Nieuwe therapeutische benadering van amyloïdose: Vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

A. W. Lemstra; P. Eikelenboom; E. W. Meijer; W. A. Van Gool

Nieuwe therapeutische benadering van amyloïdose: Vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

Translated title of the contribution: Novel therapeutic approach to amyloidosis: No implications as yet for patients with Alzheimer's disease

A. W. Lemstra^*, P. Eikelenboom, E. W. Meijer, W. A. Van Gool

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilising these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.

Translated title of the contribution	Novel therapeutic approach to amyloidosis: No implications as yet for patients with Alzheimer's disease
Original language	Dutch
Pages (from-to)	1720-1723
Number of pages	4
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	146
Issue number	37
Publication status	Published - 14 Sep 2002
Externally published	Yes

Cite this

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abstract = "Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilising these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.",

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T2 - Vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

AU - Lemstra, A. W.

AU - Eikelenboom, P.

AU - Meijer, E. W.

AU - Van Gool, W. A.

PY - 2002/9/14

Y1 - 2002/9/14

N2 - Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilising these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.

AB - Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilising these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.

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M3 - Review article

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JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

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IS - 37

ER -

Nieuwe therapeutische benadering van amyloïdose: Vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

Abstract

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