New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm; Brent A. Orr; Umut H. Toprak; Volker Hovestadt; David T. W. Jones; David Capper; Martin Sill; Ivo Buchhalter; Paul A. Northcott; Irina Leis; Marina Ryzhova; Christian Koelsche; Elke Pfaff; Sariah J. Allen; Gnanaprakash Balasubramanian; Barbara C. Worst; Kristian W. Pajtler; Sebastian Brabetz; Pascal D. Johann; Felix Sahm; Jueri Reimand; Alan Mackay; Diana M. Carvalho; Marc Remke; Joanna J. Phillips; Arie Perry; Cynthia Cowdrey; Rachid Drissi; Maryam Fouladi; Felice Giangaspero; Maria Lastowska; Wieslawa Grajkowska; Wolfram Scheurlen; Torsten Pietsch; Christian Hagel; Johannes Gojo; Daniela Loetsch; Walter Berger; Irene Slavc; Christine Haberler; Anne Jouvet; Stefan Holm; Silvia Hofer; Marco Prinz; Catherine Keohane; Iris Fried; Christian Mawrin; David Scheie; Bret C. Mobley; Matthew J. Schniederjan; Mariarita Santi; Anna M. Buccoliero; Sonika Dahiya; Christof M. Kramm; Andre O. von Bueren; Katja von Hoff; Stefan Rutkowski; Christel Herold-Mende; Michael C. Fruehwald; Till Milde; Martin Hasselblatt; Pieter Wesseling; Jochen Roessler; Ulrich Schueller; Martin Ebinger; Jens Schittenhelm; Stephan Frank; Rainer Grobholz; Istvan Vajtai; Volkmar Hans; Reinhard Schneppenheim; Karel Zitterbart; V. Peter Collins; Eleonora Aronica; Pascale Varlet; Stephanie Puget; Christelle Dufour; Jacques Grill; Dominique Figarella-Branger; Marietta Wolter; Martin U. Schuhmann; Tarek Shalaby; Michael Grotzer; Timothy van Meter; Camelia-Maria Monoranu; Joerg Felsberg; Guido Reifenberger; Matija Snuderl; Lynn Ann Forrester; Jan Koster; Rogier Versteeg; Richard Volckmann; Peter van Sluis; Stephan Wolf; Tom Mikkelsen; Amar Gajjar; Kenneth Aldape; Andrew S. Moore; Michael D. Taylor; Chris Jones; Nada Jabado; Matthias A. Karajannis; Roland Eils; Matthias Schlesner; Peter Lichter; Andreas von Deimling; Stefan M. Pfister; David W. Ellison; Andrey Korshunov; Marcel Kool

doi:10.1016/j.cell.2016.01.015

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak, Volker Hovestadt, David T. W. Jones, David Capper, Martin Sill, Ivo Buchhalter, Paul A. Northcott, Irina Leis, Marina Ryzhova, Christian Koelsche, Elke Pfaff, Sariah J. Allen, Gnanaprakash Balasubramanian, Barbara C. Worst, Kristian W. Pajtler, Sebastian Brabetz, Pascal D. Johann, Felix SahmJueri Reimand, Alan Mackay, Diana M. Carvalho, Marc Remke, Joanna J. Phillips, Arie Perry, Cynthia Cowdrey, Rachid Drissi, Maryam Fouladi, Felice Giangaspero, Maria Lastowska, Wieslawa Grajkowska, Wolfram Scheurlen, Torsten Pietsch, Christian Hagel, Johannes Gojo, Daniela Loetsch, Walter Berger, Irene Slavc, Christine Haberler, Anne Jouvet, Stefan Holm, Silvia Hofer, Marco Prinz, Catherine Keohane, Iris Fried, Christian Mawrin, David Scheie, Bret C. Mobley, Matthew J. Schniederjan, Mariarita Santi, Anna M. Buccoliero, Sonika Dahiya, Christof M. Kramm, Andre O. von Bueren, Katja von Hoff, Stefan Rutkowski, Christel Herold-Mende, Michael C. Fruehwald, Till Milde, Martin Hasselblatt, Pieter Wesseling, Jochen Roessler, Ulrich Schueller, Martin Ebinger, Jens Schittenhelm, Stephan Frank, Rainer Grobholz, Istvan Vajtai, Volkmar Hans, Reinhard Schneppenheim, Karel Zitterbart, V. Peter Collins, Eleonora Aronica, Pascale Varlet, Stephanie Puget, Christelle Dufour, Jacques Grill, Dominique Figarella-Branger, Marietta Wolter, Martin U. Schuhmann, Tarek Shalaby, Michael Grotzer, Timothy van Meter, Camelia-Maria Monoranu, Joerg Felsberg, Guido Reifenberger, Matija Snuderl, Lynn Ann Forrester, Jan Koster, Rogier Versteeg, Richard Volckmann, Peter van Sluis, Stephan Wolf, Tom Mikkelsen, Amar Gajjar, Kenneth Aldape, Andrew S. Moore, Michael D. Taylor, Chris Jones, Nada Jabado, Matthias A. Karajannis, Roland Eils, Matthias Schlesner, Peter Lichter, Andreas von Deimling, Stefan M. Pfister, David W. Ellison, Andrey Korshunov, Marcel Kool

Pathology

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1060-1072
Journal	Cell
Volume	164
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2016.01.015
Publication status	Published - 25 Feb 2016

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10.1016/j.cell.2016.01.015

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Sturm, D., Orr, B. A., Toprak, U. H., Hovestadt, V., Jones, D. T. W., Capper, D., Sill, M., Buchhalter, I., Northcott, P. A., Leis, I., Ryzhova, M., Koelsche, C., Pfaff, E., Allen, S. J., Balasubramanian, G., Worst, B. C., Pajtler, K. W., Brabetz, S., Johann, P. D., ... Kool, M. (2016). New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell, 164(5), 1060-1072. https://doi.org/10.1016/j.cell.2016.01.015

Sturm, Dominik ; Orr, Brent A. ; Toprak, Umut H. ; Hovestadt, Volker ; Jones, David T. W. ; Capper, David ; Sill, Martin ; Buchhalter, Ivo ; Northcott, Paul A. ; Leis, Irina ; Ryzhova, Marina ; Koelsche, Christian ; Pfaff, Elke ; Allen, Sariah J. ; Balasubramanian, Gnanaprakash ; Worst, Barbara C. ; Pajtler, Kristian W. ; Brabetz, Sebastian ; Johann, Pascal D. ; Sahm, Felix ; Reimand, Jueri ; Mackay, Alan ; Carvalho, Diana M. ; Remke, Marc ; Phillips, Joanna J. ; Perry, Arie ; Cowdrey, Cynthia ; Drissi, Rachid ; Fouladi, Maryam ; Giangaspero, Felice ; Lastowska, Maria ; Grajkowska, Wieslawa ; Scheurlen, Wolfram ; Pietsch, Torsten ; Hagel, Christian ; Gojo, Johannes ; Loetsch, Daniela ; Berger, Walter ; Slavc, Irene ; Haberler, Christine ; Jouvet, Anne ; Holm, Stefan ; Hofer, Silvia ; Prinz, Marco ; Keohane, Catherine ; Fried, Iris ; Mawrin, Christian ; Scheie, David ; Mobley, Bret C. ; Schniederjan, Matthew J. ; Santi, Mariarita ; Buccoliero, Anna M. ; Dahiya, Sonika ; Kramm, Christof M. ; von Bueren, Andre O. ; von Hoff, Katja ; Rutkowski, Stefan ; Herold-Mende, Christel ; Fruehwald, Michael C. ; Milde, Till ; Hasselblatt, Martin ; Wesseling, Pieter ; Roessler, Jochen ; Schueller, Ulrich ; Ebinger, Martin ; Schittenhelm, Jens ; Frank, Stephan ; Grobholz, Rainer ; Vajtai, Istvan ; Hans, Volkmar ; Schneppenheim, Reinhard ; Zitterbart, Karel ; Collins, V. Peter ; Aronica, Eleonora ; Varlet, Pascale ; Puget, Stephanie ; Dufour, Christelle ; Grill, Jacques ; Figarella-Branger, Dominique ; Wolter, Marietta ; Schuhmann, Martin U. ; Shalaby, Tarek ; Grotzer, Michael ; van Meter, Timothy ; Monoranu, Camelia-Maria ; Felsberg, Joerg ; Reifenberger, Guido ; Snuderl, Matija ; Forrester, Lynn Ann ; Koster, Jan ; Versteeg, Rogier ; Volckmann, Richard ; van Sluis, Peter ; Wolf, Stephan ; Mikkelsen, Tom ; Gajjar, Amar ; Aldape, Kenneth ; Moore, Andrew S. ; Taylor, Michael D. ; Jones, Chris ; Jabado, Nada ; Karajannis, Matthias A. ; Eils, Roland ; Schlesner, Matthias ; Lichter, Peter ; von Deimling, Andreas ; Pfister, Stefan M. ; Ellison, David W. ; Korshunov, Andrey ; Kool, Marcel. / New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. In: Cell. 2016 ; Vol. 164, No. 5. pp. 1060-1072.

@article{663851bb830c458c91031afb636769b6,

title = "New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs",

author = "Dominik Sturm and Orr, {Brent A.} and Toprak, {Umut H.} and Volker Hovestadt and Jones, {David T. W.} and David Capper and Martin Sill and Ivo Buchhalter and Northcott, {Paul A.} and Irina Leis and Marina Ryzhova and Christian Koelsche and Elke Pfaff and Allen, {Sariah J.} and Gnanaprakash Balasubramanian and Worst, {Barbara C.} and Pajtler, {Kristian W.} and Sebastian Brabetz and Johann, {Pascal D.} and Felix Sahm and Jueri Reimand and Alan Mackay and Carvalho, {Diana M.} and Marc Remke and Phillips, {Joanna J.} and Arie Perry and Cynthia Cowdrey and Rachid Drissi and Maryam Fouladi and Felice Giangaspero and Maria Lastowska and Wieslawa Grajkowska and Wolfram Scheurlen and Torsten Pietsch and Christian Hagel and Johannes Gojo and Daniela Loetsch and Walter Berger and Irene Slavc and Christine Haberler and Anne Jouvet and Stefan Holm and Silvia Hofer and Marco Prinz and Catherine Keohane and Iris Fried and Christian Mawrin and David Scheie and Mobley, {Bret C.} and Schniederjan, {Matthew J.} and Mariarita Santi and Buccoliero, {Anna M.} and Sonika Dahiya and Kramm, {Christof M.} and {von Bueren}, {Andre O.} and {von Hoff}, Katja and Stefan Rutkowski and Christel Herold-Mende and Fruehwald, {Michael C.} and Till Milde and Martin Hasselblatt and Pieter Wesseling and Jochen Roessler and Ulrich Schueller and Martin Ebinger and Jens Schittenhelm and Stephan Frank and Rainer Grobholz and Istvan Vajtai and Volkmar Hans and Reinhard Schneppenheim and Karel Zitterbart and Collins, {V. Peter} and Eleonora Aronica and Pascale Varlet and Stephanie Puget and Christelle Dufour and Jacques Grill and Dominique Figarella-Branger and Marietta Wolter and Schuhmann, {Martin U.} and Tarek Shalaby and Michael Grotzer and {van Meter}, Timothy and Camelia-Maria Monoranu and Joerg Felsberg and Guido Reifenberger and Matija Snuderl and Forrester, {Lynn Ann} and Jan Koster and Rogier Versteeg and Richard Volckmann and {van Sluis}, Peter and Stephan Wolf and Tom Mikkelsen and Amar Gajjar and Kenneth Aldape and Moore, {Andrew S.} and Taylor, {Michael D.} and Chris Jones and Nada Jabado and Karajannis, {Matthias A.} and Roland Eils and Matthias Schlesner and Peter Lichter and {von Deimling}, Andreas and Pfister, {Stefan M.} and Ellison, {David W.} and Andrey Korshunov and Marcel Kool",

year = "2016",

month = feb,

day = "25",

doi = "10.1016/j.cell.2016.01.015",

language = "English",

volume = "164",

pages = "1060--1072",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "5",

}

Sturm, D, Orr, BA, Toprak, UH, Hovestadt, V, Jones, DTW, Capper, D, Sill, M, Buchhalter, I, Northcott, PA, Leis, I, Ryzhova, M, Koelsche, C, Pfaff, E, Allen, SJ, Balasubramanian, G, Worst, BC, Pajtler, KW, Brabetz, S, Johann, PD, Sahm, F, Reimand, J, Mackay, A, Carvalho, DM, Remke, M, Phillips, JJ, Perry, A, Cowdrey, C, Drissi, R, Fouladi, M, Giangaspero, F, Lastowska, M, Grajkowska, W, Scheurlen, W, Pietsch, T, Hagel, C, Gojo, J, Loetsch, D, Berger, W, Slavc, I, Haberler, C, Jouvet, A, Holm, S, Hofer, S, Prinz, M, Keohane, C, Fried, I, Mawrin, C, Scheie, D, Mobley, BC, Schniederjan, MJ, Santi, M, Buccoliero, AM, Dahiya, S, Kramm, CM, von Bueren, AO, von Hoff, K, Rutkowski, S, Herold-Mende, C, Fruehwald, MC, Milde, T, Hasselblatt, M, Wesseling, P, Roessler, J, Schueller, U, Ebinger, M, Schittenhelm, J, Frank, S, Grobholz, R, Vajtai, I, Hans, V, Schneppenheim, R, Zitterbart, K, Collins, VP, Aronica, E, Varlet, P, Puget, S, Dufour, C, Grill, J, Figarella-Branger, D, Wolter, M, Schuhmann, MU, Shalaby, T, Grotzer, M, van Meter, T, Monoranu, C-M, Felsberg, J, Reifenberger, G, Snuderl, M, Forrester, LA, Koster, J, Versteeg, R, Volckmann, R, van Sluis, P, Wolf, S, Mikkelsen, T, Gajjar, A, Aldape, K, Moore, AS, Taylor, MD, Jones, C, Jabado, N, Karajannis, MA, Eils, R, Schlesner, M, Lichter, P, von Deimling, A, Pfister, SM, Ellison, DW, Korshunov, A & Kool, M 2016, 'New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs', Cell, vol. 164, no. 5, pp. 1060-1072. https://doi.org/10.1016/j.cell.2016.01.015

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. / Sturm, Dominik; Orr, Brent A.; Toprak, Umut H.; Hovestadt, Volker; Jones, David T. W.; Capper, David; Sill, Martin; Buchhalter, Ivo; Northcott, Paul A.; Leis, Irina; Ryzhova, Marina; Koelsche, Christian; Pfaff, Elke; Allen, Sariah J.; Balasubramanian, Gnanaprakash; Worst, Barbara C.; Pajtler, Kristian W.; Brabetz, Sebastian; Johann, Pascal D.; Sahm, Felix; Reimand, Jueri; Mackay, Alan; Carvalho, Diana M.; Remke, Marc; Phillips, Joanna J.; Perry, Arie; Cowdrey, Cynthia; Drissi, Rachid; Fouladi, Maryam; Giangaspero, Felice; Lastowska, Maria; Grajkowska, Wieslawa; Scheurlen, Wolfram; Pietsch, Torsten; Hagel, Christian; Gojo, Johannes; Loetsch, Daniela; Berger, Walter; Slavc, Irene; Haberler, Christine; Jouvet, Anne; Holm, Stefan; Hofer, Silvia; Prinz, Marco; Keohane, Catherine; Fried, Iris; Mawrin, Christian; Scheie, David; Mobley, Bret C.; Schniederjan, Matthew J.; Santi, Mariarita; Buccoliero, Anna M.; Dahiya, Sonika; Kramm, Christof M.; von Bueren, Andre O.; von Hoff, Katja; Rutkowski, Stefan; Herold-Mende, Christel; Fruehwald, Michael C.; Milde, Till; Hasselblatt, Martin; Wesseling, Pieter; Roessler, Jochen; Schueller, Ulrich; Ebinger, Martin; Schittenhelm, Jens; Frank, Stephan; Grobholz, Rainer; Vajtai, Istvan; Hans, Volkmar; Schneppenheim, Reinhard; Zitterbart, Karel; Collins, V. Peter; Aronica, Eleonora; Varlet, Pascale; Puget, Stephanie; Dufour, Christelle; Grill, Jacques; Figarella-Branger, Dominique; Wolter, Marietta; Schuhmann, Martin U.; Shalaby, Tarek; Grotzer, Michael; van Meter, Timothy; Monoranu, Camelia-Maria; Felsberg, Joerg; Reifenberger, Guido; Snuderl, Matija; Forrester, Lynn Ann; Koster, Jan; Versteeg, Rogier; Volckmann, Richard; van Sluis, Peter; Wolf, Stephan; Mikkelsen, Tom; Gajjar, Amar; Aldape, Kenneth; Moore, Andrew S.; Taylor, Michael D.; Jones, Chris; Jabado, Nada; Karajannis, Matthias A.; Eils, Roland; Schlesner, Matthias; Lichter, Peter; von Deimling, Andreas; Pfister, Stefan M.; Ellison, David W.; Korshunov, Andrey; Kool, Marcel.

In: Cell, Vol. 164, No. 5, 25.02.2016, p. 1060-1072.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

AU - Sturm, Dominik

AU - Orr, Brent A.

AU - Toprak, Umut H.

AU - Hovestadt, Volker

AU - Jones, David T. W.

AU - Capper, David

AU - Sill, Martin

AU - Buchhalter, Ivo

AU - Northcott, Paul A.

AU - Leis, Irina

AU - Ryzhova, Marina

AU - Koelsche, Christian

AU - Pfaff, Elke

AU - Allen, Sariah J.

AU - Balasubramanian, Gnanaprakash

AU - Worst, Barbara C.

AU - Pajtler, Kristian W.

AU - Brabetz, Sebastian

AU - Johann, Pascal D.

AU - Sahm, Felix

AU - Reimand, Jueri

AU - Mackay, Alan

AU - Carvalho, Diana M.

AU - Remke, Marc

AU - Phillips, Joanna J.

AU - Perry, Arie

AU - Cowdrey, Cynthia

AU - Drissi, Rachid

AU - Fouladi, Maryam

AU - Giangaspero, Felice

AU - Lastowska, Maria

AU - Grajkowska, Wieslawa

AU - Scheurlen, Wolfram

AU - Pietsch, Torsten

AU - Hagel, Christian

AU - Gojo, Johannes

AU - Loetsch, Daniela

AU - Berger, Walter

AU - Slavc, Irene

AU - Haberler, Christine

AU - Jouvet, Anne

AU - Holm, Stefan

AU - Hofer, Silvia

AU - Prinz, Marco

AU - Keohane, Catherine

AU - Fried, Iris

AU - Mawrin, Christian

AU - Scheie, David

AU - Mobley, Bret C.

AU - Schniederjan, Matthew J.

AU - Santi, Mariarita

AU - Buccoliero, Anna M.

AU - Dahiya, Sonika

AU - Kramm, Christof M.

AU - von Bueren, Andre O.

AU - von Hoff, Katja

AU - Rutkowski, Stefan

AU - Herold-Mende, Christel

AU - Fruehwald, Michael C.

AU - Milde, Till

AU - Hasselblatt, Martin

AU - Wesseling, Pieter

AU - Roessler, Jochen

AU - Schueller, Ulrich

AU - Ebinger, Martin

AU - Schittenhelm, Jens

AU - Frank, Stephan

AU - Grobholz, Rainer

AU - Vajtai, Istvan

AU - Hans, Volkmar

AU - Schneppenheim, Reinhard

AU - Zitterbart, Karel

AU - Collins, V. Peter

AU - Aronica, Eleonora

AU - Varlet, Pascale

AU - Puget, Stephanie

AU - Dufour, Christelle

AU - Grill, Jacques

AU - Figarella-Branger, Dominique

AU - Wolter, Marietta

AU - Schuhmann, Martin U.

AU - Shalaby, Tarek

AU - Grotzer, Michael

AU - van Meter, Timothy

AU - Monoranu, Camelia-Maria

AU - Felsberg, Joerg

AU - Reifenberger, Guido

AU - Snuderl, Matija

AU - Forrester, Lynn Ann

AU - Koster, Jan

AU - Versteeg, Rogier

AU - Volckmann, Richard

AU - van Sluis, Peter

AU - Wolf, Stephan

AU - Mikkelsen, Tom

AU - Gajjar, Amar

AU - Aldape, Kenneth

AU - Moore, Andrew S.

AU - Taylor, Michael D.

AU - Jones, Chris

AU - Jabado, Nada

AU - Karajannis, Matthias A.

AU - Eils, Roland

AU - Schlesner, Matthias

AU - Lichter, Peter

AU - von Deimling, Andreas

AU - Pfister, Stefan M.

AU - Ellison, David W.

AU - Korshunov, Andrey

AU - Kool, Marcel

PY - 2016/2/25

Y1 - 2016/2/25

U2 - 10.1016/j.cell.2016.01.015

DO - 10.1016/j.cell.2016.01.015

M3 - Article

C2 - 26919435

VL - 164

SP - 1060

EP - 1072

JO - Cell

JF - Cell

SN - 0092-8674

IS - 5

ER -