Novel applications of therapeutic hypothermia: report of three cases.

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Therapeutic hypothermia can provide neuroprotection in various situations where global or focal neurological injury has occurred. Hypothermia has been shown to be effective in a large number of animal experiments. In clinical trials, hypothermia has been used in patients with postanoxic injury following cardiopulmonary resuscitation, in traumatic brain injury with high intracranial pressure, in the perioperative setting during various surgical procedures and for various other indications. There is thus evidence that hypothermia can be effective in various situations of neurological injury, although a number of questions remain unanswered. We describe three patients with unusual causes of neurological injury, whose clinical situation was in fundamental aspects analogous to conditions where hypothermia has been shown to be effective.

Original languageEnglish
JournalCritical care (London, England)
Volume8
Issue number5
Publication statusPublished - 1 Jan 2004

Cite this

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title = "Novel applications of therapeutic hypothermia: report of three cases.",
abstract = "Therapeutic hypothermia can provide neuroprotection in various situations where global or focal neurological injury has occurred. Hypothermia has been shown to be effective in a large number of animal experiments. In clinical trials, hypothermia has been used in patients with postanoxic injury following cardiopulmonary resuscitation, in traumatic brain injury with high intracranial pressure, in the perioperative setting during various surgical procedures and for various other indications. There is thus evidence that hypothermia can be effective in various situations of neurological injury, although a number of questions remain unanswered. We describe three patients with unusual causes of neurological injury, whose clinical situation was in fundamental aspects analogous to conditions where hypothermia has been shown to be effective.",
author = "Hartemink, {Koen J.} and Willem Wisselink and Rauwerda, {Jan A.} and Girbes, {Armand R.J.} and Polderman, {Kees H.}",
year = "2004",
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language = "English",
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Novel applications of therapeutic hypothermia : report of three cases. / Hartemink, Koen J.; Wisselink, Willem; Rauwerda, Jan A.; Girbes, Armand R.J.; Polderman, Kees H.

In: Critical care (London, England), Vol. 8, No. 5, 01.01.2004.

Research output: Contribution to journalArticleAcademicpeer-review

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AB - Therapeutic hypothermia can provide neuroprotection in various situations where global or focal neurological injury has occurred. Hypothermia has been shown to be effective in a large number of animal experiments. In clinical trials, hypothermia has been used in patients with postanoxic injury following cardiopulmonary resuscitation, in traumatic brain injury with high intracranial pressure, in the perioperative setting during various surgical procedures and for various other indications. There is thus evidence that hypothermia can be effective in various situations of neurological injury, although a number of questions remain unanswered. We describe three patients with unusual causes of neurological injury, whose clinical situation was in fundamental aspects analogous to conditions where hypothermia has been shown to be effective.

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