doi = "10.1038/ng.3424",

language = "Undefined/Unknown",

volume = "47",

pages = "1449--1456",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "12",

}

Paternoster, L, Standl, M, Waage, J, Baurecht, H, Hotze, M, Strachan, DP, Curtin, JA, Bonnelykke, K, Tian, C, Takahashi, A, Esparza-Gordillo, J, Alves, AC, Thyssen, JP, den Dekker, HT, Ferreira, MA, Altmaier, E, Sleiman, PMA, Xiao, FL, Gonzalez, JR, Marenholz, I, Kalb, B, Pino-Yanes, M, Xu, C, Carstensen, L, Groen-Blokhuis, MM, Venturini, C, Pennell, CE, Barton, SJ, Levin, AM, Curjuric, I, Bustamante, M, Kreiner-Moller, E, Lockett, GA, Bacelis, J, Bunyavanich, S, Myers, RA, Matanovic, A, Kumar, A, Tung, JY, Hirota, T, Kubo, M, McArdle, WL, Henderson, AJ, Kemp, JP, Zheng, J, Smith, GD, Rueschendorf, F, Bauerfeind, A, Lee-Kirsch, MA, Arnold, A, Homuth, G, Schmidt, CO, Mangold, E, Cichon, S, Keil, T, Rodriguez, E, Peters, A, Franke, A, Lieb, W, Novak, N, Foelster-Holst, R, Horikoshi, M, Pekkanen, J, Sebert, S, Husemoen, LL, Grarup, N, de Jongste, JC, Rivadeneira, F, Hofman, A, Jaddoe, VWV, Pasmans, SGMA, Elbert, NJ, Uitterlinden, AG, Marks, GB, Thompson, PJ, Matheson, MC, Robertson, CF, Ried, JS, Li, J, Zuo, XB, Zheng, XD, Yin, XY, Sun, LD, McAleer, MA, O'Regan, GM, Fahy, CMR, Campbell, LE, Macek, M, Kurek, M, Hu, D, Eng, C, Postma, DS, Feenstra, B, Geller, F, Hottenga, JJ, Middeldorp, CM, Hysi, P, Bataille, V, Spector, T, Tiesler, CMT, Thiering, E, Pahukasahasram, B, Yang, JJ, Imboden, M, Huntsman, S, Vilor-Tejedor, N, Relton, CL, Myhre, R, Nystad, W, Custovic, A, Weiss, ST, Meyers, DA, Soederhaell, C, Melen, E, Ober, C, Raby, BA, Simpson, A, Jacobsson, B, Holloway, JW, Bisgaard, H, Sunyer, J, Probst-Hensch, NM, Williams, LK, Godfrey, KM, Wang, CA, Boomsma, DI, Melbye, M, Koppelman, GH, Jarvis, D, McLean, WHI, Irvine, AD, Zhang, XJ, Hakonarson, H, Gieger, C, Burchard, EG, Martin, NG, Duijts, L, Linneberg, A, Jarvelin, M, Noethen, MM, Lau, S, Huebner, N, Lee, Y, Tamari, M, Hinds, DA, Glass, D, Brown, SJ, Heinrich, J, Evans, DM & Weidinger, S 2015, 'Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis', Nature Genetics, vol. 47, no. 12, pp. 1449-1456. https://doi.org/10.1038/ng.3424

TY - JOUR

T1 - Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

AU - Paternoster, L.

AU - Standl, M.

AU - Waage, J.

AU - Baurecht, H.

AU - Hotze, M.

AU - Strachan, D.P.

AU - Curtin, J.A.

AU - Bonnelykke, K.

AU - Tian, C.

AU - Takahashi, A.

AU - Esparza-Gordillo, J.

AU - Alves, A.C.

AU - Thyssen, J.P.

AU - den Dekker, H.T.

AU - Ferreira, M.A.

AU - Altmaier, E.

AU - Sleiman, P.M.A.

AU - Xiao, F.L.

AU - Gonzalez, J.R.

AU - Marenholz, I.

AU - Kalb, B.

AU - Pino-Yanes, M.

AU - Xu, C.

AU - Carstensen, L.

AU - Groen-Blokhuis, M.M.

AU - Venturini, C.

AU - Pennell, C.E.

AU - Barton, S.J.

AU - Levin, A.M.

AU - Curjuric, I.

AU - Bustamante, M.

AU - Kreiner-Moller, E.

AU - Lockett, G.A.

AU - Bacelis, J.

AU - Bunyavanich, S.

AU - Myers, R.A.

AU - Matanovic, A.

AU - Kumar, A.

AU - Tung, J.Y.

AU - Hirota, T.

AU - Kubo, M.

AU - McArdle, W.L.

AU - Henderson, A.J.

AU - Kemp, J.P.

AU - Zheng, J.

AU - Smith, G.D.

AU - Rueschendorf, F.

AU - Bauerfeind, A.

AU - Lee-Kirsch, M.A.

AU - Arnold, A.

AU - Homuth, G.

AU - Schmidt, C.O.

AU - Mangold, E.

AU - Cichon, S.

AU - Keil, T.

AU - Rodriguez, E.

AU - Peters, A.

AU - Franke, A.

AU - Lieb, W.

AU - Novak, N.

AU - Foelster-Holst, R.

AU - Horikoshi, M.

AU - Pekkanen, J.

AU - Sebert, S.

AU - Husemoen, L.L.

AU - Grarup, N.

AU - de Jongste, J.C.

AU - Rivadeneira, F.

AU - Hofman, A.

AU - Jaddoe, V.W.V.

AU - Pasmans, S.G.M.A.

AU - Elbert, N.J.

AU - Uitterlinden, A. G.

AU - Marks, G.B.

AU - Thompson, P.J.

AU - Matheson, M.C.

AU - Robertson, C.F.

AU - Ried, J.S.

AU - Li, J.

AU - Zuo, X.B.

AU - Zheng, X.D.

AU - Yin, X.Y.

AU - Sun, L.D.

AU - McAleer, M.A.

AU - O'Regan, G.M.

AU - Fahy, C.M.R.

AU - Campbell, L.E.

AU - Macek, M.

AU - Kurek, M.

AU - Hu, D.

AU - Eng, C.

AU - Postma, D.S.

AU - Feenstra, B.

AU - Geller, F.

AU - Hottenga, J.J.

AU - Middeldorp, C.M.

AU - Hysi, P.

AU - Bataille, V.

AU - Spector, T.

AU - Tiesler, C.M.T.

AU - Thiering, E.

AU - Pahukasahasram, B.

AU - Yang, J.J.

AU - Imboden, M.

AU - Huntsman, S.

AU - Vilor-Tejedor, N.

AU - Relton, C.L.

AU - Myhre, R.

AU - Nystad, W.

AU - Custovic, A.

AU - Weiss, S.T.

AU - Meyers, D.A.

AU - Soederhaell, C.

AU - Melen, E.

AU - Ober, C.

AU - Raby, B.A.

AU - Simpson, A.

AU - Jacobsson, B.

AU - Holloway, J.W.

AU - Bisgaard, H.

AU - Sunyer, J.

AU - Probst-Hensch, N.M.

AU - Williams, L.K.

AU - Godfrey, K.M.

AU - Wang, C.A.

AU - Boomsma, D.I.

AU - Melbye, M.

AU - Koppelman, G.H.

AU - Jarvis, D.

AU - McLean, W.H.I.

AU - Irvine, A.D.

AU - Zhang, X.J.

AU - Hakonarson, H.

AU - Gieger, C.

AU - Burchard, E.G.

AU - Martin, N.G.

AU - Duijts, L.

AU - Linneberg, A.

AU - Jarvelin, M.

AU - Noethen, M.M.

AU - Lau, S.

AU - Huebner, N.

AU - Lee, Y.

AU - Tamari, M.

AU - Hinds, D.A.

AU - Glass, D.

AU - Brown, S.J.

AU - Heinrich, J.

AU - Evans, D.M.

AU - Weidinger, S.

PY - 2015

Y1 - 2015

U2 - 10.1038/ng.3424

DO - 10.1038/ng.3424

M3 - Article

C2 - 26482879

VL - 47

SP - 1449

EP - 1456

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 12

ER -