Novel approaches using mesenchymal stem cells for curing peripheral nerve injuries

Forouzan Yousefi, Fahimeh Lavi Arab, Karim Nikkhah, Houshang Amiri, Mahmoud Mahmoudi

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Peripheral nerve injury (PNI) is a common life-changing disability of peripheral nervous system with significant socioeconomic consequences. Conventional therapeutic approaches for PNI have several drawbacks such as need to autologous nerve scarifying, surplus surgery, and difficult accessibility to donor nerve; therefore, other therapeutic strategies such as mesenchymal stem cells (MSCs) therapy are getting more interesting. MSCs have been proved to be safe and efficient in numerous degenerative diseases of central and peripheral nervous systems. In this paper, we review novel biotechnological advancements in treating PNI using MSCs.
Original languageEnglish
Pages (from-to)99-108
JournalLife Sciences
Volume221
DOIs
Publication statusPublished - 2019

Cite this

Yousefi, F., Lavi Arab, F., Nikkhah, K., Amiri, H., & Mahmoudi, M. (2019). Novel approaches using mesenchymal stem cells for curing peripheral nerve injuries. Life Sciences, 221, 99-108. https://doi.org/10.1016/j.lfs.2019.01.052